Autoinjectors for administration of interferon beta-1b in multiple sclerosis: patient preferences and the ExtaviPro™ 30G and Betacomfort® devices [0.03%]
干扰素β-1b自动注射器的患者偏好及ExtaviPro™ 30G和Betacomfort®注射笔评估
Kunal Thakur,Laure Manuel,Mark Tomlinson
Kunal Thakur
Background: The ExtaviPro™ 30G autoinjector has been developed for self-administration of interferon beta-1b (Extavia®), which is used as a first-line, parenteral, disease-modifying therapy in multiple sclerosis (MS). T...
Protocol for the asthma tools study: a pragmatic practice-based research network trial [0.03%]
哮喘工具研究的方案——基于实践的研究网络试验
Barbara P Yawn,Susan Bertram,Margary Kurland et al.
Barbara P Yawn et al.
Background: Asthma is common among children, adolescents, and adults. However, management of asthma often fails to follow evidence-based guidelines. Control assessments have been developed, validated against expert opinio...
Barbara P Yawn,Peter Wollan,Matthew Rank
Barbara P Yawn
Purpose: Chronic obstructive pulmonary disease (COPD) is usually recognized in its later stages, delaying therapeutic opportunities. Screening questionnaires have modest sensitivities and specificities. Adding questions a...
Partial response to proton pump inhibitor therapy for GERD: observational study of patient characteristics, burden of disease, and costs in the USA [0.03%]
GERD患者接受质子泵抑制剂治疗的不全缓解现象：一项美国患者的观察性研究及其疾病负担和成本分析
Nils-Olov Stålhammar,Brennan M Spiegel,Helena Granstedt Löfman et al.
Nils-Olov Stålhammar et al.
Background: Disease burden and associated costs are not well understood among patients with gastroesophageal reflux disease (GERD) who have persistent symptoms despite optimized proton pump inhibitor (PPI) therapy. The ai...
The challenge of recruiting in primary care for a trial of telemonitoring in asthma: an observational study [0.03%]
哮喘远程监控试验基层医疗招募观察性研究的挑战
Shweta Malhotra,Stanley D Musgrave,Hilary Pinnock et al.
Shweta Malhotra et al.
Aim: Achieving target recruitment in randomized controlled trials (RCTs) is challenging. This paper compares our experience of recruiting for an RCT with the predictions made in our proposal. ...
One-year outcomes in schizophrenia after switching from typical antipsychotics to olanzapine in Japan: an observational study [0.03%]
日本一期研究：由常规抗精神病药物换用奥氮平治疗精神分裂症一年的疗效观察性研究
Wenyu Ye,Shinji Fujikoshi,Naohiro Nakahara et al.
Wenyu Ye et al.
Background: The purpose of this study was to assess the 1-year clinical, functional, and safety-related outcomes following a switch to olanzapine of at least one typical antipsychotic drug in the previous regimen in the t...
Schizophrenia Outpatient Health Outcomes study: twelve-month findings [0.03%]
精神分裂症门诊预后研究（SOCRATES）的12个月随访结果分析
Diego Novick,Haya Ascher-Svanum,Josep Maria Haro et al.
Diego Novick et al.
Background: The purpose of this study was to assess the 12-month outcomes associated with naturalistic antipsychotic treatment of patients participating in the Schizophrenia Outpatient Health Outcomes (SOHO) study. ...
Gene L Colice
Gene L Colice
Asthma and chronic obstructive pulmonary disease (COPD) are common diseases which cause patients and society considerable difficulties. These are costly diseases which cause substantial morbidity and death. Health care policy makers have ma...
Discontinuation of low-dose acetylsalicylic acid therapy in UK primary care: incidence and predictors in patients with cardiovascular disease [0.03%]
英国初级保健中低剂量阿司匹林治疗的停药率及影响因素：心血管疾病患者中的发生率和预测指标
Elisa Martín-Merino,Saga Johansson,Héctor Bueno et al.
Elisa Martín-Merino et al.
Background: Discontinuation of low-dose acetylsalicylic acid (ASA) leads to an increased risk of cardiovascular and cerebrovascular events in patients taking low-dose ASA for secondary cardiovascular prevention. However, ...
Physicians' attitudes towards combination therapy with inhaled corticosteroids and long-acting β2-agonists: an observational study in UK specialist care [0.03%]
英国专科护理中吸入性皮质类固醇与长效β2受体激动剂联合治疗的态度：一项观察性研究
Mike Thomas,John Haughney,David Price
Mike Thomas
Purpose: Recent real-world studies have demonstrated that asthma control remains suboptimal in many patients. The aim of this study was to evaluate physicians' perceptions of the effectiveness of combination therapy with ...