Stem cell technology for bone regeneration: current status and potential applications [0.03%]
骨再生的干细胞技术：现状与潜在应用
Greg Asatrian,Dalton Pham,Winters R Hardy et al.
Greg Asatrian et al.
Continued improvements in the understanding and application of mesenchymal stem cells (MSC) have revolutionized tissue engineering. This is particularly true within the field of skeletal regenerative medicine. However, much remains unknown ...
Hedgehog signaling in cancer stem cells: a focus on hematological cancers [0.03%]
刺猬信号在癌症干细胞中的作用：集中讨论血液系统恶性肿瘤中的应用和展望
Victoria Campbell,Mhairi Copland
Victoria Campbell
The stem cell paradigm was first demonstrated in hematopoietic stem cells. Whilst classically it was cytokines and chemokines which were believed to control stem cell fate, more recently it has become apparent that the stem cell niche and h...
Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells [0.03%]
Y-27632无法改善成人人类脂肪来源干细胞的培养效果
Nuno Jorge Lamas,Sofia C Serra,António J Salgado et al.
Nuno Jorge Lamas et al.
Y-27632 is a well-known inhibitor of the Rho-associated coiled kinase (ROCK) and has been shown to significantly improve the culture of a variety of multipotent stem cell types. However, the effects of Y-27632 on the expansion of adult huma...
Fetal exposure to a diabetic intrauterine environment resulted in a failure of cord blood endothelial progenitor cell adaptation against chronic hypoxia [0.03%]
糖尿病宫内环境暴露致胎盘脐血内皮前体细胞对慢性缺氧的适应性降低
U Deniz Dincer
U Deniz Dincer
Gestational diabetes mellitus (GDM) has long-term health consequences, and fetal exposure to a diabetic intrauterine environment increases cardiovascular risk for her adult offspring. Some part of this could be related to their endothelial ...
Some aspects of allogeneic stem cell transplantation in patients with myelodysplastic syndrome: advances and controversy [0.03%]
异基因干细胞移植治疗骨髓增生异常综合征的进展与争议
Olga Blau,Igor Wolfgang Blau
Olga Blau
Myelodysplastic syndrome (MDS) is a heterogeneous group of myeloid disorders. MDS remains a disease of elderly patients; moreover, the incidence of high risk MDS is proportionally greater in elderly patients, with increased frequency of sec...
From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells [0.03%]
从牙髓再生医学到再生医学：口腔干细胞的进步、挑战及潜在应用
Li Xiao,Masanori Nasu
Li Xiao
Adult mesenchymal stem cells (MSCs) and epithelial stem cells play essential roles in tissue repair and self-healing. Oral MSCs and epithelial stem cells can be isolated from adult human oral tissues, for example, teeth, periodontal ligamen...
Drew E Glaser,Andrew B Burns,Rachel Hatano et al.
Drew E Glaser et al.
Vascular progenitor cells are desirable in a variety of therapeutic strategies; however, the lineage commitment of endothelial and smooth muscle cell from a common progenitor is not well-understood. Here, we report the generation of the fir...
Cat amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation [0.03%]
猫胎盘多功能细胞进行细胞移植是安全的且不具备致瘤性
Atanasio S Vidane,Aline F Souza,Rafael V Sampaio et al.
Atanasio S Vidane et al.
Amnion-derived mesenchymal stem cells (AMSCs) are multipotent cells with an enhanced ability to differentiate into multiple lineages. AMSCs can be acquired through noninvasive methods, and therefore are exempt from the typical ethical issue...
Stem cell treatment for avascular necrosis of the femoral head: current perspectives [0.03%]
股骨头缺血性坏死的干细胞治疗：目前的展望
Matthew T Houdek,Cody C Wyles,John R Martin et al.
Matthew T Houdek et al.
Avascular necrosis (AVN) of the femoral head is a progressive disease that predominantly affects younger patients. Although the exact pathophysiology of AVN has yet to be elucidated, the disease is characterized by a vascular insult to the ...
Amniotic membrane-derived stem cells: immunomodulatory properties and potential clinical application [0.03%]
蜕膜干细胞：免疫调节特性及潜在临床应用
Carmen L Insausti,Miguel Blanquer,Ana M García-Hernández et al.
Carmen L Insausti et al.
Epithelial and mesenchymal cells isolated from the amniotic membrane (AM) possess stem cell characteristics, differentiation potential toward lineages of different germ layers, and immunomodulatory properties. While their expansion and diff...