Population Pharmacokinetics-Based Evaluation of Ceftazidime-Avibactam Dosing Regimens in Critically and Non-Critically Ill Patients With Carbapenem-Resistant Klebsiella pneumoniae [0.03%]
基于人群药代动力学的重症与非重症碳青霉烯类耐药克雷伯菌感染患者头孢他啶-阿维巴坦给药方案评估
Yiying Chen,Bo Chen,Yingbin Huang et al.
Yiying Chen et al.
Purpose: This study aimed to describe the population pharmacokinetics (PopPK) of ceftazidime-avibactam (CAZ-AVI) in adult patients, and to develop optimal dosing regimens for both non-critically ill and critically ill pat...
Emerging Mobile Colistin Resistance Gene Mcr-1 and Mcr-10 in Enterobacteriaceae Isolates From Urban Sewage in China [0.03%]
中国城市污水中肠杆菌目分离株中出现的新型移动性多粘菌素抗性基因Mcr-1和Mcr-10
Yujing Zhang,Jiajie Chen,Xinyu Yang et al.
Yujing Zhang et al.
Purpose: This study aimed to investigate the epidemiology and dissemination of mcr-positive Enterobacteriaceae in urban sewage in Yangzhou, China. Methods...
Clinical Characteristics and Treatment Outcomes of Pediatric Drug-Resistant Mycoplasma pneumoniae Pneumonia in the Post-COVID-19 Era [0.03%]
COVID-19大流行后儿童耐药肺炎支原体肺炎的临床特征和治疗转归
Qin Sun,Jindou Hao,Qixin Zhou et al.
Qin Sun et al.
Background: Mycoplasma pneumoniae pneumonia (MPP) is a prevalent disease among children. Typically, macrolides are the first-line treatment for MPP in China. However, the number of cases resistant to macrolides has been r...
Polymyxin B in The Treatment of Infections Caused by Multidrug-Resistant Gram-Negative Bacteria in Children: A Retrospective Case Series and A Literature Review [0.03%]
多黏菌素B用于治疗儿童多重耐药革兰氏阴性菌感染的疗效：一项病例系列分析及文献回顾
Aihua Yan,Xiangcheng Pan,Siyu Li et al.
Aihua Yan et al.
Background: Multidrug-resistant Gram-negative bacteria (MRGN) pose a significant threat and require priority attention. Polymyxin B (PMB) retains substantial activity against MRGN and makes it potentially the last resort ...
Predictors for Invasive Pulmonary Aspergillosis in Acute-on-Chronic Liver Failure Patients: A Retrospective Study [0.03%]
急性加重的慢性肝功能衰竭患者侵袭性肺部曲霉菌病的预测因素：一项回顾性研究
Chenxi Yuan,Rongqing Zhu,Lifen Hu et al.
Chenxi Yuan et al.
Introduction: Acute-on-chronic liver failure (ACLF) is a severe syndrome that manifests as acute liver function deterioration and organ failure. Coinfection with invasive pulmonary aspergillosis (IPA) in ACLF patients is ...
Staphylococcal Drug Resistance: Mechanisms, Therapies, and Nanoparticle Interventions [0.03%]
金黄色葡萄球菌的耐药性：机制、疗法和纳米颗粒干预措施
Kunyu Shao,Yuxun Yang,Xuankai Gong et al.
Kunyu Shao et al.
The increasing incidence of antibiotic resistance in Staphylococcus aureus (S. aureus) poses a substantial threat to global public health. In recent decades, the evolution of bacteria and the misuse of antibiotics have led to a progressive ...
Risk Factors for Development and Mortality of Carbapenem-Resistant Pseudomonas aeruginosa Bloodstream Infection in a Chinese Teaching Hospital: A Seven-Year Retrospective Study [0.03%]
中国教学医院鲍曼不动杆菌血液感染的发生及死亡的危险因素 ：一项七年回顾性研究
Luyan Dong,Yingbin Huang,Shengcen Zhang et al.
Luyan Dong et al.
Objective: Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative opportunistic pathogen, which can cause acute and chronic infections, often resulting in high mortality. The aim of this study was to investigate the ri...
Diagnostic Utility of Pleural C-Reactive Protein and Procalcitonin for Parapneumonic Pleural Effusion: A Head-to-Head Comparison Study [0.03%]
胸腔C反应蛋白和降钙素原对肺炎旁胸腔积液诊断作用的直接比较研究
Qian Yang,Su-Na Cha,Yan Niu et al.
Qian Yang et al.
Introduction: The diagnostic utility of pleural fluid C-reactive protein (CRP) and procalcitonin (PCT) for parapneumonic pleural effusion (PPE) is a subject of ongoing investigation. There remains lack studies comparing t...
Dynamic Serotype Distribution and Antimicrobial Resistance of Salmonella Isolates from 2019 to 2023 in Guizhou, China [0.03%]
2019年至2023年在中国贵州省沙门氏菌分离株的动态血清型分布和抗菌药物耐药性分析
Jingtong Wu,Lv You,Yanmin Liu et al.
Jingtong Wu et al.
Introduction: Salmonella, a leading cause of human infectious diarrhea diseases, foodborne illness, and zoonotic infections, poses a significant health burden. ...
Identification of Pathogens in HIV-Infected Patients Using Metagenomic Next-Generation Sequencing (mNGS) as Compared to Conventional Microbiological Tests (CMTs) [0.03%]
使用宏基因组下一代测序(mNGS)与常规微生物检测(CMTs)鉴定HIV感染患者的病原体
Xiaohong Zhu,Li Cao,Juan Wang et al.
Xiaohong Zhu et al.
Background: The rapid and accurate identification of infectious pathogens in HIV-infected patients remains a challenge. Metagenomic next-generation sequencing (mNGS) is a panpathogen assay for rapid diagnosis of infectiou...