A randomized study comparing chemotherapy followed by G-CSF alone or in combination with GM-CSF for mobilization of peripheral blood stem cells in patients with non-Hodgkin's lymphomas [0.03%]
比较化疗后单用G-CSF或与GM-CSF合用动员非霍奇金淋巴瘤患者外周血干细胞的随机研究
Chitra Hosing,Mark F Munsell,James M Reuben et al.
Chitra Hosing et al.
Objective: Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) are the two most commonly used cytokines for mobilization of stem cells in patients undergoing high do...
Critical appraisal of the role of recombinant activated factor VII in the treatment of hemophilia patients with inhibitors [0.03%]
重组活化凝血因子VII在血友病伴抑制物患者治疗中作用的再评价
Ampaiwan Chuansumrit,Pantep Angchaisuksiri,Nongnuch Sirachainan
Ampaiwan Chuansumrit
Hemophilia patients with inhibitors faced the constraint of inadequate treatment for several years before the era of recombinant factor VIIa (rFVII). Initially, rFVIIa was used in the compassionate-use programs. After a worldwide license wa...
Serena Marotta,Pierpaolo Di Micco
Serena Marotta
Solitary plasmacytoma may be considered as a rare neoplasm of head and neck and is a different disease compared to multiple myeloma. The main difference is related to the better clinical prognosis of solitary plasmacytoma, which may be clin...
A review of immune thrombocytopenic purpura: focus on the novel thrombopoietin agonists [0.03%]
免疫性血小板减少性紫癜综述——新型促血小板生成素激动剂疗法聚焦
Meaghan Khan,Joseph Mikhael
Meaghan Khan
Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that is characterized by antibody-mediated platelet destruction and decreased platelet production. ITP and its treatments have been recognized to cause diminished quality of li...
Chang H Kim
Chang H Kim
Extramedullary hematopoiesis (EH) is defined as hematopoiesis occurring in organs outside of the bone marrow; it occurs in diverse conditions, including fetal development, normal immune responses, and pathological circumstances. During feta...
Maristella DUva,Pierpaolo Di Micco,Ida Strina et al.
Maristella DUva et al.
In recent decades, the association between a hypercoagulable state and its causes and adverse pregnancy outcome, in particular recurrent pregnancy loss (RPL) has been studied extensively. Although the first studies were focused only on the ...
The role of ofatumumab in the treatment of chronic lymphocytic leukemia resistant to previous therapies [0.03%]
奥法木单抗在既往治疗复发的慢性淋巴细胞性白血病中的作用
Jorge Castillo,Kimberly Perez
Jorge Castillo
Chronic lymphocytic leukemia (CLL) is an indolent but incurable disease. Despite the improvement of the available therapies, the management of heavily-treated CLL patients represents a challenge for modern practitioners. Ofatumumab is a sec...
Richard C Jin,Joseph Loscalzo
Richard C Jin
Nitric oxide (NO) is a structurally simple, highly versatile molecule that was originally discovered over 30 years ago as an endothelium-derived relaxing factor. In addition to its vasorelaxing effects, NO is now recognized a key determinan...