Paul J Kueck,Jill K Morris,John A Stanford
Paul J Kueck
Obesity is increasing in prevalence across all age groups. Long-term obesity can lead to the development of metabolic and cardiovascular diseases through its effects on adipose, skeletal muscle, and liver tissue. Pathological mechanisms ass...
Development and Validation of a Risk Prediction Model to Estimate the Risk of Stroke Among Hypertensive Patients in University of Gondar Comprehensive Specialized Hospital, Gondar, 2012 to 2022 [0.03%]
2012至2022年贡达尔大学综合专科医院高血压患者卒中风险预测模型的研制与验证
Yazachew Moges Chekol,Mehari Woldemariam Merid,Getayeneh Antehunegn Tesema et al.
Yazachew Moges Chekol et al.
Background: A risk prediction model to predict the risk of stroke has been developed for hypertensive patients. However, the discriminating power is poor, and the predictors are not easily accessible in low-income countri...
Practical Guidance on the Use of Cladribine Tablets in the Management or Relapsing Multiple Sclerosis: Expert Opinion from Qatar [0.03%]
克拉利odbbl片剂治疗复发性多发性硬化症的实践指导——卡塔尔专家意见
Dirk Deleu,Beatriz Garcia Canibano,Osama Elalamy et al.
Dirk Deleu et al.
The increasing availability of high-efficacy disease-modifying therapies (DMT) for the management of relapsing multiple sclerosis (RMS) has increased the potential for individualised patient management but has added complexity to the design...
Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer's Disease Mouse Model: Role of Microglial and Neuroinflammation [0.03%]
瘦素对APP/PS1阿尔茨海默病小鼠模型的神经保护作用：微胶质细胞和神经炎症的作用机制研究
Jing Ma,Yi-Hui Hou,Zhe-Yan Liao et al.
Jing Ma et al.
Background: Microglia are closely linked to Alzheimer's disease (AD) many years ago; however, the pathological mechanisms of AD remain unclear. The purpose of this study was to determine whether leptin affected microglia ...
Interventions to Improve Quality of Life in Multiple Sclerosis: New Opportunities and Key Talking Points [0.03%]
改善多发性硬化症患者生活质量的干预措施：新机遇和关键讨论点
Erin Faraclas
Erin Faraclas
Background: Today, living well with multiple sclerosis (MS) is often measured by a person's overall quality of life rather than being limited to the more traditional metrics of reduced frequency of relapses or progression...
Risk of Obstructive Sleep Apnea in Saudi Male Boys with Duchenne Muscular Dystrophy (DMD) [0.03%]
沙特阿拉伯杜氏肌营养不良症男童阻塞性睡眠呼吸暂停的风险
Ahmed Bamaga,Lama Alqarni
Ahmed Bamaga
Background: Duchenne muscular dystrophy (DMD) patients are at a high risk of developing sleep-related breathing disorders (SRBD) such as obstructive sleep apnea (OSA). This study aimed to determine the risk of developing ...
Sexual Motivation in Persons with Multiple Sclerosis: A Controlled Cross-Sectional Study [0.03%]
多发性硬化症患者的性动机：一项对照横断面研究
Petra Prinssen,Peter Joseph Jongen,Marco Heerings et al.
Petra Prinssen et al.
Purpose: Sexual motives are major determinants of sexual behaviour. It has been known that sexual motives may vary according to circumstances. Multiple sclerosis (MS) is a chronic disease causing a broad range of symptoms...
Neuroimaging Correlates of Patient-Reported Outcomes in Multiple Sclerosis [0.03%]
多发性硬化症患者报告结果的神经影像学相关因素
Dejan Jakimovski,Taylor R Wicks,Niels Bergsland et al.
Dejan Jakimovski et al.
Background: Patient-reported outcomes (PROs) are increasingly associated with concurrent and future impairments in persons with multiple sclerosis (pwMS). The structural and pathological relationships with PROs in pwMS ha...
Ultrasound-Guided Percutaneous Neuromodulation in Multiple Sclerosis: A Case Report [0.03%]
多发性硬化症的超声引导经皮神经调节治疗：一例报告
Alberto Javier-Ormazábal,Pablo Herrero,Montserrat González-Platas
Alberto Javier-Ormazábal
Multiple sclerosis is a degenerative inflammatory disease that causes different musculoskeletal problems. Its impact has led to the study of treatment alternatives such as the use of invasive physiotherapy. In this study, we analyze the eff...
Mitochondrial Toxicant-Induced Neuronal Apoptosis in Parkinson's Disease: What We Know so Far [0.03%]
帕金森病线粒体毒物诱导的神经元凋亡：迄今所知
Narmadhaa Sivagurunathan,Priyadharshini Gnanasekaran,Latchoumycandane Calivarathan
Narmadhaa Sivagurunathan
Parkinson's disease (PD) is one of the most common progressive neurodegenerative diseases caused by the loss of dopamine-producing neuronal cells in the region of substantia nigra pars compacta of the brain. During biological aging, neurona...