AI-ECG for Echocardiography Triage in Structural Heart Disease: Evidence, Implementation, and Future Directions [0.03%]
人工智能心电图在结构性心脏病超声心动图分诊中的应用：证据、实施和未来方向
Qianwen Tang,Kunfei Deng,Yu Cui et al.
Qianwen Tang et al.
Structural heart disease (SHD), including left ventricular systolic dysfunction, valvular heart disease, hypertrophic cardiomyopathy, cardiac amyloidosis, and pulmonary hypertension, remains underdiagnosed despite the increasing availabilit...
Factors Associated with Malignant Gastric Ulcers: A 10-year Retrospective Cohort Study [0.03%]
恶性胃溃疡的危险因素：一项十年回顾队列研究
Anas Zayad,Yousef Yahia,Prem Chandra et al.
Anas Zayad et al.
Background: Gastric ulcers carry a recognized risk of underlying malignancy. Regional evidence remains limited in the Middle East, where historically high Helicobacter pylori prevalence contrasts with comparatively low ga...
An Evidence Atlas of Diagnostic Tests for Genitourinary Tuberculosis: A Laboratory-Centered Framework [0.03%]
泌尿生殖器结核诊断试验证据图谱：以实验室为中心的框架
Hailing Zeng,Qiongfang Zhang
Hailing Zeng
Background: Genitourinary tuberculosis (GUTB) remains difficult to diagnose because of nonspecific clinical manifestations, low bacterial burden, and variability in diagnostic performance across laboratory methods and spe...
Serum Untargeted Metabolomics Profiling of Esophageal Squamous Cell Carcinoma in High-Incidence Areas of China [0.03%]
中国高发地区食管鳞癌血清非靶向代谢组学特征分析
Yonghao Li,Lu Zhou,Ruixue Huang et al.
Yonghao Li et al.
Background: As a frequent malignant tumor arising in the upper gastrointestinal tract, esophageal squamous cell carcinoma (ESCC) exhibits an exceptionally high prevalence in China. Metabolic reprogramming is a hallmark of...
Unaddressed Biases in a Retrospective Study of Anticoagulant Prophylaxis in Trauma Patients [Letter] [0.03%]
创伤患者抗凝预防的回顾性研究中的偏差[来信]
Cheng-Wei Lu,Kuo-Chen Chang
Cheng-Wei Lu
Synergistic Effects of Thymoquinone, 3-Hydrazinoquinoxaline-2-Thiol, and Amphotericin B Against Methicillin-Resistant Staphylococcus aureus: In vitro and in silico Evaluation [0.03%]
百里醌，3-肼基喹喔啉-2-巯和两性霉素B对抗耐甲氧西林金黄色葡萄球菌的协同效应：体外和分子对接研究
Karem Ibrahem,Abdelbagi Alfadil
Karem Ibrahem
Introduction: Bacterial infections continue to pose a major global health challenge, intensified by the increasing prevalence of antimicrobial-resistant pathogens such as Methicillin-resistant Staphylococcus aureus (MRSA)...
Integrated Transcriptomics and Experimental Validation Reveal Müller Cell-Driven PANoptosis in Diabetic Retinopathy via PSAP-GPR37 Signaling [0.03%]
整合转录组学和实验验证揭示了糖尿病性视网膜病变中通过PSAP-GPR37信号的Müller细胞驱动的PANoptosis
Jing Li,Yicong Chen,Yunxiang Chao et al.
Jing Li et al.
Background: Diabetic retinopathy (DR) is a major complication of diabetes leading to severe visual impairment. PANoptosis, a pro-inflammatory programmed cell death (PCD), has emerged as a potential pathological mechanism....
Kena Zhou,Leheng Liu,Jingpiao Bao et al.
Kena Zhou et al.
Purpose: Acute pancreatitis is a common disease with limited supportive treatments. Finding effective biomarkers is of great significance for early diagnosis and therapy, as well as to achieve better prognosis. ...
Andrographolide in Sepsis: Mechanistic Basis, New Drug States, and Advanced Delivery Systems [0.03%]
andrographolide在防治脓毒症中的机制、新药剂和先进递送系统
Qi Zhu,Dandan Hu,Jian Xing et al.
Qi Zhu et al.
Sepsis is a leading cause of preventable mortality, and effective adjunct therapies that recalibrate the host response remain scarce. Andrographolide, a diterpenoid lactone from Andrographis paniculata, shows anti-inflammatory, antioxidant,...
Targeting Ferroptosis for Cerebral Neuroprotection in Ischemic Stroke: Pathophysiological Insights [0.03%]
靶向铁死亡在缺血性脑卒中神经保护中的作用：病理生理学见解
Chong Song,Songlin Tang,Yongpan Huang et al.
Chong Song et al.
Acute ischemic stroke, a leading cause of neurological disability, stemed from cerebral hypoperfusion-induced ischemia/reperfusion (I/R) injury. Ferroptosis, an iron-dependent, lipid peroxidation-driven cell death, has emerged as a key path...