Interventional Management of Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus and Secondary Deep Venous Thrombosis: A Case Report [0.03%]
Junde Liu,Kai He,Zhonghua Luo et al.
Junde Liu et al.
Renal cell carcinoma (RCC) with inferior vena cava tumor thrombus (IVCTT) remains a major clinical challenge. Venous outflow obstruction from the thrombus can precipitate severe lower-extremity edema and secondary deep vein thrombosis (DVT)...
Facilitators and Barriers to Cervical Cancer Screening Among Women in a Rural District of Northeastern Uganda, a Qualitative Study [0.03%]
Ibra Mutyaba,Hellen Akurut,Racheal Nabaasa et al.
Ibra Mutyaba et al.
Introduction: Cervical cancer screening in Uganda has remained relatively low, with fewer than one in 10 of eligible women screened, despite the availability of cervical cancer screening services in most health facilities...
Efficacy and Safety of Thermosensitive Hydrogel Combined with Pirarubicin via TACE for Hepatocellular Carcinoma: A Pilot Study [0.03%]
Chang Liu,Qihui Hu,Baoyong Zhou et al.
Chang Liu et al.
Aim: This pilot study aims to evaluate the technical feasibility, safety profile, and preliminary efficacy of Tepoxin, a thermosensitive hydrogel, combined with pirarubicin via transarterial chemoembolization (TACE) in pa...
Perioperative FLOT versus Definitive 50.4 Gy Chemoradiotherapy in Siewert II Esophagogastric Junction Adenocarcinoma: A Multicenter Retrospective Cohort Study [0.03%]
Sermin Dinc Sonusen,Zehra Sucuoglu Isleyen,Okan Aydin et al.
Sermin Dinc Sonusen et al.
Background: Optimal multimodal treatment for esophagogastric junction adenocarcinoma remains debated. While the ESOPEC trial supports perioperative FLOT, real-world evidence is limited, particularly for Siewert type II tu...
Oncolytic Vaccinia Virus-Engineered EVs Convert Tumor-Promoting Macrophages into Anti-Tumor Effectors [0.03%]
Liqiong Chen,Luyi Ye,Liuqian Bao et al.
Liqiong Chen et al.
Introduction: Extracellular vesicles (EVs) play a critical role in shaping the tumor immune microenvironment (TME) by mediating intercellular communication and transferring oncogenic proteins, microRNAs, and immunosuppres...
Digital Health in Pediatric Oncology and Hematooncology: A Quasi-Systematic Review of Telehealth, mHealth and Precision Medicine [0.03%]
Karolina Joanna Ziętara,Piotr Pawłowski,Natalia Zaj et al.
Karolina Joanna Ziętara et al.
Pediatric oncological and hematological diseases remain a significant challenge due to their complexity, the need for personalized treatment, and long-term follow-up. Recent advances in medical technologies, particularly in information tech...
Inflammatory and Nutritional Biomarkers Predict Response to Neoadjuvant Dual Anti-HER2 Therapy in HER2-Positive Breast Cancer: A Retrospective Cohort Study [0.03%]
炎症和营养生物标志物可预测赫尔辛基乳腺癌患者新辅助双重抗HER2治疗的疗效：回顾性队列研究
Hayriye Şahinli,Galip Can Uyar,Enes Yeşilbaş
Hayriye Şahinli
Purpose: Predicting response to neoadjuvant therapy (NAT) remains a clinical challenge in patients with HER2-positive breast cancer (BC). Systemic inflammatory and immune-nutritional biomarkers have emerged as potential p...
Regorafenib-Induced Stress Response Alters the Bioenergetic Profile of Osteosarcoma Cells and Modulates Gene Expression Associated with Metabolic regulation-a Potential Mechanism of Osteosarcoma Treatment-Related Adaptation [0.03%]
瑞戈非尼诱导的应激反应改变成骨细胞的能量代谢谱并调节与代谢调控相关的基因表达-可能是一种成骨细胞瘤治疗相关适应的潜在机制
Klaudia Marcinkowska,Anna Raciborska,Bożena Obmińska-Mrukowicz et al.
Klaudia Marcinkowska et al.
Purpose: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Despite advances in surgery and multiagent chemotherapy, outcomes remain poor for patients with metastatic or recurrent di...
The Evolving Role of Local Radiotherapy in the Management of Oligometastatic Non-Small Cell Lung Cancer [0.03%]
局灶放射治疗在寡转移非小细胞肺癌管理中的作用变迁
Xiaofei Zhang,Mengzhen Liu,Zhenbo Wang
Xiaofei Zhang
Oligometastasis represents an intermediate stage between locally advanced disease and widespread metastasis, typically referring to stage IV disease with a limited number of metastatic lesions (generally no more than five) and controlled pr...
Context-Dependent Dual Roles of the Plexin-B Family in Cancer Progression: Mechanisms and Therapeutic Implications [0.03%]
plexin-b家族在癌症进展中的上下文依赖性双重作用：机制和治疗意义
Xiuli Mao,Wenxian Lin,Xiamin Zhang et al.
Xiuli Mao et al.
The Plexin-B family, comprising Plexin-B1, Plexin-B2, and Plexin-B3, represents a class of single-pass transmembrane receptors whose context-dependent functional outputs are governed by six contextual determinants-ligand availability, co-re...