Using Claims Data to Predict Pre-Operative BMI Among Bariatric Surgery Patients: Development of the BMI Before Bariatric Surgery Scoring System (B3S3) [0.03%]
利用索赔数据预测代谢手术患者的术前BMI值：建立术前BMI评分系统(B3S3)
Jenna Wong,Xiaojuan Li,David E Arterburn et al.
Jenna Wong et al.
Background: Lack of body mass index (BMI) measurements limits the utility of claims data for bariatric surgery research, but pre-operative BMI may be imputed due to existence of weight-related diagnosis codes and BMI-rela...
Trends in Systemic Glucocorticoid Utilization in the United Kingdom from 1990 to 2019: A Population-Based, Serial Cross-Sectional Analysis [0.03%]
1990至2019年英国系统性糖皮质激素使用的流行情况：基于人群的系列横断面分析
Andrew N Menzies-Gow,Trung N Tran,Brooklyn Stanley et al.
Andrew N Menzies-Gow et al.
Purpose: Associations between systemic glucocorticoid (SGC) exposure and risk for adverse outcomes have spurred a move toward steroid-sparing treatment strategies. Real-world changes in SGC exposure over time, after the i...
Difficult-To-Treat and Severe Asthma: Can Real-World Studies On Effectiveness of Biological Treatments Change the Lives of Patients? [0.03%]
难以治疗和严重哮喘：针对生物制剂疗效的真实世界研究能改变患者的生活吗？
Corrado Pelaia,Antonio Giacalone,Gianluca Ippolito et al.
Corrado Pelaia et al.
Many different phenotypes that characterize severe asthma are supported by intricate pathomechanisms called endotypes. The latter are driven by molecular interactions, mediated by intercellular networks. With regard to the biological treatm...
Marielen Reinhardt,Tobias Schupp,Mohammad Abumayyaleh et al.
Marielen Reinhardt et al.
Objective: The study investigates the prognostic impact of body mass index (BMI) in patients hospitalized with heart failure with mildly reduced ejection fraction (HFmrEF). ...
Saeed Shakibfar,Kristine H Allin,Tine Jess et al.
Saeed Shakibfar et al.
Aim: Drug repurposing, utilizing electronic healthcare records (EHRs), offers a promising alternative by repurposing existing drugs for new therapeutic indications, especially for patients lacking effective therapies. Int...
Risk of Pneumonia in Patients with COPD Initiating Fixed Dose Inhaled Corticosteroid (ICS) / Long-Acting Bronchodilator (LABD) Formulations Containing Extrafine Beclometasone Dipropionate versus Patients Initiating LABD Without ICS [0.03%]
使用吸入性皮质类固醇(ICS)/长效支气管扩张剂(LABD)固定剂量组合物（含有超微比氯米松二丙酸酯）的慢性阻塞性肺疾病患者发生肺炎的风险与仅使用LABD的患者相比的风险研究
David Price,William Henley,José Eduardo Delfini Cançado et al.
David Price et al.
Background: Combined ICS and long-acting bronchodilators (LABD) more effectively reduce COPD exacerbations than LABD therapy alone. Corticosteroid-related adverse effects, including pneumonia, limit ICS use. Previous data...
Prediction Model with Validation for Polioseronegativity in Malnourished Children from Poliomyelitis Transmission High-Risk Area of the Democratic Republic of the Congo (DRC) [0.03%]
刚果民主共和国(DRC)脊灰高传播风险区营养不良儿童脊灰抗体阴性的预测模型及验证研究
Guillaume Ngoie Mwamba,Michel Kabamba,Nicole A Hoff et al.
Guillaume Ngoie Mwamba et al.
Background: Malnutrition is identified as a risk factor for insufficient polio seroconversion in the context of a vaccine-derived poliovirus (VDPV) outbreak-prone region. In the Democratic Republic of Congo (DRC), underwe...
Avelumab for Advanced Merkel Cell Carcinoma: Global Real-World Data on Patient Response and Survival [0.03%]
阿维鲁单抗治疗晚期默克尔细胞癌：患者反应和生存的全球真实世界数据
Rishabh Lohray,Kritin K Verma,Leo L Wang et al.
Rishabh Lohray et al.
Introduction: Avelumab is a programmed cell death-ligand 1 (PD-L1) inhibitor approved by the Food and Drug Administration for advanced Merkel cell carcinoma (MCC). Studies conducted in real-world settings have shed light ...
Breda Cushen,Mariko Siyue Koh,Trung N Tran et al.
Breda Cushen et al.
Aim: The International Severe Asthma Registry (ISAR; http://isaregistries.org/) uses standardised variables to enable multi-country and adequately powered research in severe asthma. This study aims to look at the data cou...
Development of an Asthma Exacerbation Risk Prediction Model for Conversational Use by Adults in England [0.03%]
在英格兰开发一种成人哮喘恶化风险预测模型用于对话使用
Constantinos Kallis,Rafael A Calvo,Bjorn Schuller et al.
Constantinos Kallis et al.
Background: Improving accurate risk assessment of asthma exacerbations, and reduction via relevant behaviour change among people with asthma could save lives and reduce health care costs. We developed a simple personalise...