Clinical Outcomes of Ablation for Persistent Atrial Fibrillation with Zero or Minimal Fluoroscopy [0.03%]
零或最小剂量放射引导下持续性房颤射频消融的临床疗效研究
Jose Osorio,Gustavo Morales,Anil Rajendra et al.
Jose Osorio et al.
Purpose: Recent developments in electroanatomical mapping (EAM), intracardiac echocardiography, and sheath technology have allowed for a pronounced reduction or complete elimination of fluoroscopy during catheter ablation...
Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM [0.03%]
专家视角：下一代卫生指导原则的意见征集——如何在以证据为基础的医疗中融合真实世界证据
Stefano Del Giacco,Giorgio Walter Canonica,Ioana Agache et al.
Stefano Del Giacco et al.
Integrating real-world evidence (RWE) into evidence-based medicine (EBM) enhances healthcare decision-making. RWE provides insights into the real-world effectiveness and safety of therapies and health technologies, filling gaps that clinica...
Evaluating the Potential of Prevalent New User Design as an Alternative When New User Design is Impractical [0.03%]
当新的用户设计不可行时评估现有新用户设计的潜在替代作用
Takuma Koinuma,Manabu Akazawa
Takuma Koinuma
Purpose: The New User Design can be applied if the target drug has not been administered for a specified period. Therefore, comparisons between drugs administered alone are easier to undertake than comparisons of drugs us...
Association of Frequent Short-Acting Beta-Agonist Inhaler Prescriptions with Acute Cardiovascular Events [0.03%]
短效β受体激动剂吸入剂频繁处方与急性心血管事件的关系
Paul E Pfeffer,Heath Heatley,Richard Hubbard et al.
Paul E Pfeffer et al.
Background: Frequent usage of short-acting beta-agonist (SABA) reliever inhalers is strongly associated with exacerbations of asthma and chronic obstructive pulmonary disease (COPD), in turn associated with cardiovascular...
Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY [0.03%]
NOVELTY中哮喘和/或慢阻肺患者使用SGRQ评估EQ-5D-5L的映射关系
Dan Jackson,Anna Quinton,Fanni Zhang et al.
Dan Jackson et al.
Purpose: The St George's Respiratory Questionnaire (SGRQ) measures health status in obstructive airways disease. Starkie et al proposed an algorithm for mapping the SGRQ to EQ-5D-5L, a preference-based utility measure, in...
Nina L Wittwer,Christoph R Meier,Martin J Recknagel et al.
Nina L Wittwer et al.
Medifilm is a company that blisters drug therapies recorded by pharmacists in the Medifilm software. The Medifilm dataset collates this information and provides details on drug substances, dosages, pharmacotherapy duration, the sequence of ...
Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS) [0.03%]
糖皮质激素盐皮质激素受体拮抗剂的不良反应及停药原因患者调查（RELICS-PS）
Emma L Richard,Judith J Stephenson,Nihar R Desai et al.
Emma L Richard et al.
Purpose: To understand steroidal mineralocorticoid receptor antagonists (sMRAs) treatment patterns and side effects from patients' perspectives. Methods: ...
Shifting from Traditional to Pragmatic Randomized Controlled Trials: Insights and Lessons Learned from the Toddler Oral Health Intervention [0.03%]
从传统的RCT向实用的RCT转变——幼儿口腔健康干预研究的启示及经验教训
Brenda G Grift,Peggy C J M van Spreuwel,Josef J J M Bruers et al.
Brenda G Grift et al.
Purpose: This article examines the implementation of the Toddler Oral Health Intervention (TOHI) protocol, emphasizing feasibility, recruitment, retention, and protocol adherence rather than clinical outcomes. It discusse...
Predicting Risk of Morbidities Associated with Oral Corticosteroid Prescription for Asthma [0.03%]
预测与哮喘口服皮质类固醇处方相关的疾病风险
Brooklyn Stanley,Jatin Chapaneri,Mina Khezrian et al.
Brooklyn Stanley et al.
Background: Oral corticosteroids (OCS) are commonly used to treat asthma but increase the risks for multiple morbidities; reducing OCS exposure may benefit patients. We analysed independent risk factors and longitudinal c...
Real-World Biologic Use Patterns in Severe Asthma, 2015-2021: The CLEAR Study [0.03%]
真实世界中严重哮喘患者生物制剂使用模式，2015-2021年：CLEAR研究
Trung N Tran,Stephanie Chen,Benjamin Emmanuel et al.
Trung N Tran et al.
Background: Biologics targeting immunoglobulin E, interleukin (IL)-4/IL-13 or IL-5 signaling are effective at treating severe asthma; however, individual patients' responses may be suboptimal, leading to therapy switching...