Joachim Peitz,Gerd Horneff
Joachim Peitz
Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the availability of cytokine antagonists targeting interleukin-1 and interleukin-6 have markedly advanced the therapeutic options. In this review, we focus on the...
Unique aspects of pain reduction in osteoarthritis of the knee with LMWF-5A [0.03%]
低分子量透明质钠(LMWHA-F5A)治疗膝骨关节炎镇痛作用的特点研究
Brian McGrath
Brian McGrath
Osteoarthritis of the knee (OAK) is a common form of arthritis that can lead to substantial pain and disability. This commentary highlights key aspects of the recently published phase 3 A Efficacy and Safety Study of Two Doses of Intra-Arti...
Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone [0.03%]
膝骨关节炎关节腔注射疗效的前瞻性随机研究:透明质酸与倍他米松的比较
Cesáreo Ángel Trueba Davalillo,Cesáreo Trueba Vasavilbaso,José Mario Navarrete Álvarez et al.
Cesáreo Ángel Trueba Davalillo et al.
Background: Osteoarthritis (OA) is the most common joint disease and leading cause of disability. Intra-articular (IA) administration of hyaluronic acid (HA) or corticosteroids (CS) have been previously studied, though us...
Ryo Rokutanda,Mitsumasa Kishimoto,Masato Okada
Ryo Rokutanda
Behçet's disease is a multi-organ disorder that is more common in countries around the Silk Road, and manifests as mucosal ulcers and skin lesions, and with ocular involvement. As a systemic disease, it can also involve gastrointestinal or...
Efficacy of a natural mineral complex in North American adults with osteoarthritis of the knee: a randomized double-blind placebo-controlled study [0.03%]
北美膝关节骨关节炎患者服用天然矿物 комплекс的有效性:随机双盲对照研究
Malkanthi Evans,Dale Wilson,Najla Guthrie
Malkanthi Evans
Purpose: This study evaluated the efficacy of a hydrothermal mineral complex (HMC) supplement in participants with knee osteoarthritis. Patients and metho...
Efficacy and safety of adalimumab in ankylosing spondylitis [0.03%]
阿达木单抗治疗强直性脊柱炎的疗效和安全性评估:一项随机、双盲、安慰剂对照试验
Aziza Mounach,Abdellah El Maghraoui
Aziza Mounach
Ankylosing spondylitis (AS) is the most common and most severe subtype of spondyloarthritis. It also may be an outcome of any of the other spondyloarthritis subtypes. AS preferentially affects the sacroiliac joints and the tip of the column...
Carol M Artlett
Carol M Artlett
Without doubt, animal models have provided significant insights into our understanding of the rheumatological diseases; however, no model has accurately replicated all aspects of any autoimmune disease. Recent years have seen a plethora of ...
Serum anticyclic citrullinated protein antibody titers are correlated with the response to biological agents in patients with rheumatoid arthritis [0.03%]
抗环瓜氨酸肽抗体滴度与类风湿关节炎患者对生物制剂的反应相关性研究
Ryo Takahashi,Sakiko Isojima,Masayu Umemura et al.
Ryo Takahashi et al.
Anticyclic citrullinated protein antibody (ACPA) is known as an important indicator for diagnosis of rheumatoid arthritis (RA). Our aim was to examine the relationship between the serum ACPA titer at baseline and responsiveness to biologica...
Use of ibuprofen sustained release for treating osteoarthritic pain: findings from 15 general medical practices in Egypt [0.03%]
布洛芬缓释制剂治疗骨关节炎疼痛的临床研究
Nabil Khalifa,Timour El-Husseini,Ahmed Morrah et al.
Nabil Khalifa et al.
Purpose: Ibuprofen sustained release (SR) has been shown to provide effective symptomatic pain relief in chronic arthritic conditions such as osteoarthritis in European and US patient populations. Few studies have been co...
José Luis Rosales-Alexander,Jerónimo Balsalobre Aznar,César Magro-Checa
José Luis Rosales-Alexander
Calcium pyrophosphate dihydrate crystal deposition disease (CPPD) is an inflammatory arthritis produced by the deposition of calcium pyrophosphate (CPP) crystals in the synovium and periarticular soft tissues. It is the third most common in...