Development and Internal Validation of a Prediction Model for Major Cardiovascular and Respiratory Events in Chronic Obstructive Pulmonary Disease: Nationwide Primary Care Electronic Medical Records Cohort Study [0.03%]
Chris P Gale,Mohit Bhutani,Jeffrey Shi Kai Chan et al.
Chris P Gale et al.
Background: Cardiovascular diseases are prevalent in individuals with chronic obstructive pulmonary disease (COPD), but current cardiovascular risk assessment models are not optimised for COPD. We aimed to develop a predi...
Validity of Using Prescription Medications to Classify Disease - A Retrospective Observational Study Using Routinely Collected Electronic Health Records from the UK [0.03%]
基于英国电子健康记录的回顾性观察研究评估处方药分类疾病的有效性
Christian Schnier,John Busby,Aziz Sheikh et al.
Christian Schnier et al.
Background: Epidemiological studies rely on valid classifications of patients' disease status. However, in the absence of perfect information on every patients' health status, researchers use proxy information with variab...
Relapse Predictors of Idiopathic Retroperitoneal Fibrosis: A Long-Term Cohort Study [0.03%]
特发性后腹膜纤维化的复发预测因素：一项长期队列研究
Sicheng Huang,Anqi Wang,Yimeng Jia et al.
Sicheng Huang et al.
Objective: This study aims to identify predictive factors for the relapse of idiopathic retroperitoneal fibrosis (IRF) and provide instructions for the optimization of the maintenance therapy. ...
INSIGHTS Asthma Pragmatic Registry - A Pragmatic Approach to High-Validity Real-World Evidence for Asthma [0.03%]
INSIGHTS哮喘 pragmatic 注册研究——高可靠性的现实世界证据的务实方法（INSIGHTS哮喘注册研究）
Karynsa Kilpatrick,Urmila Chandran,Robert Urman et al.
Karynsa Kilpatrick et al.
Purpose: Asthma is a heterogenous disease, and up to 10% of asthma patients have severe disease. While critical, clinical trials in these patients are generally not representative of the broader ambulatory patient populat...
Derivation and Definitions of Clinical Study Variables for Multiple Long Term Conditions in Patients with Chronic Obstructive Pulmonary Disease: Protocol for a Modified Delphi Methods and Consensus Study on Behalf of the International Cardiovascular and Respiratory Alliance [0.03%]
慢性阻塞性肺疾病患者多重长期条件的临床研究变量的推导和定义：国际心血管和呼吸联盟委托的改良德尔菲法和共识研究报告方案
Tobin Joseph,Mohit Bhutani,Amy Couper et al.
Tobin Joseph et al.
Background: Standardized variables and their definitions are essential for robust delivery and reporting of clinical studies and quality improvement in chronic obstructive pulmonary disease (COPD). This protocol describes...
Evaluation of Disease Modifying Therapies and Prognostic Factors Affecting Multiple Sclerosis Progression in a Local Centre of Hong Kong [0.03%]
评估香港本地医疗中心的疾病修正治疗及影响多发性硬化进展的预后因素的影响
Bobby Chun Man Lui,Jessica Tsz Ching Li,Wai Ting Lo et al.
Bobby Chun Man Lui et al.
Introduction: Multiple sclerosis (MS) is a major demyelinating disease causing disability in young adults. Scarce data exists on the clinical benefits and persistence of disease modifying therapies (DMTs) amongst our loca...
One Year Risk Prediction Model for Cardiovascular Disease for Adults with Asthma in England [0.03%]
英国成人哮喘患者一年内心血管疾病风险预测模型
Jessica Baskaran,Vesselin A Novov,Jennifer K Quint et al.
Jessica Baskaran et al.
Background: Cardiovascular disease (CVD) continues to be a significant health threat to humans globally, and a significant burden on healthcare systems. Cardiovascular risk prediction utilizing machine learning (ML) model...
Real-World Treatment Patterns and Overall Survival (OS) of Patients with Metastatic Castration-Resistant Prostate Cancer in Italy [0.03%]
意大利转移性去势抵抗性前列腺癌患者的现实世界治疗模式和总生存期(OS)研究
Melania Dovizio,Daniela Castelletti,Paolo Luraghi et al.
Melania Dovizio et al.
Purpose: This real-world analysis described the characteristics and therapeutic management of patients with metastatic castration-resistant prostate cancer (mCRPC) in Italy before and after 2015, when androgen receptor si...
Clinical Outcomes of Ablation for Persistent Atrial Fibrillation with Zero or Minimal Fluoroscopy [0.03%]
零或最小剂量放射引导下持续性房颤射频消融的临床疗效研究
Jose Osorio,Gustavo Morales,Anil Rajendra et al.
Jose Osorio et al.
Purpose: Recent developments in electroanatomical mapping (EAM), intracardiac echocardiography, and sheath technology have allowed for a pronounced reduction or complete elimination of fluoroscopy during catheter ablation...
Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM [0.03%]
专家视角：下一代卫生指导原则的意见征集——如何在以证据为基础的医疗中融合真实世界证据
Stefano Del Giacco,Giorgio Walter Canonica,Ioana Agache et al.
Stefano Del Giacco et al.
Integrating real-world evidence (RWE) into evidence-based medicine (EBM) enhances healthcare decision-making. RWE provides insights into the real-world effectiveness and safety of therapies and health technologies, filling gaps that clinica...