Integrating Machine Learning With Microsimulation to Classify Hypothetical, Novel Patients for Predicting Pregabalin Treatment Response Based on Observational and Randomized Data in Patients With Painful Diabetic Peripheral Neuropathy [0.03%]
基于观察性和随机数据的机器学习与微观模拟相结合，根据 gabalin 治疗反应对假设的新患者进行分类以预测糖尿病外周神经病变患者的治疗效果
Joe Alexander Jr,Roger A Edwards,Luigi Manca et al.
Joe Alexander Jr et al.
Purpose: Variability in patient treatment responses can be a barrier to effective care. Utilization of available patient databases may improve the prediction of treatment responses. We evaluated machine learning methods t...
Prescription patterns of analgesics, antipyretics, and non steroidal anti-inflammatory drugs for the management of fever and pain in pediatric patients: a cross-sectional, multicenter study in Latin America, Africa, and the Middle East [0.03%]
用于儿科患者发热和止痛的镇痛药、解热药和非甾体抗炎药处方模式：拉丁美洲、非洲和中东多中心横断面研究
María Carolina Kamel Escalante,Abbas Abdennour,Antoine Farah et al.
María Carolina Kamel Escalante et al.
Objective: To evaluate the daily practice of pediatricians, physician-perceived reasons for unsatisfactory effects of treatment, and unmet needs in the management of acute pain and/or fever. ...
Management Of Community-Acquired Pneumonia: An Observational Study In UK Primary Care [0.03%]
英国初级保健中心社区获得性肺炎管理情况观察研究
Naomi Launders,Dermot Ryan,Christopher C Winchester et al.
Naomi Launders et al.
Purpose: In primary care, initial diagnosis of community-acquired pneumonia (CAP) is made on clinical judgment without radiological confirmation or knowledge of the causative organism. Use of CRB65 score has been recommen...
A multicenter, open-label, noninterventional study to evaluate the impact on clinical effects, user-friendliness and patients' acceptance of AirFluSal Forspiro in the treatment of asthma under real-life conditions (ASSURE) [0.03%]
一项多中心、开放标记、非干预性研究，在真实条件下评估AirFluSal Forspiro在哮喘治疗中的临床效果、使用便捷性和患者的接受程度（ASSURE）
Vibeke Backer,Leif Bjermer,Olav Kåre Refvem et al.
Vibeke Backer et al.
Background: The design of inhaler devices may potentially influence adherence/persistence and outcomes in asthma. Objective: The primary objective was to assess asthma control and any change in the quality of life in patients using an intui...
Casual effect of methotrexate+etanercept/infliximab on survival of patients with rheumatoid arthritis [0.03%]
甲氨蝶呤联合英夫利昔或依那西普对类风湿关节炎患者的生存效应研究
Saeed Akhlaghi,Maryam Sahebari,Mahmoud Mahmoodi et al.
Saeed Akhlaghi et al.
Background and objectives: Following the discovery of new drugs, physicians and pharmaceutical companies have become interested in examining patients' mortality and morbidity rates. In this respect, the effects of methotrexate (MTX)+etanerc...
Using claims data to attribute patients with breast, lung, or colorectal cancer to prescribing oncologists [0.03%]
利用索赔数据将乳腺癌、肺癌或结直肠癌患者归因于开具药物的肿瘤医生
Ezra Fishman,John Barron,Ying Liu et al.
Ezra Fishman et al.
Background: Alternative payment models frequently require attribution of patients to individual physicians to assign cost and quality outcomes. Our objective was to examine the performance of three methods for attributing...
The effect of lercanidipine or lercanidipine/enalapril combination on blood pressure in treatment-naïve patients with stage 1 or 2 systolic hypertension [0.03%]
勒卡奈地平或勒卡奈地平/依那普利联合治疗对1级或2级收缩期高血压初治患者的血压影响
Brian Rayner
Brian Rayner
Purpose: To describe the efficacy of a stratified approach on automatic office blood pressure (BP), 24-hour ambulatory BP, and BP variability (BPV) in treatment-naïve patients with systolic hypertension using lercanidipi...
Low-fluoroscopy atrial fibrillation ablation with contact force and ultrasound technologies: a learning curve [0.03%]
基于接触力和超声技术的低透视下房颤消融学习曲线研究
Paul C Zei,Tina D Hunter,Larry M Gache et al.
Paul C Zei et al.
Background: Fluoroscopy exposure during catheter ablation is a health hazard to patients and operators. This study presents the results of implementing a low-fluoroscopy workflow using modern contact force (CF) technologi...
Acute cholecystitis - a cohort study in a real-world clinical setting (REWO study, NCT02796443) [0.03%]
急性胆囊炎的队列研究：实际临床环境中的研究（REWO 研究，NCT02796443）
Jennifer Blythe,Eva Herrmann,Dominik Faust et al.
Jennifer Blythe et al.
Background: For decades, the optimal timing of surgery for acute cholecystitis has been controversial. Recent meta-analyses and population-based studies favor early surgery. One recent large randomized trial has demonstra...
Postoperative swallowing disorder after thyroid and parathyroid resection [0.03%]
甲状腺和甲状旁腺切除术后的术后吞咽障碍
Andreas Hillenbrand,Gregor Cammerer,Lisa Dankesreiter et al.
Andreas Hillenbrand et al.
Introduction: Dysphagia is frequently reported after thyroidectomy. Here, we investigated the incidence of postoperative dysphagia after uncomplicated thyroidectomy and parathyroidectomy. Further, we analyzed diagnosis an...