Baseline CD4+/CD8+ TEMRA Levels and Early Response Predict Survival After Umbilical Cord-Derived Mesenchymal Stem Cells Infusion in Acute GVHD Patients: A Randomized Double-Blinded Placebo-Controlled Multicentre Clinical Trial [0.03%]
基线时的CD4+/CD8+TEMRA水平及早期反应能够预测急性GVHD患者脐带来源间充质干细胞输注后的生存情况：一项随机双盲安慰剂对照多中心临床试验
Sze-Piaw Chin,Sen Mui Tan,Kian Meng Chang et al.
Sze-Piaw Chin et al.
Background: A major challenge after allogeneic haematopoietic stem cell transplantation for haematologic malignancies is the management of acute graft-versus-host disease (aGVHD), which remains associated with poor progno...
Clinical Trial
Journal of blood medicine. 2025 Oct 8:16:469-481. DOI:10.2147/JBM.S546632 2025
Erythrocyte Alloimmunization and Transfusion Strategies in Sickle Cell Disease: A Single-Center Analysis [0.03%]
输血策略和红细胞自身免疫在镰状细胞疾病中的影响：单中心分析
Abdulaziz Yusuf,Abrar Ahmad,Hesham A El-Beshbishy et al.
Abdulaziz Yusuf et al.
Aim: Alloimmunization (the production of antibodies against foreign red blood cell (RBC) antigens) is a significant complication in patients with sickle cell disease (SCD) who require chronic transfusion. This retrospecti...
Safety of Recombinant von Willebrand Factor in the Treatment of von Willebrand Disease: Real-World Data from an EU Post-Authorization Safety Study [0.03%]
重组血管性血友病因子治疗血管性血友病的现实世界安全性：欧盟上市后安全研究数据
Susan M Sinclair,Yi Ba,Kayode Badejo
Susan M Sinclair
Introduction: In Europe, recombinant von Willebrand factor (rVWF) is approved for the prevention and treatment of hemorrhage or surgical bleeding in adults with von Willebrand disease (VWD) for whom desmopressin alone is ...
Non-Traumatic Fat Embolism Syndrome in Two HbSS Sickle Cell Disease Patients: A Case Series and Review [0.03%]
两例非创伤性脂肪栓塞综合征的HbSS型镰状细胞病患者：病例系列及文献回顾
Mohammed Amouri Alzayer,Salah Abohelaika,Mousa Alhaddad et al.
Mohammed Amouri Alzayer et al.
Non-traumatic fat embolism syndrome (FES) in sickle cell disease (SCD) is associated with high morbidity and mortality. This severe complication arises from bone marrow necrosis, which subsequently can lead to fat embolism syndrome and mult...
Iron Overload and Its Impact on Liver Function and Lipid Profiles in Transfusion-Dependent β-Thalassemia Patients in Sana'a City [0.03%]
铁过载对萨那血 transfusion-dependent β-地中海贫血患者肝功能和脂质轮廓的影响
Ali Al-Shami,Mokhtar Alzomor
Ali Al-Shami
Background: β-thalassemia major (βTM) is a severe genetic blood disorder that necessitates regular blood transfusions, which often lead to iron overload and associated complications, including liver dysfunction and dysl...
Journeying Towards Excellence in the Care of Patients with Haemophilia and Other Inherited Bleeding Disorders From a Developing World: Insights From Tanzania [0.03%]
来自发展中国家的血友病和其他遗传性出血性疾病患者的护理迈向卓越之路——坦桑尼亚的经验教训
Stella Samson Rwezaula,Samson D Mtoba,Rashid A Gosse et al.
Stella Samson Rwezaula et al.
Introduction: Haemophilia, an X-linked recessive bleeding disorder caused by mutations in the F8 and F9 genes, remains profoundly underdiagnosed in resource-limited settings. In Tanzania, it is estimated that fewer than 1...
Multifaceted Clinical Spectrum of Vitamin B12 Deficiency - a Case Report and Literature Review [0.03%]
维生素B12缺乏的临床多样性——一例报告及文献复习
Ewa Pustelnik,Katarzyna Pikora,Magdalena Zofia Hartman et al.
Ewa Pustelnik et al.
Background: Vitamin B12 (cobalamin) deficiency is a well-known cause of hematologic and neurological disorders; however, its presentation can be highly variable, leading to diagnostic challenges. The etiology is diverse: ...
Greater Efficacy of Cidofovir Than of Foscarnet for the Treatment of Acyclovir-Resistant Herpes Simplex Virus Infection After Allogeneic Hematopoietic Stem Cell Transplantation [0.03%]
allo-HSCT后aciclovir耐药HSV感染的治疗效果：cidofovirus疗效优于foscarne FString
Jun Kong,Bin Chen,Yilei Ma et al.
Jun Kong et al.
Herpes simplex virus (HSV) infection is a common problem in patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Severe HSV infections can cause pneumonia, encephalitis, meningitis and other lesions, thus requiring...
First Report of Hematopoietic Stem Cell Transplantation for Children Diagnosed with Wiskott-Aldrich Syndrome in Vietnam [0.03%]
越南儿童WAS综合征患者的首例造血干细胞移植报告
Le Nguyen-Ngoc-Quynh,Binh Nguyen-Thanh,Anh Thi Van Nguyen et al.
Le Nguyen-Ngoc-Quynh et al.
Background: Awareness of inborn error immunity, such as Wiskott-Aldrich syndrome (WAS), is still lacking in Vietnam. The shortage of clinical immunologists and transplantation teams lead to poor prognosis for patients. ...
Exploring the Relationship Between Personalization of Care and Participation in Sport Activities Among People with Severe Hemophilia A Across Europe: Post Hoc Analysis of the CHESS II Study [0.03%]
欧洲严重甲型血友病患者护理个性化与参与体育活动之间的关系：CHESS II研究的事后分析
Tom Blenkiron,Enrico Ferri Grazzi,Tom Burke et al.
Tom Blenkiron et al.
Purpose: To describe the demographic and clinical characteristics of patients with hemophilia A receiving different levels of treatment personalization (TP), and to assess the relationship between TP and sport active time...