Dissecting the Causal Pathway from Herpes Zoster to Postherpetic Neuralgia: A Multi-Stage Mendelian Randomization Study Implicating VZV-Specific IgE and Cerebrospinal Fluid Metabolites [0.03%]
带状疱疹导致神经痛的因果链：一项多阶段孟德尔随机化研究，提示VZV特异性IgE和脑脊液代谢物的作用
Jianjin Zhang,Yanhong Chen,Xingyu Li et al.
Jianjin Zhang et al.
Background: Postherpetic neuralgia (PHN) develops in 10-20% of herpes zoster (HZ) patients, yet the causal mechanisms driving this transition from acute infection to chronic neuropathic pain remain elusive. VZV-specific i...
The Role of Central Sensitization in Responsiveness to Brain Stimulation for Patients with Nonspecific Chronic Low Back Pain - An Exploratory Study [0.03%]
中枢敏化在脑刺激治疗非特异性慢性下腰痛患者中的作用-一项探索性研究
Sharon Wang-Price,Jason Zafereo,Khalid Alkhathami et al.
Sharon Wang-Price et al.
Purpose: This exploratory study aimed to examine (1) the effects of a single session of repetitive transcranial magnetic stimulation (rTMS) on pain thresholds in patients with high vs. low central sensitization (CS) level...
Effects of Deep versus Moderate Neuromuscular Blockade on Postoperative Acute and Chronic Pain in Laparoscopic Gynecological Surgery [0.03%]
在妇科腹腔镜手术中深度神经肌肉阻滞与中度神经肌肉阻滞对术后急性疼痛和慢性疼痛的影响
Ying Zhao,Jingjing Zhang,Wei Qian et al.
Ying Zhao et al.
Purpose: To evaluate the effects of deep neuromuscular blockade (D-NMB) versus moderate NMB (M-NMB) on postoperative pain and chronic postsurgical pain (CPSP) in patients undergoing laparoscopic gynecological surgery. ...
Clinical Trial
Journal of pain research. 2026 May 1:19:592329. DOI:10.2147/JPR.S592329 2026
How Can the Sedative and Analgesic Effects of Virtual Reality Technology Be More Precisely Assessed in Pediatric Dental Care? Methodological Insights from an Ongoing Randomized Controlled Trial [Letter] [0.03%]
如何更精确地评估虚拟现实技术在儿科牙科护理中的镇静和止痛效果？一项正在进行的随机对照试验的方法学见解[信件]
Fei-Yi Zhao,Qiang-Qiang Fu,Jia-Yi Zhu
Fei-Yi Zhao
Retrograde Intrathecal Catheter Placement at L5/S1 for Sacropelvic Cancer Pain: A Pilot Feasibility Study [0.03%]
腰5骶1硬膜外导管逆行植入治疗骶 pelvis癌痛的可行性研究
James S Cho,Julia Zhu,Pritesh Topiwala et al.
James S Cho et al.
Background: Intrathecal drug delivery systems have a role in treating cancer pain. For patients with predominant sacropelvic pain, caudally directed retrograde catheter placement targeting L5/S1 represents an alternative ...
Dixon Up-and-Down Method for Optimizing Oxycodone Dosage in Painless Colonoscopy [0.03%]
度冷丁无痛结肠镜剂量优化的狄克逊试误法研究
Yujie Ding,Chunliu Hou,Yan Li
Yujie Ding
Aim: Inadequate analgesia during painless colonoscopy can result in undesirable body movements, undermining patient safety and procedural success. Oxycodone, known for its dual κ- and μ-receptor agonism, may provide eff...
Clinical Trial
Journal of pain research. 2026 Apr 30:19:591621. DOI:10.2147/JPR.S591621 2026
Factors Associated with Severe Primary Dysmenorrhea in Adolescent Girls: A Retrospective Single-Center Study [0.03%]
少女原发性痛经影响因素分析：单中心回顾性研究
Yao Hu,Yan Chen,Gaolian Li et al.
Yao Hu et al.
Objective: To identify the risk factors for severe primary dysmenorrhea in adolescent girls and provide evidence for clinical prevention and intervention. ...
Preoperative Beta and Gamma EEG Spectral Power as Independent Predictors of Acute Postoperative Pain in Spinal Surgery: A Prospective Observational Cohort Study [0.03%]
术前β和γ频段脑电图谱功率可独立预测脊柱手术后急性术后疼痛：一项前瞻性队列研究
Hui Wu,Meiyan Zhou,Songtao Liu et al.
Hui Wu et al.
Purpose: The purpose of this paper was to explore the relationship between preoperative EEG frequency band characteristics and postoperative acute pain in patients undergoing spinal surgery, in order to provide a scientif...
Anxiety as a Psychological Modulator of Endogenous Pain Inhibition in Chronic Neck Pain: Implications for Precision Rehabilitation [0.03%]
慢性颈部疼痛患者内源性痛觉抑制的焦虑介导模型及精准康复治疗意义研究
Carla S Enriquez,Alka Bishnoi,Musola N Oniyide et al.
Carla S Enriquez et al.
Objective: Chronic neck pain (CNP) is a highly prevalent musculoskeletal disorder with significant personal and socioeconomic impact. In conjunction with low back pain, CNP accounts for the highest healthcare expenditures...
Salivary Substance P Levels During Cesarean Section Under Spinal versus General Anesthesia: A Prospective Study [0.03%]
腰麻与全身麻醉下剖宫产术时唾液中P物质水平的比较研究
Ala A Alhowary,Omar Altal,Diab Bani Hani et al.
Ala A Alhowary et al.
Background: Substance P is a key neuropeptide involved in the transmission of nociceptive (pain) signals. The choice of anesthesia for childbirth, particularly for cesarean section (CS), is a critical decision that direct...