AC067930.4/miR-375 Axis Regulates the Malignant Progression of Colon Adenocarcinoma Through the Cuproptosis-Related Gene SLC6A6 [0.03%]
AC067930.4/miR-375轴通过铜依赖性细胞死亡相关基因SLC6A6调控结肠腺癌恶性进展
Bin Hou,Qiang Liu,Zhi Li
Bin Hou
Background: Colon adenocarcinoma (COAD) is associated with high incidence rates and poor prognosis. LncRNAs and microRNAs are known to regulate COAD progression via the competing endogenous RNA (ceRNA) mechanism. Cupropto...
A Review of the Role and Mechanism of GNG4 Gene Expression in the Tumor Microenvironment Across Broad Spectrum of Tumor Types [0.03%]
GNG4基因在肿瘤类型广谱中的肿瘤微环境作用与机制综述
Shuang Liu,Shuang Zheng,Xi Yu et al.
Shuang Liu et al.
DNA methylation is a common and very important type of epigenetic modification, and its changes often occur in cancer and are highly dysregulated. Guanine Nucleotide binding-protein Gamma subunit 4 (GNG4), as a key component of the G protei...
Clinical Efficacy and Security Analysis of CDK4/6 Inhibitors Combined with ET in Patients with HR+HER2- Advanced Breast Cancer [0.03%]
Cyclin依赖性激酶4/6抑制剂联合内分泌治疗HR阳性HER2阴性晚期乳腺癌患者的临床疗效及安全性分析
Yan Wang,Dongmei Chen,Zhenning Wang et al.
Yan Wang et al.
Objective: To evaluate the clinical efficacy and security of CDK4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) in patients with hormone receptor-positive (HR⁺), human epidermal growth factor receptor 2-neg...
Safety and Clinical Outcomes of Kanglaite Injection in Combination with Toripalimab and Chemotherapy for Advanced Non-Small Cell Lung Cancer: A Real-World Retrospective Analysis [0.03%]
康莱特注射液联合特瑞普利单抗和化疗治疗晚期非小细胞肺癌的安全性及临床疗效:真实世界回顾分析
Riwen Zhang,Zicong Feng,Xiaozhou Pan et al.
Riwen Zhang et al.
Introduction: For advanced non-small cell lung cancer (NSCLC) without oncogenic drivers, PD-1 inhibitors combined with chemotherapy represent a standard first-line regimen. However, treatment-related adverse events (TRAEs...
Impact of Evolving Antiemetic Prophylaxis on Chemotherapy-Induced Nausea and Vomiting (CINV): A Five-Year Comparative Study in Sichuan, China (2018-2023) [0.03%]
不断变化的止吐预防措施对中国四川化疗引起的恶心和呕吐(CINV)的影响:一项为期五年的比较研究(2018-2023)
Weijie Xiong,Weiwei Zhang,Quande Zhao et al.
Weijie Xiong et al.
Background: A baseline study conducted in 2018 revealed suboptimal guideline adherence and high chemotherapy-induced nausea and vomiting (CINV) burden in Sichuan, China. Since then, concerted efforts have been made to enh...
Optimizing Left-Sided Breast Cancer Radiotherapy: Strategy-Dependent Trade-Offs Among VMAT and Hybrid Techniques [0.03%]
左侧乳腺癌放疗的优化:VMAT与混合技术的策略依赖性权衡
Rocco Mottareale,Francesca Buonanno,Valentina dAlesio et al.
Rocco Mottareale et al.
Purpose: To compare dosimetric trade-offs among two full-VMAT and two hybrid 3D-CRT/VMAT strategies for left-sided whole-breast irradiation (WBI), and to evaluate the influence of planning strategy, introducing a novel ta...
The Luo-Dingyuan Thyroid Vascular-Lymphatic Segmentation Classification: A Functional Anatomy-Based Framework to Facilitate Precision Management and Thyroid Function Preservation [0.03%]
罗定远甲状腺血管淋巴分区分类法:一种促进精准诊疗和保护甲状腺功能的功能解剖学框架
Dingyuan Luo
Dingyuan Luo
Background: Hypothyroidism remains a common and clinically significant consequence of thyroid surgery, frequently necessitating long-term or lifelong thyroid hormone replacement therapy, which may be associated with adver...
Mobile Health (mHealth) Technology for Early Detection of Psychosocial Distress in Cancer Patients: A Scoping Review [0.03%]
癌症患者的移动健康(mHealth)技术在心理社会压力早期检测中的作用:系统综述
Taty Hernawaty,Suryani Suryani,Ida Maryati et al.
Taty Hernawaty et al.
Background: Psychosocial screening is the systematic identification of psychological and social problems in cancer patients, including emotional distress, anxiety, and depression. Mobile health (mHealth) technology has th...
CircCDK6 Regulates Stemness Maintenance and Cisplatin Resistance in Lung Adenocarcinoma via the Wnt/β-Catenin Signaling Pathway [0.03%]
circCDK6通过Wnt/β-catenin信号通路调控肺癌腺癌干细胞特性维持及顺铂耐药性
Dan Li,Yanwei Shen,Li Wang et al.
Dan Li et al.
Objective: This study investigates the role of circCDK6 in maintaining cancer stem cell (CSC) properties and mediating cisplatin resistance in lung adenocarcinoma (LUAD), with a focus on the involvement of the Wnt/β-cate...
Factors Influencing Survival After Curative Gastrectomy in Oligometastatic Gastric Cancer: A Single-Center Study [0.03%]
影响寡转移胃癌根治术生存因素的单中心研究
Merve Yumak,Abdulkadir Deniz,Gokturk Gursoy
Merve Yumak
Background: Gastric cancer remains a major global health burden. Oligometastatic gastric cancer (OMGC) represents an intermediate disease state with limited metastatic spread and potential eligibility for multimodal treat...