Clinical outcomes following advanced respiratory motion management (respiratory gating or dynamic tumor tracking) with stereotactic body radiation therapy for stage I non-small-cell lung cancer [0.03%]
立体定向体部放射治疗一期非小细胞肺癌采用高级呼吸运动管理（呼吸门控或动态病灶跟踪）的临床疗效分析
Paul Aridgides,Tamara Nsouli,Rishabh Chaudhari et al.
Paul Aridgides et al.
Purpose: To report the outcomes of stereotactic body radiation therapy (SBRT) for stage I non-small-cell lung cancer (NSCLC) according to respiratory motion management method. ...
Prophylactic cranial irradiation in small-cell lung cancer: update on patient selection, efficacy and outcomes [0.03%]
小细胞肺癌预防性颅脑照射的患者选择、疗效和结局更新分析
Farkhad Manapov,Lukas Käsmann,Olarn Roengvoraphoj et al.
Farkhad Manapov et al.
Over 10% of small-cell lung cancer (SCLC) patients have brain metastases (BM) at initial diagnosis; more than 50% will develop BM within 2 years. BM are detected in up to 80% of all patients at autopsy. After primary treatment, prophylactic...
Amifostine- and chemoradiotherapy-related esophagitis in small cell lung cancer: a single institutional series and literature update [0.03%]
氨磷汀和放化疗所致的小细胞肺癌食管炎：单中心系列研究及文献更新
Ariel E Pollock,Lowell Shinn,Richard Anderson et al.
Ariel E Pollock et al.
Objectives: Concurrent chemoradiotherapy is considered a standard option for patients with stage 3 small cell lung carcinoma. A 25% risk of acute esophagitis is experienced by patients as a result of the volume of esophag...
Hypersensitivity in ALK-positive lung cancers exposed to ALK inhibitors: a case of successful switch to an alternative ALK inhibitor and systematic review of the literature [0.03%]
ALK阳性肺癌接受ALK抑制剂治疗后出现的高敏反应：成功换用另一种ALK抑制剂的病例及文献系统综述
Lei Deng,Janaki Sharma,Elizabeth Ravera et al.
Lei Deng et al.
Alectinib can cause rare, but severe hypersensitivity. The cross-reactivity between different ALK inhibitors is unknown and desensitization is the only reported management. We hereby report the first case of severe delayed hypersensitivity ...
1-, 3-, and 5-year survival among early-stage lung cancer patients treated with lobectomy vs SBRT [0.03%]
早期肺癌患者接受肺叶切除术与立体定向放疗的生存情况比较研究
Denise Albano,Thomas Bilfinger,Barbara Nemesure
Denise Albano
Background: Lobectomy has traditionally been recommended for fit patients diagnosed with early-stage non-small-cell lung cancer (NSCLC). Recently, however, stereotactic body radiotherapy (SBRT) has been introduced as an a...
Luisa María Ricaurte,Oscar Arrieta,Zyanya Lucia Zatarain-Barrón et al.
Luisa María Ricaurte et al.
Fetal adenocarcinoma of the lung (FLAC) is a rare tumor. It accounts for ~0.1%-0.5% of all pulmonary neoplasms. Due to its rarity, much of the world literature regarding FLAC comes from case reports and case series. FLAC is an adenocarcinom...
Response to rapamycin analogs but not PD-1 inhibitors in PTEN-mutated metastatic non-small-cell lung cancer with high tumor mutational burden [0.03%]
PTEN突变型高肿瘤突变负荷转移性非小细胞肺癌对雷帕霉素类似物而非PD-1抑制剂的反应
Ankur R Parikh,Siraj M Ali,Alexa B Schrock et al.
Ankur R Parikh et al.
In non-small-cell lung cancer (NSCLC) refractory to standard therapy and which lacks well-known oncogenic drivers, genomic profiling can still identify genomic alterations that may suggest potential sensitivity to targeted therapy. PTEN mut...
Eloise Mastrangelo,Mario Milani
Eloise Mastrangelo
GLI1 is a transcriptional regulator involved in the development of different types of cancer. GLI1 transcriptional activity is regulated within the Hedgehog pathway (canonical activity), but can also be controlled independently (non-canonic...
Uncommon EGFR mutations in cytological specimens of 1,874 newly diagnosed Indonesian lung cancer patients [0.03%]
印度尼西亚1874例新诊断肺癌患者细胞学标本中不常见的EGFR突变
Elisna Syahruddin,Laksmi Wulandari,Nunuk Sri Muktiati et al.
Elisna Syahruddin et al.
Purpose: We aimed to evaluate the distribution of individual epidermal growth factor receptor (EGFR) mutation subtypes found in routine cytological specimens. ...
Stereotactic body radiation therapy (SBRT) in the management of non-small-cell lung cancer: Clinical impact and patient perspectives [0.03%]
立体定向体部放射治疗（SBRT）在非小细胞肺癌管理中的临床影响和患者观点
Elysia K Donovan,Anand Swaminath
Elysia K Donovan
Stereotactic body radiation therapy (SBRT) has emerged as a new technology in radiotherapy delivery, allowing for potentially curative treatment in many patients previously felt not to be candidates for radical surgical resection of stage I...