Lactate Dehydrogenase to Albumin Ratio as a Predictor of Severe Community-Acquired Pneumonia in Patients Aged 60 years and Above: A Retrospective Cohort Study [0.03%]
乳酸脱氢酶与白蛋白比值可作为老年社区获得性肺炎严重不良结局的预测因素：回顾性队列研究
Congfeng Li,Mengyu Lian,Lin Ding et al.
Congfeng Li et al.
Purpose: Although albumin-based indices have prognostic value in older adults with community-acquired pneumonia (CAP), the predictive role of lactate dehydrogenase to albumin ratio (LAR) remains insufficiently explored. T...
Efficacy and Safety of Omadacycline in Patients with Mycoplasma Pneumoniae Harboring the 23S rRNA A2063G Mutation [0.03%]
奥马环素对耐药肺炎支原体（23S rRNA A2063G基因突变）感染患者的疗效和安全性
Min Chen,Wei An,Shasha Fang et al.
Min Chen et al.
Objective: Mycoplasma pneumoniae is a major pathogen of community-acquired bacterial pneumonia (CABP). Macrolide-resistant Mycoplasma pneumoniae (MRMP) harboring the 23S rRNA A2063G mutation poses a global therapeutic cha...
Diosgenin Promotes Bacterial Clearance in Bladder Epithelial Cells by Regulating Rab27b Expression: A Study Based on Virtual Screening and Experimental Validation [0.03%]
薯蓣皂苷通过调节Rab27b表达促进膀胱上皮细胞细菌清除作用：基于虚拟筛选和实验验证的研究
Hao Yin,Jiamin Yin,Jiahao Zhang et al.
Hao Yin et al.
Introduction: The annual rise in antimicrobial resistance (AMR) rates highlights the critical significance of exploring non-antibiotic therapies for infectious diseases. Urinary tract infection (UTI) is one of the most co...
Real-World Experience with High- versus Low-Dose Polymyxin B for Pulmonary Infections: A Retrospective Cohort Study [0.03%]
高剂量多粘菌素B治疗肺部感染的临床疗效及安全性：回顾性队列研究
Lin Li,Hongyu Che,Xing Guo et al.
Lin Li et al.
Background: Polymyxin B(PMB) is crucial for treating carbapenem-resistant Gram-negative pulmonary infections. Despite existing guidelines, real-world dosing varies widely. The clinical and economic outcomes associated wit...
Disseminated Mycobacterium avium Complex Infection in an HIV Patient with a History of Talaromyces marneffei: Diagnostic Value of Blind Subculture and Suspected Management Challenges of Immune Reconstitution Inflammatory Syndrome [0.03%]
一位有马尔尼菲蓝状菌病史的HIV患者出现鸟分枝杆菌复合体播散感染：盲传代培养的诊断价值及免疫重建炎性综合征疑似病例处理难题
Xiaoqin Niu,Qinlong Yu,Jiong Gu et al.
Xiaoqin Niu et al.
This study reported a 33-year-old male acquired immune deficiency syndrome (AIDS) patient with a 10-year human immunodeficiency virus (HIV) infection history, poor antiretroviral therapy (ART) adherence, and two previous Talaromyces marneff...
Antimicrobial Peptides Against Antimicrobial-Resistant Bacteria: Focus on Machine Learning [0.03%]
利用机器学习对抗抗菌素耐药细菌的抗生素肽研究
Hamed Tahmasebi,Mohammad Reza Arabestani
Hamed Tahmasebi
Antimicrobial resistance (AMR) represents a pressing public health threat of the 21st century, with an estimated ten million deaths annually from drug-resistant infections by 2050. Diminishing pipelines and the accelerating emergence of mul...
Penicillin Allergy Labels, Broad-Spectrum Antibiotic Use, and Chronic Obstructive Pulmonary Disease Exacerbations: A Population-Based Cohort Study from China [0.03%]
青霉素过敏标签、广谱抗生素使用与慢性阻塞性肺疾病急性加重：一项来自中国的队列研究
Peng Wu,Tian Xie,Haonan Pan et al.
Peng Wu et al.
Background: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, and acute exacerbations drive most of its burden. Around half of exacerbations are infection related, and penicillin-...
Epidemiology, Antifungal Susceptibility, and in-Hospital Mortality of Candidemia in a Tertiary Hospital of China: A 10-Year Retrospective Analysis [0.03%]
中国一家三级医院10年回顾性分析的 candida血流感染的流行病学、抗真菌敏感性和院内死亡率
Min Gu,Chunliang Zhu,Wenying Xia et al.
Min Gu et al.
Purpose: In response to the increasing incidence of candidemia, this study aimed to investigate its epidemiology and risk factors for in-hospital mortality in an eastern Chinese tertiary hospital, thereby guiding clinical...
A Novel Model for Predicting Post-Craniotomy Meningitis Using Early Postoperative Risk Stratification: A Multi-Center Retrospective Study [0.03%]
基于早期术后危险分层的颅骨手术后脑膜炎预测模型的多中心回顾性研究
Jingwei Zhao,Xiyu Chen,Lei Wu et al.
Jingwei Zhao et al.
Purpose: Early prediction of post-craniotomy meningitis (PCM) is critical for optimizing prognosis. Given the limitations of existing prediction tools, this study sought to develop and externally validate a novel model fo...
Purulent Pericarditis Caused by Polymicrobial Periodontal Pathogens (Tannerella forsythia, Fusobacterium nucleatum, and Porphyromonas gingivalis): A Case Report and Literature Review [0.03%]
由牙周病致病菌（福赛斯坦纳菌、核梭杆菌和齿龈卟啉单胞菌）引起的化脓性心包炎：一例病例报告及文献回顾
Bao-Hua Wei,Hong-Ju Da
Bao-Hua Wei
Background: Purulent pericarditis is a rare, life-threatening infection, most commonly caused by bacteria such as Staphylococcus aureus. We report an exceptional case of hematogenously disseminated infection probably orig...