Analysis of Mitogen-Activated Protein Kinases in Bone and Cartilage of Patients with Rheumatoid Arthritis Treated with Abatacept [0.03%]
阿巴西普治疗类风湿关节炎患者骨和软骨中MAPKs的分析研究
Katsuaki Kanbe,Koei Oh,Junji Chiba et al.
Katsuaki Kanbe et al.
The aim of this study was to analyze the histological changes related to mitogen-activated protein (MAP) kinases in bone and cartilage treated with abatacept for rheumatoid arthritis (RA). A total of 20 patients of bone and cartilage were a...
Simultaneous Treatment with Subcutaneous Injection of Golimumab and Intra-articular Injection of Triamcinolone Acetonide (K-Method) in Patients with Rheumatoid Arthritis Undergoing Switching of Biologics: Retrospective Case-Control Study [0.03%]
接受生物制剂转换的类风湿关节炎患者同时使用戈利木单抗皮下注射和曲安奈德关节内注射（K方案）治疗：病例对照研究
Katsuaki Kanbe,Junji Chiba,Yasuo Inoue et al.
Katsuaki Kanbe et al.
Background: Tight control of severe rheumatoid arthritis (RA) in patients with high disease activity, even when using biologics, is sometimes difficult using a treat-to-target strategy. Switching from one biologic to anot...
Reduction in Serum Uric Acid May Be Related to Methotrexate Efficacy in Early Rheumatoid Arthritis: Data from the Canadian Early Arthritis Cohort (CATCH) [0.03%]
早期类风湿关节炎患者血尿酸降低与甲氨蝶呤疗效之间的关系：来自加拿大早期 arthritis 队列研究(CATCH)的数据分析
Jason J Lee,Vivian P Bykerk,George K Dresser et al.
Jason J Lee et al.
Objectives: The mechanism of action of methotrexate in rheumatoid arthritis (RA) is complex. It may increase adenosine levels by blocking its conversion to uric acid (UA). This study was done to determine if methotrexate ...
Serum and Urinary Interleukin-6 in Assessment of Renal Activity in Egyptian Patients with Systemic Lupus Erythematosus [0.03%]
评估系统性红斑狼疮患者肾损害活动性的血清及尿IL-6检测研究
Rawhya R El-Shereef,Ahmed Lotfi,Emad A Abdel-Naeam et al.
Rawhya R El-Shereef et al.
Aim of the work: This study investigates whether serum and urinary interleukin-6 (IL-6) represent an early marker of kidney involvement and assesses the difference between them and renal biopsy in lupus nephritis (LN). ...
Clinicians' Perspectives on the Use of Intra-Articular Hyaluronic Acid as a Treatment for Knee Osteoarthritis: A North American, Multidisciplinary Survey [0.03%]
北美地区临床医生应用透明质酸治疗膝关节骨关节炎的多学科调查研究：关于其疗效与安全性的临床观点
Jeffrey Rosen,Victoria Avram,Anke Fierlinger et al.
Jeffrey Rosen et al.
Introduction: This study aims to describe the perceptions of orthopedic surgeons on the efficacy of intra-articular hyaluronic acid (IA-HA), the influence of IA-HA product characteristics on its efficacy, and to identify ...
Ochronotic Arthropathy: Two Case Reports from a Developing Country [0.03%]
ochronosis关节病：来自发展中国家的两例报告
Farooq A Rathore,Saeed B Ayaz,Sahibzada N Mansoor
Farooq A Rathore
Alkaptonuria is a rare inborn error of metabolism, which is classified as an orphan disease. It is due to the lack of an enzyme homogentisate 1,2-dioxygenase, which results in an accumulation of homogentisic acid in different areas of the b...
Mechanisms Involved in Toxicity of Liver Caused by Piroxicam in Mice and Protective Effects of Leaf Extract of Hibiscus rosa-sinensis L [0.03%]
牻牛儿苗叶提取物对吡罗昔康所致小鼠肝毒性的保护作用及机制研究
C R Sahu
C R Sahu
Piroxicam is one of the important therapeutic nonsteroidal anti-inflammatory class of drugs used mainly to suppress pain and inflammation in arthritis and other musculoskeletal disorders. Besides being anti-inflammatory, these drugs are ana...
Clinical Features of Neuropsychiatric Syndromes in Systemic Lupus Erythematosus and Other Connective Tissue Diseases [0.03%]
系统性红斑狼疮及其他结缔组织病的神经精神临床特征
Tsuyoshi Kasama,Airi Maeoka,Nao Oguro
Tsuyoshi Kasama
Systemic lupus erythematosus (SLE) and related disorders are chronic inflammatory diseases characterized by abnormalities and, in some cases, even complete failure of immune responses as the underlying pathology. Although almost all connect...
Osteolysis Affecting the Jaws in Systemic Sclerosis: Clinical and Osseous Changes Based on a Case Presentation [0.03%]
系统性硬化病患者影响颌骨的骨溶解：基于病例报告的临床和骨骼变化
A Delantoni,E Matziari
A Delantoni
Objectives: The aim of the current paper is to present a case of systemic sclerosis of the jaws with all the characteristics and some extensive findings. ...
Role of Physical Evaluation in the Early Identification of Axial Spondyloarthritis: A Research Proposal [0.03%]
物理检查在轴向脊柱关节炎早期识别中的作用：一项研究提案
Marcelo P Castro,Simon M Stebbings,Stephan Milosavljevic et al.
Marcelo P Castro et al.
The aim of this study was to present a rationale to explore the use of clinical tests for the sacroiliac joints to detect early axial spondyloarthritis (SpA) and to suggest a protocol to validate these clinical tests. Based on the European ...