Hypervirulent and Drug-Resistant Klebsiella pneumoniae: Clinical Challenges and Alternative Treatment Strategies [0.03%]
高毒力和耐药肺炎克雷伯菌：临床挑战与替代治疗策略
Sulaiman Bani Abdel-Rahman,Hala Altarawneh,Hassan Ahmad Hasan Alfreahat et al.
Sulaiman Bani Abdel-Rahman et al.
Klebsiella pneumoniae is a major opportunistic pathogen responsible for a wide range of hospital- and community-acquired infections, including respiratory tract infections, urinary tract infections, meningitis, and liver abscesses. Among it...
Precision Thyroid Oncology: A Review of Multi-Omics Biomarkers and Spatiotemporal Technologies [0.03%]
精准甲状腺肿瘤学：多组学生物标志物与时空技术综述
Lei Huang,Xinghua Deng,Zhenjun Xi et al.
Lei Huang et al.
Thyroid cancer (TC), the most prevalent endocrine malignancy worldwide, encompasses a broad spectrum of biological behaviors ranging from indolent microcarcinomas to lethal anaplastic variants. Despite advancements in standard care, critica...
Imaging Biomarkers of Cognitive Impairment in Sarcopenia: A Narrative Review [0.03%]
肌少症认知障碍的影像生物标志物：综述性研究
Wen-Xuan Lei,Jing-Jun Zhu,Yan-Ting Jiang et al.
Wen-Xuan Lei et al.
Sarcopenia is characterized by progressive declines in muscle strength, mass, and physical function. Mild cognitive impairment (MCI), also referred to as mild neurocognitive disorder (mNCD), involves a measurable reduction in cognitive abil...
Prevalence and Sex-Specific Distribution of Electrocardiographic Variants in Normotensive Nigerian University Students: A Cross-Sectional Study [0.03%]
尼日利亚大学生正常血压者心电图变异的患病率及性别分布：一项横断面研究
Jovita E Egharevba,James Nelson Okema,Clinton Uche Nwanaga et al.
Jovita E Egharevba et al.
Background: Electrocardiographic (ECG) variants occurring in the absence of known cardiac disease are common in healthy young adults but remain poorly characterized in sub-Saharan African populations. Contemporary ECG ref...
BCG Vaccination Modulates Long-Term TNF-α and sCD40L in COVID-19: An Exploratory Longitudinal Study [0.03%]
卡介苗会调节COVID-19患者的长期TNF-α和sCD40L：一项探索性纵向研究
Caroline Fávero,Gabriela Barbosa,Vanessa Pellegrini et al.
Caroline Fávero et al.
Background: Bacillus Calmette-Guérin (BCG) vaccination exerts non-specific immunomodulatory effects through trained immunity, potentially modulating inflammatory responses in COVID-19. Tumor necrosis factor-alpha (TNF-α...
Multigene Screening of B-Vitamin Metabolism Pathways in Hypertensive Disorders of Pregnancy: Toward Precision Prenatal Care [0.03%]
高血压疾病的维生素B代谢通路的多基因筛查：朝向精确产前护理
Tingyin Zhang
Tingyin Zhang
Hypertensive disorders of pregnancy (HDP) are among the most common and serious complications of pregnancy, exerting substantial effects on both maternal and fetal health. B vitamins particularly folate, vitamin B6, and vitamin B12 are esse...
Identification of Key Genes and Exploration of Therapeutic Targets for Chronic Tendon Injury Based on Bioinformatics and Machine Learning [0.03%]
基于生物信息学和机器学习的慢性肌腱损伤关键基因鉴定及治疗靶点探索
Zishen Cheng,Weina Ren,Yuqing Wang et al.
Zishen Cheng et al.
Background: Chronic tendon injury (CTI) is a common musculoskeletal disorder with complex molecular mechanisms, and currently lacks effective targeted therapeutic strategies. A comprehensive analysis of its key pathogenic...
Prevalence of Cardiometabolic Abnormalities Among Male Licensed Pilots and Community Health Examination Participants in China: A Cross-Sectional Comparison [0.03%]
中国男性飞行员和社区健康检查人员心血管代谢异常的流行率对比：横断面研究
Xinxin Fan,Yiqing Shen,Qiuwan Wei et al.
Xinxin Fan et al.
Background: Metabolic abnormalities are common in adult populations, but comparative data between licensed pilots and community health examination participants in China remain limited. This study descriptively compared ca...
A Retrospective Study of Preventive Anticoagulant Therapy Among Trauma Patients in Yichang Area Through Clinical Data Review and Clinician Survey [0.03%]
基于临床数据与专家调研的宜昌地区创伤患者预防性抗凝治疗回顾性研究
Siqi Chen,Miao Zou,Man Chen et al.
Siqi Chen et al.
Background: Trauma-induced coagulopathy is one of the important causes for deaths after trauma. This study aimed to explore the current state of preventive anticoagulation therapy and the clinical factors affecting the ap...
The Mechanosensation-Metabolism-Inflammation Axis: The Central Role of Piezo1 and TRPV4 in Hypertension-Related Atherosclerosis [0.03%]
机械感受-代谢-炎症轴在高血压相关动脉粥样硬化中的作用：Piezo1和TRPV4的中心作用
Ying-Ying Mu,Ting-Ting Liu,Jie-Lei Xu et al.
Ying-Ying Mu et al.
Atherosclerosis is a core independent risk factor for cardiovascular events. The abnormal hemodynamic microenvironment mediated by hypertension is a key initiating factor for its development and progression, and mechanosensitive ion channel...