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期刊名:Oncotargets and therapy

缩写:ONCOTARGETS THER

ISSN:1178-6930

e-ISSN:1178-6930

IF/分区:2.8/Q2

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Niels W C J van de Donk,Nizar J Bahlis,Charlotte Pawlyn et al. Niels W C J van de Donk et al.
Although recent decades have seen continued improvements in survival for patients with multiple myeloma, the disease remains largely incurable, and most patients will experience relapse and/or become refractory to treatment. There thus rema...
Guolin Ke,Tao Yuan,Chen Wu et al. Guolin Ke et al.
Background: Actinic keratosis (AK), a UV-induced precancerous skin condition potentially progressing to cutaneous squamous cell carcinoma (cSCC) with undefined mechanisms, was analyzed for neutrophil extracellular traps (...
Reham M Alahmadi,Halah Z Al Rawi,Maaweya Awadalla et al. Reham M Alahmadi et al.
Introduction: Every two minutes, a woman dies from cervical cancer, which is considered the fourth most common cancer among women worldwide. The dynamic interplay between tumor inflammation, immune crosstalk, oncogenes, a...
Wei Qiu,Ke Zhang,Wei Hu et al. Wei Qiu et al.
Introduction: Gastric cancer (GC) remains one of the leading causes of cancer-related deaths worldwide, characterized by complex pathogenesis and poor prognosis. Migrasomes, as newly discovered organelles, play crucial ro...
Yan Zhang,Jing Wu,Huaizhong Cui et al. Yan Zhang et al.
Background: Liver cancer ranks among the most prevalent and lethal malignancies worldwide, with metastatic malignant ascites being a common complication. This study seeks to assess the diagnostic significance of high fluo...
Yuning Dai,Yong Yang,Xiaohua Li et al. Yuning Dai et al.
Background: Several malignant tumors have been shown to overexpress aldolase A (ALDOA), a crucial enzyme in the glycolytic cycle. Though, it is still unknown how ALDOA contributes to breast cancer (BC). ...
Rita Carrilho Pichel,Lavinia Benini,Marco Romelli et al. Rita Carrilho Pichel et al.
Lung neuroendocrine tumors (NETs) are well-differentiated neuroendocrine neoplasms of lung origin, including typical and atypical carcinoids (ACs). Therapeutic options for this rare disease are limited in daily clinical practice. Immune-che...
Hao Wang,Zhongquan Yi,Song Yan et al. Hao Wang et al.
ORMDL proteins (ORMDL1, ORMDL2, ORMDL3) are transmembrane proteins in the endoplasmic reticulum (ER) that regulate sphingolipid metabolism, maintain ER homeostasis, and modulate cellular stress responses. They influence cell proliferation, ...
Jordi Martínez-Serra,Aser Alonso-Carballo,Ángel Horrillo et al. Jordi Martínez-Serra et al.
Background: Internal tandem duplications (FLT3-ITDs) in the FLT3 gene constitute a key driver mutation in acute myeloid leukemia (AML), strongly associated with poor prognosis and therapeutic resistance. Although general-...