Tactical Considerations for Designing Real-World Studies: Fit-for-Purpose Designs That Bridge Research and Practice [0.03%]
现实世界研究的设计策略：连接研究与实践的务实设计考虑因素
Nancy A Dreyer,Christina D Mack
Nancy A Dreyer
Real-world evidence (RWE) is being used to provide information on diverse groups of patients who may be highly impacted by disease but are not typically studied in traditional randomized clinical trials (RCT) and to obtain insights from eve...
Real World Data Studies of Antineoplastic Drugs: How Can They Be Improved to Steer Everyday Use in the Clinic? [0.03%]
真实世界数据对抗肿瘤药物的研究：如何改进以指导临床常规使用？
Gincy George,Beth Russell,Anne Rigg et al.
Gincy George et al.
There is a growing interest in real world evidence when developing antineoplastic drugs owing to the shorter length of time and low costs compared to randomised controlled trials. External validity of studies in the regulatory phase can be ...
Real-World Impact of Robotic-Assisted Bronchoscopy on the Staging and Diagnosis of Lung Cancer: The Shape of Current and Potential Opportunities [0.03%]
机器人辅助支气管镜在肺癌分期和诊断中的真实世界影响：当前和潜在机遇的展望
Gabriel Ortiz-Jaimes,Janani Reisenauer
Gabriel Ortiz-Jaimes
The approach to peripheral pulmonary lesions (PPL) has been evolving continuously. Advanced bronchoscopic navigational techniques have improved the airway-based approaches to these lesions. Robotic Assisted Bronchoscopy (RAB) can be conside...
Amir Sara,Samantha M Ruff,Anne M Noonan et al.
Amir Sara et al.
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality worldwide and accounts for 90% of all primary liver cancers. Chronic inflammation is the hallmark across most prevalent etiologies among which HBV is ...
Clinical Management of COPD in the Real World: Can Studies Reveal Errors in Management and Pathways to Improve Patient Care? [0.03%]
真实世界中的慢性阻塞性肺疾病的临床治疗：研究能否揭示诊治错误并改进患者治疗？
David M G Halpin
David M G Halpin
Real world data comprise information on health care that is derived from multiple sources outside typical clinical research settings. This review focuses on what real world evidence tells us about problems with the diagnosis of chronic obst...
Administrative Databases and Diagnostic Therapeutic and Assistance Paths -PDTA- in the Monitoring Treatment of Rheumatoid Arthritis: The Experience of ATS Pavia [0.03%]
行政数据库和诊断治疗辅助路径(PDTA)在类风湿关节炎监测治疗中的应用——帕维亚ATS的实践经验
Giacomo M Bruno,Maria Chiara Valentino,Alessandra Brunetti et al.
Giacomo M Bruno et al.
Background: The current flows of the SSN represent the set of interest whose interconnection alone justifies the current study. These flows can be interconnected with other sources, institutional or otherwise, in order to...
Data-Resource Profile: United Kingdom Optimum Patient Care Research Database [0.03%]
数据资源概况：英国最佳临床实践研究数据库
Anita Lynam,Charlotte Curtis,Brooklyn Stanley et al.
Anita Lynam et al.
Introduction: Electronic medical records (EMRs) maintained in primary care in the UK and collected and stored in EMR databases offer a world-leading resource for observational clinical research. We aimed to profile one su...
Alignment of Physician-Stated vs Clinically Derived Reference Fibrosis Score in Patients with Non-Alcoholic Steatohepatitis: A Real-World European Survey [0.03%]
欧洲真实世界非酒精性脂肪肝病患者的医师报告参考纤维化评分与临床导出的参考纤维化评分的一致性调查
Quentin M Anstee,Kate Hallsworth,Niall Lynch et al.
Quentin M Anstee et al.
Objective: Stratifying disease severity in patients with non-alcoholic steatohepatitis (NASH) is essential for appropriate treatment and long-term management. Liver biopsy is the reference standard for fibrosis severity i...
Real-Life Effectiveness of MP-AzeFlu (Dymista®) in Swedish Patients with Persistent Allergic Rhinitis, Assessed by the Visual Analogue Scale [0.03%]
视敏度量表评估的MP-AzeFlu(Dymista®)在瑞典持续性过敏性鼻炎患者中的实际疗效
Pär Stjärne,Duc Tung Nguyen,Hans Christian Kuhl
Pär Stjärne
Background: Many allergic rhinitis (AR) patients have moderate/severe persistent disease. MP-AzeFlu (Dymista®) comprises intranasal azelastine hydrochloride and fluticasone propionate in a novel formulation delivered in ...
Impact of the COVID-19 Pandemic on Trauma Service Utilization at a New York City Level I Trauma Center [0.03%]
新冠肺炎大流行对纽约市一家一级创伤中心创伤服务利用的影响
Benjamin Rosen,Annemarie L Pelle,Nisha A Lakhi
Benjamin Rosen
Background: The COVID-19 pandemic globally impacted trauma facilities and overall healthcare utilization. This study was conducted to characterize the utilization of trauma services at our Level I Trauma Center in New Yor...