Evaluating the Potential of Prevalent New User Design as an Alternative When New User Design is Impractical [0.03%]
当新的用户设计不可行时评估现有新用户设计的潜在替代作用
Takuma Koinuma,Manabu Akazawa
Takuma Koinuma
Purpose: The New User Design can be applied if the target drug has not been administered for a specified period. Therefore, comparisons between drugs administered alone are easier to undertake than comparisons of drugs us...
Association of Frequent Short-Acting Beta-Agonist Inhaler Prescriptions with Acute Cardiovascular Events [0.03%]
短效β受体激动剂吸入剂频繁处方与急性心血管事件的关系
Paul E Pfeffer,Heath Heatley,Richard Hubbard et al.
Paul E Pfeffer et al.
Background: Frequent usage of short-acting beta-agonist (SABA) reliever inhalers is strongly associated with exacerbations of asthma and chronic obstructive pulmonary disease (COPD), in turn associated with cardiovascular...
Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY [0.03%]
NOVELTY中哮喘和/或慢阻肺患者使用SGRQ评估EQ-5D-5L的映射关系
Dan Jackson,Anna Quinton,Fanni Zhang et al.
Dan Jackson et al.
Purpose: The St George's Respiratory Questionnaire (SGRQ) measures health status in obstructive airways disease. Starkie et al proposed an algorithm for mapping the SGRQ to EQ-5D-5L, a preference-based utility measure, in...
Nina L Wittwer,Christoph R Meier,Martin J Recknagel et al.
Nina L Wittwer et al.
Medifilm is a company that blisters drug therapies recorded by pharmacists in the Medifilm software. The Medifilm dataset collates this information and provides details on drug substances, dosages, pharmacotherapy duration, the sequence of ...
Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS) [0.03%]
糖皮质激素盐皮质激素受体拮抗剂的不良反应及停药原因患者调查（RELICS-PS）
Emma L Richard,Judith J Stephenson,Nihar R Desai et al.
Emma L Richard et al.
Purpose: To understand steroidal mineralocorticoid receptor antagonists (sMRAs) treatment patterns and side effects from patients' perspectives. Methods: ...
Shifting from Traditional to Pragmatic Randomized Controlled Trials: Insights and Lessons Learned from the Toddler Oral Health Intervention [0.03%]
从传统的RCT向实用的RCT转变——幼儿口腔健康干预研究的启示及经验教训
Brenda G Grift,Peggy C J M van Spreuwel,Josef J J M Bruers et al.
Brenda G Grift et al.
Purpose: This article examines the implementation of the Toddler Oral Health Intervention (TOHI) protocol, emphasizing feasibility, recruitment, retention, and protocol adherence rather than clinical outcomes. It discusse...
Predicting Risk of Morbidities Associated with Oral Corticosteroid Prescription for Asthma [0.03%]
预测与哮喘口服皮质类固醇处方相关的疾病风险
Brooklyn Stanley,Jatin Chapaneri,Mina Khezrian et al.
Brooklyn Stanley et al.
Background: Oral corticosteroids (OCS) are commonly used to treat asthma but increase the risks for multiple morbidities; reducing OCS exposure may benefit patients. We analysed independent risk factors and longitudinal c...
Real-World Biologic Use Patterns in Severe Asthma, 2015-2021: The CLEAR Study [0.03%]
真实世界中严重哮喘患者生物制剂使用模式，2015-2021年：CLEAR研究
Trung N Tran,Stephanie Chen,Benjamin Emmanuel et al.
Trung N Tran et al.
Background: Biologics targeting immunoglobulin E, interleukin (IL)-4/IL-13 or IL-5 signaling are effective at treating severe asthma; however, individual patients' responses may be suboptimal, leading to therapy switching...
Better Understanding Rehabilitation of Motor Symptoms: Insights from the Use of Wearables [0.03%]
更好地理解运动症状的康复：来自可穿戴设备使用的见解
Yunus Celik,Conor Wall,Jason Moore et al.
Yunus Celik et al.
Movement disorders present a substantial challenge by adversely affecting daily routines and overall well-being through a diverse spectrum of motor symptoms. Traditionally, motor symptoms have been evaluated through manual observational met...
A Prospective Observational Study to Evaluate the Actual Use of 1% Pimecrolimus in Chinese Patients with Mild-to-Moderate Atopic Dermatitis Affecting Sensitive Skin Areas [0.03%]
一项前瞻性观察研究评估1%吡美莫司在中国轻中度特应性皮炎敏感皮肤区域患者中的实际使用情况
Zhiqiang Xie,Jianmin Chang,Lin Ma et al.
Zhiqiang Xie et al.
Introduction: Atopic dermatitis (AD) is a common inflammatory skin disorder that affects both children and adults, characterized by pruritus and scaly, dry eczematous lesions. This study aimed to gather knowledge on the a...