Real-World Experience of Niraparib as Maintenance Therapy in Patients with Newly Diagnosed Advanced Ovarian Cancer: A Single-Center Retrospective Study [0.03%]
尼拉帕利作为新诊断的晚期卵巢癌维持治疗的单中心回顾性研究现实世界经验分析
Wenxin Liu,Li Zhang,Huijuan Wu et al.
Wenxin Liu et al.
Objective: This study aimed to evaluate the efficacy and safety of niraparib as a maintenance treatment for newly diagnosed advanced ovarian cancer in a real-world setting. ...
Metastatic Laryngeal Minor Salivary Gland Carcinoma to the Liver: Successful Treatment with Anti-EGFR-Based Combination Therapy - A Case Report and Literature Review [0.03%]
抗EGFR联合治疗转移性喉部小涎腺癌成功的病例报告及文献回顾
Zhigui Guo,Qianwen Li,Dan Hong et al.
Zhigui Guo et al.
Laryngeal minor salivary gland carcinoma is a rare malignancy, accounting for less than 1% of laryngeal cancers. We present a case of a 43-year-old male with a history of surgically resected laryngeal ductal carcinoma who developed liver me...
Evaluating the Prognostic Value of a Pan-Cancer Circulating Tumor DNA Next-Generation Sequencing Panel in Advanced Cancer Patients [0.03%]
泛癌种循环肿瘤DNA下一代测序谱板对晚期癌症患者预后价值的评估
Jaewoong Lee,Jang Ho Cho,Seungok Lee et al.
Jaewoong Lee et al.
Purpose: This study aimed to evaluate the clinical utility of a pan-cancer circulating tumor DNA (ctDNA) next-generation sequencing (NGS) panel for predicting treatment response and progression-free survival (PFS) in pati...
Personalized Treatment for Invasive Ductal Breast Carcinoma with Lung and Liver Metastases Based on Patient-Derived Organoids: A Case Report [0.03%]
基于患者来源类器官的侵袭性导管乳腺癌伴肺和肝转移的个性化治疗：病例报告
Miaoli Zheng,Liang Yao,Na Jing et al.
Miaoli Zheng et al.
Patient-derived organoids (PDOs) are emerging as a potential preclinical tool in assessing cancer patients' responses to various therapies. Here, we first described a case of invasive ductal breast carcinoma with lung and liver metastases w...
L-Sarcolysine Reduced the Mobility of Human Glioblastoma Cells, with Potential Involvement of Vimentin [0.03%]
L-肉毒碱减少人胶质母细胞瘤细胞迁移能力及其对波形蛋白的潜在影响
Parastoo Azadbeigi,Negin Moosavinejad,Fatemeh B Rassouli
Parastoo Azadbeigi
Background: Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with poor prognosis, highlighting the need for novel therapeutic approaches. Vimentin plays a critical role in cancer cell motility, with elevat...
Advances in the Use of Immune Checkpoint Inhibitors for Colorectal Cancer Treatment [0.03%]
免疫检查点抑制剂用于结直肠癌治疗的研究进展
Jianing Li,Tong Fu,Zhu Wen et al.
Jianing Li et al.
Purpose: Colorectal cancer (CRC) is a highly prevalent malignant tumor worldwide, and the emergence of immune checkpoint inhibitors (ICIs) has changed CRC immunotherapy. This systematic review aims to provide a comprehens...
Analysis and Exploration of the Relationship Between the Status of Serum Tumor Markers and Clinicopathological Features and Curative Effects in Gastric Cancer and Gastroesophageal Junction Tumor [0.03%]
胃癌及胃食管结合部肿瘤血清肿瘤标志物状态与临床病理特征和疗效关系的分析和探索
Yifan Xiao,Zhenzhu Xing,Zhaobing Li et al.
Yifan Xiao et al.
Background: The detection of tumor markers for predicting the therapeutic efficacy is relatively rare at present. The combined elevation of carcinoembryonic antigen (CEA), CA19-9, CA72-4, and CA125 and others may predict ...
Precision Nanomedicine for Cancer: Innovations, Strategies, and Translational Challenges [0.03%]
癌症精准纳米医学：创新、策略与转化挑战
Fuxing Wen,Lishuang Wang,Xian Li et al.
Fuxing Wen et al.
As nanotechnology advances rapidly, it has propelled nanomedicine into a revolutionary frontier for anticancer therapy. This review comprehensively analyzes the core principles, key innovations, and strategic approaches driving the developm...
Development of a Prognostic m6A-Related lncRNA Signature and Functional Validation of FAM83A-AS1 in Lung Adenocarcinoma [0.03%]
开发肺腺癌预后m6A相关lncRNA标志物及FAM83A-AS1功能验证
Guojun Zhang,Cheng Liu,Yukun Wang
Guojun Zhang
Introduction: This work aimed to identify m6A-related long non-coding RNAs (lncRNAs) associated with lung adenocarcinoma (LUAD) and evaluate their prognostic value and to examine the oncogenic actions of FAM83A-AS1 in LUA...
Ebp1 p48 Promotes Oncogenic Properties in Non-Small Cell Lung Cancer Through PI3K/Akt Signaling Pathways [0.03%]
Ebp1 p48通过PI3K/Akt信号通路促进非小细胞肺癌的致癌特性
Lina Ma,Shuyuan Wang,Jia Zhang et al.
Lina Ma et al.
Purpose: Lung cancer, particularly non-small cell lung cancer (NSCLC), is highly deadly globally. The potential carcinogenic role of p48, a long isoform of ErbB3-binding protein 1 (Ebp1), is well established in other canc...