Aortic stiffness: pathophysiology, clinical implications, and approach to treatment [0.03%]
主动脉僵硬：病理生理、临床意义和治疗方法
Salil Sethi,Oscar Rivera,Rene Oliveros et al.
Salil Sethi et al.
Aortic stiffness is a hallmark of aging, and classic cardiovascular risk factors play a role in accelerating this process. Current changes in medicine, which focus on preventive care, have led to a growing interest in noninvasive evaluation...
Phases in development of an interactive mobile phone-based system to support self-management of hypertension [0.03%]
基于手机的互动系统辅助高血压自我管理的开发阶段研究
Inger Hallberg,Charles Taft,Agneta Ranerup et al.
Inger Hallberg et al.
Hypertension is a significant risk factor for heart disease and stroke worldwide. Effective treatment regimens exist; however, treatment adherence rates are poor (30%-50%). Improving self-management may be a way to increase adherence to tre...
Recruited renin-containing renal microvascular cells demonstrate the calcium paradox regulatory phenotype [0.03%]
新生肾入球微血管细胞的钙悖理调节表型研究
Spencer Macgriff,Richard E Woo,M Cecilia Ortiz-Capisano et al.
Spencer Macgriff et al.
Renin is the critical regulatory enzyme for production of angiotensin (Ang)-II, a potent vasoconstrictor involved in regulating blood pressure and in the pathogenesis of hypertension. Chronic sodium deprivation enhances renin secretion from...
No association between perfluoroalkyl chemicals and hypertension in children [0.03%]
全氟化化学品与儿童高血压无相关性
Sarah Dee Geiger,Jie Xiao,Anoop Shankar
Sarah Dee Geiger
Background: Hypertension is a leading cause of cardiovascular disease worldwide. Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are perfluoroalkyl chemicals (PFCs) used in the manufacture of common con...
Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure [0.03%]
AT2受体激活对血管生物学、肾功能和血压的影响
Leon A Danyel,Patrick Schmerler,Ludovit Paulis et al.
Leon A Danyel et al.
The angiotensin type 2 receptor (AT2R) and the receptor MAS are receptors within the renin-angiotensin system, which mediate tissue-protective actions such as anti-inflammation, antifibrosis, and antiapoptosis. In recent years, several prog...
Management of patients with resistant hypertension: current treatment options [0.03%]
抗高血压药物治疗抵抗患者的管理：目前的治疗方法
Nilay Kumar,David A Calhoun,Tanja Dudenbostel
Nilay Kumar
Resistant hypertension (RHTN) is an increasingly common clinical problem that is often heterogeneous in etiology, risk factors, and comorbidities. It is defined as uncontrolled blood pressure on optimal doses of three antihypertensive agent...
Mineralocorticoid receptor antagonists: emerging roles in cardiovascular medicine [0.03%]
盐皮质激素受体拮抗剂在心血管医学中的新角色
John W Funder
John W Funder
Spironolactone was first developed over 50 years ago as a potent mineralocorticoid receptor (MR) antagonist with undesirable side effects; it was followed a decade ago by eplerenone, which is less potent but much more MR-specific. From a ma...
Daniel Urban,Sebastian Ewen,Christian Ukena et al.
Daniel Urban et al.
Arterial hypertension is the most prevalent risk factor associated with increased cardiovascular morbidity and mortality. Although pharmacological treatment is generally well tolerated, 5%-20% of patients with hypertension are resistant to ...
Prevalence of hypertension and its risk factors in southwest Ethiopia: a hospital-based cross-sectional survey [0.03%]
埃塞俄比亚西南部高血压患病率及其危险因素的医院横断面调查
Esayas Kebede Gudina,Yadani Michael,Sahilu Assegid
Esayas Kebede Gudina
Background: Hypertension is a common medical condition worldwide. It is an important public health challenge because of the associated morbidity, mortality, and the cost to the society. The objective of this study was to ...
Current perspectives on treatment of hypertensive patients with chronic obstructive pulmonary disease [0.03%]
高血压合并慢性阻塞性肺疾病的治疗现状及展望
Dipak Chandy,Wilbert S Aronow,Maciej Banach
Dipak Chandy
Systemic hypertension and chronic obstructive pulmonary disease (COPD) frequently coexist in the same patient, especially in the elderly. Today, a wide variety of antihypertensive drugs with different mechanisms of action are available to t...