Haploidentical Allogeneic Cell Transplantation in Relapsed/Refractory Multiple Myeloma [0.03%]
haploidentical 同种异体细胞移植在复发和难治性多发性骨髓瘤中的应用
Julia Frimmel,Anke Morgner,Claudia Brogsitter et al.
Julia Frimmel et al.
Purpose: Although emerging therapies for multiple myeloma (MM) have improved treatment options, long-term disease control in relapsed/refractory (r/r) MM remains a challenge. While the effect of natural killer cell allore...
Clinicopathological Features and Prognostic Differences Between Primary and Relapsed or Refractory Extramedullary Multiple Myeloma [0.03%]
原发性与复发/难治性髓外多发性骨髓瘤的临床病理特征及预后差异分析
Xiumei Hu,Meng Yang,Yanan Qi et al.
Xiumei Hu et al.
Purpose: This study aims to explore the clinicopathological features related to extramedullary multiple myeloma (EMM) occurrence and evaluate prognosis differences between patients with primary EMM (PEMM) and those with r...
Mindfulness, Psychological Resilience, and Social Function Deficits in Young and Middle-Aged Lymphoma Patients: A Latent Profile and Mediation Analysis [0.03%]
正念、心理韧性与青年及中年淋巴瘤患者的社会功能缺陷：潜在类别分析和中介作用分析
Li Zhang,Fengyi Li,Yaru Wu et al.
Li Zhang et al.
Objective: This study aims to identify distinct mindfulness profiles among young and middle-aged lymphoma patients and to examine the mediating role of psychological resilience in the relationship between these mindfulnes...
Prediction of Prostate Adenocarcinoma Recurrence Prognosis and Immune Status Through 6-Acetoxy-Anopterine Resistance-Associated Programmed Cell Death Genes [0.03%]
通过6-乙酰氧基-安诺特林抗性相关程序性细胞死亡基因预测前列腺腺癌复发预后及免疫状态
Jie Cheng,Dongdong Mao
Jie Cheng
Purpose: This study aims to reveal the potential mechanism and potential prognostic markers of programmed cell death (PCD) genes associated with 6-acetoxy-anopterine (6-AA) resistance in prostate adenocarcinoma (PRAD). ...
Six-Transmembrane Epithelial Antigen of the Prostate 1 Promotes HCC Proliferation and Metastasis in vitro and in vivo via the Wnt/β-Catenin Signaling Pathway [0.03%]
六跨膜上皮前列腺抗原1通过Wnt/β-catenin信号通路促进肝癌的体内外增殖和转移
Haichao Liu,Jie Gao,Xudong Liu et al.
Haichao Liu et al.
Objective: To investigate the role and underlying mechanism of Six-Transmembrane Epithelial Antigen of the Prostate 1 (STEAP1) in Hepatocellular carcinoma (HCC) progression, and to validate its potential as a therapeutic ...
Fatal Disease Progression Driven by Acquired MET Amplification After EGFR-TKI Therapy in EGFR- and RBM10-Mutant Lung Adenocarcinoma [0.03%]
表皮生长因子受体和RBM10基因突变的肺腺癌患者在服用表皮生长因子受体酪氨酸激酶抑制剂后出现获得性MET扩增导致病情进展为致命性疾病
Jiwon Kim,Kiyong Na,Seung Hyeun Lee
Jiwon Kim
Although mesenchymal-epithelial transition proto-oncogene (MET) amplification is a common resistance mechanism in targeted therapy for lung cancer, rapid disease progression associated with this resistance mechanism in patients with epiderm...
Effectiveness of Neck Lymph Node Dissection for Breast Cancer Patients with Isolated Supraclavicular Nodal Recurrence [0.03%]
孤立性锁骨上淋巴结复发乳腺癌患者的颈淋巴结清扫效果分析
Hiroshi Isozaki,Yasuhisa Yamamoto,Shigeki Murakami et al.
Hiroshi Isozaki et al.
Background: Isolated supraclavicular nodal recurrence (ISNR) is a rare form of recurrence and is regarded as a precursor of a poor prognosis. The surgical removal of ISNR is typically neglected in multimodal therapy. ...
Circulating Tumor Cell PD-L1 and Peripheral Blood CD8+ T-Cell PD-1 as Dual Liquid Biopsy Biomarkers for Immunotherapy Outcomes in Advanced Non-Small Cell Lung Cancer: A Retrospective Study [0.03%]
循环肿瘤细胞PD-L1和外周血CD8+T细胞PD-1作为晚期非小细胞肺癌免疫治疗效果的双重液体活检标志物：一项回顾性研究
Shuhong Guan,Junkang Huangfu,Xiaoqin Zhu et al.
Shuhong Guan et al.
Background: Circulating tumor cells (CTCs) and peripheral T-cell immune checkpoints offer minimally invasive biomarkers for immune checkpoint inhibitor (ICI) therapy. We assessed whether a dual biomarker combining PD-L1 o...
Saikosaponin D Induced Apoptosis and Anti-Tumor Effect Enhancing Chemotherapy Sensitivity of Gemcitabine in Patient-Derived Cholangiocarcinoma Organoids [0.03%]
飞赛草皂苷D诱导胆管癌器官类器官瘤细胞凋亡及增敏吉西他滨化疗作用研究
Bing Han,Guoqiang Xing,Kunkun Du et al.
Bing Han et al.
Background: Cholangiocarcinoma (CCA), an aggressive malignancy with limited therapeutic options and poor survival rates, poses an urgent clinical challenge necessitating innovative therapeutic strategies. Saikosaponin D (...
Research Progress on Copper Metabolism, Cuprotosis, and Their Regulatory Mechanism in Tumor Diagnosis and Treatment [0.03%]
铜代谢、铜死亡与肿瘤诊治的调控机制研究进展
Rui Wang,Fei Wang,Yuting Xu et al.
Rui Wang et al.
A co-factor of multiple metalloenzymes that promote normal physiological functions, such as the immune system, neurological system, human hematological function, bone health, and antioxidant action, copper is one of the most important trace...