Metagenomic Next-Generation Sequencing for Brain Abscess: Improved Pathogen Detection, Targeted Antimicrobial Therapy, and Association with Fewer Surgical Interventions [0.03%]
脑脓肿元基因组下一代测序：改善病原检测、目标抗菌治疗和较少的外科手术干预
Xiangyun Li,Meixiang Fan,Jiang Yue et al.
Xiangyun Li et al.
Background: Brain abscesses demand prompt, accurate pathogen identification; however, identification using conventional culture is limited, especially for anaerobic and polymicrobial infections. We compared the diagnostic...
Clinical and Epidemiologic Characteristics of Anaerobic Bacteria Originating from Blood Cultures: A Five-Year Retrospective Study [0.03%]
源于血培养的厌氧菌的临床和流行病学特征：一项五年的回顾性研究
Yaqin Peng,Jiamin Qin,Lu Bai et al.
Yaqin Peng et al.
Background: With the rise of anaerobic bacteremia and resistance to anaerobes for commonly used agents, the resistance patterns of many anaerobes have changed significantly among different geographic areas and medical fac...
Effect of Remdesivir on Mortality in Mechanically Ventilated COVID-19 Patients: A Target Trial Emulation Using Inverse Probability of Treatment Weighting [0.03%]
利巴韦林对重症监护新冠患者的疗效：使用逆概率加权的靶标试验模拟研究
Yan-Ru Wang,Hong-Jie Jhou,Po-Huang Chen et al.
Yan-Ru Wang et al.
Background: The efficacy of remdesivir in critically ill COVID-19 patients requiring mechanical ventilation remains controversial. Although current guidelines recommend against routine use in this population, clinical pra...
Culture-Confirmed Severe Methicillin-Susceptible Staphylococcus aureus Pneumonia with Lung Abscess, Bacteremia, and Hydropneumothorax Managed without ECMO: A Case Report [0.03%]
经文化确认的甲氧西林敏感金黄色葡萄球菌严重肺炎、肺脓肿、菌血症和液气胸病例报告（无需ECMO治疗）
Xuqin Li,Yue Zhu,Fangfang Huang et al.
Xuqin Li et al.
Background: Methicillin-susceptible Staphylococcus aureus (MSSA) can cause rapidly destructive pneumonia complicated by lung abscess, bacteremia, empyema, and hydropneumothorax. Extracorporeal membrane oxygenation (ECMO) ...
The Analysis of Risk Factors of Stroke-Associated Pneumonia in Patients with Acute Stroke Based on Lasso Regression and the Construction of a Nomogram Prediction Model [0.03%]
基于Lasso回归的急性卒中患者卒中相关性肺炎危险因素分析及列线图预测模型的构建
Gaoyi Wu,Xiwen Zhong,Daicheng Lin
Gaoyi Wu
Objective: To identify the risk factors for stroke-associated pneumonia (SAP) in patients with acute cerebrovascular stroke (ACS) using LASSO regression analysis and to construct a nomogram-based prediction model. ...
Antimicrobial Resistance in Somalia: A Growing Public Health Crisis in a Fragile Health System-A Narrative Review of Challenges, Healthcare Gaps, and Policy Recommendations [0.03%]
索马里抗菌药物耐药性问题：脆弱卫生系统中的日益严重的公共卫生危机——挑战、医疗缺口及政策建议的叙述性回顾
Widad Mohamed Hassan
Widad Mohamed Hassan
Background: Antimicrobial resistance (AMR) has emerged as one of the most serious global public health threats and represents a growing concern in fragile and conflict-affected countries such as Somalia. The increasing em...
A Short-Course Regimen Containing Delamanid, Bedaquiline and Linezolid for the Treatment of Drug-Resistant Tuberculosis: A Retrospective Study from China [0.03%]
含德拉马尼、贝达喹啉和利奈唑胺短程化疗治疗耐药结核病的疗效：一项中国回顾性研究
Long Jin,Xiaolei Zhang,Huailong Jiang et al.
Long Jin et al.
Purpose: To assess the efficacy and safety of delamani (Dlm), bedaquiline (Bdq) and linezolid (Lzd) in multidrug-resistant tuberculosis (MDR-TB) and rifampicin-resistant tuberculosis (RR-TB). ...
Adult Empyema Caused by Refractory Methicillin-Resistant Staphylococcus aureus Treated Using Linezolid as Salvage Therapeutic Option: A Report of Two Cases [0.03%]
利奈唑胺治疗难治性甲氧西林耐药金黄色葡萄球菌成人脓胸2例报告
Masafumi Seki,Takuya Nagai,Konosuke Ozawa
Masafumi Seki
Background: The pathogenesis and treatment of pulmonary lesions caused by methicillin-resistant Staphylococcus aureus (MRSA) infection have been unclear because MRSA has usually been considered a colonizer. ...
Clinical Value of Contrast-Enhanced Ultrasound and Ultrasound Elastography in the Pathological Classification and Treatment Response Prediction of Cervical Tuberculous Lymphadenitis [0.03%]
造影超声和弹性成像鉴别诊断颈淋巴结结核的价值及预判抗痨疗效的临床价值研究
Xiangjun Fu,Xianzhong Zhu,Xiaoyan Liu
Xiangjun Fu
Objective: Limited evidence exists on imaging-based classification and treatment response prediction in cervical tuberculous lymphadenitis (CTL). This study aimed to investigate the clinical value of contrast-enhanced ult...
Species Distribution, Antifungal Resistance, and Risk Factors of Candida Bloodstream Infections in a Tertiary Care Hospital in Iran: A Two-Year Cross-Sectional Study [0.03%]
伊朗三级医疗保健机构念珠菌败血症的物种分布、抗真菌耐药性及危险因素：为期两年的横断面研究
Hadis Jafarian,Fatemeh Ghasemi,Parisa Badiee
Hadis Jafarian
Background: Understanding trends in Candida infections and their resistance patterns is essential for improving patient outcomes and guiding effective treatment strategies. This study aimed to investigate the distribution...