Systematic Analysis of E3 Ligase-Related Genes Identified UBE2L3 as a Prognostic Biomarker Associated With Drug Resistance in Acute Myeloid Leukemia [0.03%]
E3连接酶相关基因的系统分析鉴定出UBE2L3是急性髓系白血病预后生物标志物和药物抗性相关基因
Chun Ling,Nengneng Cao,Huiping Wang et al.
Chun Ling et al.
Background: Acute Myeloid Leukemia (AML) is a prevalent neoplastic disorder. The roles of E3 ubiquitin ligases and related genes in AML drug resistance and prognosis remain unclear. ...
A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy [0.03%]
TTN基因的新突变引起遗传性肥厚型心肌病的病例报道
Jiangtao Dong,Meilin Liu,Qianwen Chen et al.
Jiangtao Dong et al.
Background: Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy, with variable pathogenesis, clinical presentation, and prognosis. Although mutations in genes encoding sarcomere proteins have be...
Outcomes of Worsened Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Replacement [0.03%]
经导管主动脉瓣置换术后左室射血分数降低的结局
Ziyang Hu,Changjin Wang,Songyuan Luo et al.
Ziyang Hu et al.
Background: Left ventricular ejection fraction (LVEF) worsening after transcatheter aortic valve replacement (TAVR) was common in clinical practice. However, the effect of acute worsening LVEF is unclear. ...
Crotonylation-Related Prognostic Model of Esophageal Squamous Cell Carcinoma Based on Transcriptome Analysis and Single-Cell Sequencing Analysis [0.03%]
基于转录组分析和单细胞测序的食管鳞癌表观遗传修饰预后模型研究
Ruo-Yang Lin,Ren-Pin Chen,Fu-Qiang Lin
Ruo-Yang Lin
Background: Crotonylation is an emerging lysine acylation modification implicated in various diseases, yet its role in esophageal squamous cell cancer (ESCC) is unexplored. This study aimed to investigate the role of crot...
Factors Associated With Multi-Drug Resistant Organisms Among Bronchiectasis Patients: A Retrospective Study of Bronchiectasis Patients in Jordan [0.03%]
支气管扩张合并多重耐药菌的相关因素分析：约旦支扩患者的回顾性研究
Khaled Al Oweidat,Ahmad A Toubasi,Farah A Khraisat et al.
Khaled Al Oweidat et al.
Background: Bronchiectasis, a respiratory ailment, significantly impacts the life expectancy of individuals. This study aimed to explore the prevalence of multidrug-resistant organisms (MDROs) among bronchiectasis patient...
Impact of Initial Heart Rate, Diastolic Pressure, and Pulse Pressure on Prognostic Outcomes in Heart Failure Patients with Mildly Reduced Ejection Fraction [0.03%]
射血分数轻度降低的心力衰竭患者预后的影响因素：心率、舒张压及脉压的作用
Hailong Hu,Zhican Liu,Jianping Zeng et al.
Hailong Hu et al.
Background: Heart rate, diastolic pressure, and pulse pressure are key modifiable factors influencing heart failure prognosis. While heart failure with mildly reduced ejection fraction (HFmrEF) is a distinct subgroup of h...
AI-Assisted Compressed Sensing Enables Faster Brain MRI for the Elderly: Image Quality and Diagnostic Equivalence with Conventional Imaging [0.03%]
基于人工智能的压缩感知加速磁共振成像在老年人群中的应用：优于传统MRI的方法
Wenquan Gu,Chunhong Yang,Yuhui Wang et al.
Wenquan Gu et al.
Purpose: Conventional brain MRI protocols are time-consuming, which can lead to patient discomfort and inefficiency in clinical settings. This study aims to assess the feasibility of using artificial intelligence-assisted...
Risk Factors of Hemophagocytic Lymphohistiocytosis in Adults with Fever of Unknown Origin: A Retrospective Study [0.03%]
不明原因发热成人噬血细胞综合征的风险因素：一项回顾性研究
Fangbing Tian,Nana Xie,Wenjin Sun et al.
Fangbing Tian et al.
Purpose: Hemophagocytic lymphohistiocytosis (HLH) is a critical syndrome with a high mortality rate. In clinical practice, some patients with fever of unknown origin (FUO) can develop HLH, further complicating the diagnos...
Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy [0.03%]
急性突发性单侧前庭病变的损伤部位及其可能病因分析
Menglu Zhang,Jianrong Wang,Siru Xue et al.
Menglu Zhang et al.
Objective: Acute unilateral vestibulopathy (AUVP) is quite common in clinical practice, but lesion localization and etiological diagnosis of AUVP remain the current clinical challenges, and have always been the focus for ...
Diagnostic Value of Measurements of Median Nerve Diameter at the Site of the Maximal Stenosis in Carpal Tunnel Syndrome [0.03%]
测定腕管综合征正中神经最狭窄部位直径的诊断价值
Agnieszka Fryźlewicz,Gabriela Rusin,Wojciech Rudnicki et al.
Agnieszka Fryźlewicz et al.
Introduction: Ultrasonography is increasingly used to diagnose the carpal tunnel syndrome (CTS). Most frequently, the enlargement of the nerve cross-sectional area (CSA) at the tunnel inlet serves to confirm the diagnosis...