Human adipose stem cell and ASC-derived cardiac progenitor cellular therapy improves outcomes in a murine model of myocardial infarction [0.03%]
人源脂肪间充质干细胞及其分化的心脏祖细胞在小鼠心肌梗死模型中的治疗效应研究
Philip Mc Davy,Kevin D Lye,Juanita Mathews et al.
Philip Mc Davy et al.
Background: Adipose tissue is an abundant and potent source of adult stem cells for transplant therapy. In this study, we present our findings on the potential application of adipose-derived stem cells (ASCs) as well as i...
Vaughan Feisst,Sarah Meidinger,Michelle B Locke
Vaughan Feisst
Since the discovery of adipose-derived stem cells (ASC) in human adipose tissue nearly 15 years ago, significant advances have been made in progressing this promising cell therapy tool from the laboratory bench to bedside usage. Standardiza...
Mesenchymal and induced pluripotent stem cells: general insights and clinical perspectives [0.03%]
间充质干细胞及诱导多潜能干细胞：总体认识及临床应用前景
Helena D Zomer,Atanásio S Vidane,Natalia N Gonçalves et al.
Helena D Zomer et al.
Mesenchymal stem cells have awakened a great deal of interest in regenerative medicine due to their plasticity, and immunomodulatory and anti-inflammatory properties. They are high-yield and can be acquired through noninvasive methods from ...
Cody C Wyles,Matthew T Houdek,Atta Behfar et al.
Cody C Wyles et al.
Osteoarthritis (OA) is a painful chronic condition with a significant impact on quality of life. The societal burden imposed by OA is increasing in parallel with the aging population; however, no therapies have demonstrated efficacy in prev...
Progress toward curing HIV infection with hematopoietic cell transplantation [0.03%]
造血干细胞移植治疗艾滋病的进展
Lawrence D Petz,John C Burnett,Haitang Li et al.
Lawrence D Petz et al.
HIV-1 infection afflicts more than 35 million people worldwide, according to 2014 estimates from the World Health Organization. For those individuals who have access to antiretroviral therapy, these drugs can effectively suppress, but not c...
Islam M Saadeldin,Hyun Ju Oh,Byeong Chun Lee
Islam M Saadeldin
A myriad of locally produced factors into the microenvironment of the reproductive tract is regulated, not one-way but rather, through embryonic-maternal cross-talk. In this mini-review, we focused on the exosomes, which are cell-derived ve...
Mohammad T Alrefai,Divya Murali,Arghya Paul et al.
Mohammad T Alrefai et al.
Stem cell therapy and tissue engineering represent a forefront of current research in the treatment of heart disease. With these technologies, advancements are being made into therapies for acute ischemic myocardial injury and chronic, othe...
Regulators of pluripotency and their implications in regenerative medicine [0.03%]
多潜能性的调控因子及其在再生医学中的意义
Ahmed El-Badawy,Nagwa El-Badri
Ahmed El-Badawy
The ultimate goal of regenerative medicine is to replace damaged tissues with new functioning ones. This can potentially be accomplished by stem cell transplantation. While stem cell transplantation for blood diseases has been increasingly ...
Regenerative medicine in the treatment of idiopathic pulmonary fibrosis: current position [0.03%]
再生医学在特发性肺纤维化治疗中的应用现状
Diana Álvarez,Melanie Levine,Mauricio Rojas
Diana Álvarez
Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible disease of the lung that has no lasting option for therapy other than transplantation. It is characterized by replacement of the normal lung tissue by fibrotic scarring, hon...
Irma Virant-Klun
Irma Virant-Klun
In spite of generally accepted dogma that the total number of follicles and oocytes is established in human ovaries during the fetal period of life rather than forming de novo in adult ovaries, some new evidence in the field challenges this...