MeCP2 in the regulation of neural activity: Rett syndrome pathophysiological perspectives [0.03%]
MeCP2在神经活动调节中的作用：雷特综合征病理生理学观点
Vishnu Anand Cuddapah,Elvee Nwaobi Sinifunanya,Alan K Percy et al.
Vishnu Anand Cuddapah et al.
Rett syndrome (RTT), an X-linked neurodevelopment disorder, occurs in approximately one out of 10,000 females. Individuals afflicted by RTT display a constellation of signs and symptoms, affecting nearly every organ system. Most striking ar...
The role of cell transplantation in modifying the course of limb girdle muscular dystrophy: a longitudinal 5-year study [0.03%]
细胞移植在改变肢带型肌营养不良病程中的作用：一项为期五年的纵向研究
Alok Sharma,Hemangi Sane,Nandini Gokulchandran et al.
Alok Sharma et al.
Limb girdle muscular dystrophy (LGMD), a group of progressive degenerative disorders, causes functional limitation affecting the quality of life. Cell therapy is being widely explored and preliminary studies have shown beneficial effects. C...
Erratum: Multimodal intervention improves fatigue and quality of life in subjects with progressive multiple sclerosis: a pilot study [Corrigendum] [0.03%]
多模态干预改善进行性多发性硬化患者的疲劳和生活质量：一项试点研究的勘误表
[This corrects the article DOI: 10.2147/DNND.S76523.]. © 2015 Bisht et al.
Clinical and experimental studies of multiple sclerosis in Russia: experience of the leading national research centers [0.03%]
俄罗斯多发性硬化临床和实验研究：国家主要研究中心的经验总结
Igor A Zavalishin,Alexey A Belogurov Jr,Yakov A Lomakin et al.
Igor A Zavalishin et al.
Mechanisms of axonal damage and adaptive capacity in multiple sclerosis (MS), including cortical reorganization, have been actively studied in recent years. The lack of regenerative capabilities and the irreversibility of neurodegeneration ...
Faraz Farooq,Alex E MacKenzie
Faraz Farooq
Spinal muscular atrophy is one of the most common inherited neuromuscular conditions; our understanding of the genetic pathology and translational research coming from this insight has made significant progress over the past decade. This sh...
Critical appraisal of rotigotine transdermal system in management of Parkinson's disease and restless legs syndrome - patient considerations [0.03%]
罗替戈汀透皮贴剂在帕金森病和不安腿综合征管理中的患者考虑因素批判性评价
Tigran Kesayan,Jessica D Shaw,Tracy M Jones et al.
Tigran Kesayan et al.
Rotigotine (RTG) is a dopamine agonist that is used as mono and adjunct therapy to treat Parkinson's disease, and as therapy for moderate-to-severe restless legs syndrome. RTG is the only dopamine agonist currently available as a 24-hour/da...
Advances in the management of relapsing-remitting multiple sclerosis: role of oral dimethyl fumarate (BG-12) [0.03%]
复发缓解型多发性硬化的治疗进展：口服二甲基富马酸（BG-12）的作用
A Scott Nielsen
A Scott Nielsen
Multiple sclerosis is a complex and chronic inflammatory disease of the central nervous system which affects an estimated 2.3 million individuals worldwide. Genetic research has uncovered over 100 immune-related genes associated with the di...
Clinical diagnosis and management in early Huntington's disease: a review [0.03%]
早期亨廷顿舞蹈病的临床诊断与治疗综述
Johannes Schiefer,Cornelius J Werner,Kathrin Reetz
Johannes Schiefer
This review focuses on clinical diagnosis and both pharmacological and nonpharmacological therapeutic options in early stages of the autosomal dominant inherited neurodegenerative Huntington's disease (HD). The available literature has been...
Apolipoprotein E ε-4 as a genetic determinant of Alzheimer's disease heterogeneity [0.03%]
APOEε-4是阿尔茨海默病异质性的遗传决定因素之一
M J Kotze,H K Lückhoff,T Brand et al.
M J Kotze et al.
Alzheimer's disease (AD) displays a high degree of heterogeneity in terms of its etiology, presentation, prognosis, and treatment response. This can partly be explained by high-penetrance mutations in the amyloid precursor protein, presenil...
Pratiksha G Gandhi,Hr Rao Gundu
Pratiksha G Gandhi
Background: The sudomotor test is used to evaluate the postganglionic cholinergic sympathetic nervous system. The aim of this study was to evaluate the efficacy of a sudomotor testing device to detect peripheral distal ne...