Secondary Nasopharyngeal Mixed Adenoneuroendocrine Carcinoma After Radical Radiotherapy for Nasopharyngeal Carcinoma: A Rare Case and Literature Review [0.03%]
根治性放疗后继发鼻咽部混合型腺神经内分泌癌一例及文献复习
Donglan Huang,Chunyue Huang,Hongmei Wang et al.
Donglan Huang et al.
The incidence of primary mixed adenoneuroendocrine carcinoma (MANEC) is rapidly increasing. MANEC mainly arises from the gastrointestinal tract, but occasionally it occurs as a pathological type of second primary malignancy (SPM). These SPM...
Promising Molecular Targets for the Targeted Therapy of Biliary Tract Cancers: An Overview [0.03%]
胆道癌靶向治疗的分子标志物研究进展概述
Wenwei Yang,Yongkun Sun
Wenwei Yang
Biliary tract cancer (BTC) is a leading cause of cancer-related death, due to the limited benefits of current systematic therapies and the heterogeneity of the tumor itself. High heterogeneity means that the clinical and molecular features ...
Downregulation of LncRNA DARS-AS1 Inhibits the Tumorigenesis of Cervical Cancer via Inhibition of IGF2BP3 [0.03%]
长链非编码RNA DARS-AS1通过抑制IGF2BP3抑制宫颈癌的发生发展
Jinming Zhu,Shichao Han
Jinming Zhu
Background: Evidence has been shown that long noncoding RNAs (lncRNAs) play an important role in the development of cervical cancer. Recently, lncRNA DARS-AS1 was reported to be dysregulated in several cancer types; howev...
Near-Infrared Light-Triggered Thermosensitive Liposomes Modified with Membrane Peptides for the Local Chemo/Photothermal Therapy of Melanoma [0.03%]
近红外光触发的温敏型膜多肽修饰脂质体用于局部治疗黑色素瘤
Xinxin Li,Chunsheng Yang,Yingkai Tao et al.
Xinxin Li et al.
Purpose: A near-infrared (NIR)-triggered trans-activating transcriptional activator (TAT)-based targeted drug delivery system for the combined chemo/photothermal therapy of melanoma, namely, TAT-TSL-TMZ (temozolomide)/IR8...
Anti-Proliferative, Pro-Apoptotic, Anti-Migrative and Tumor-Inhibitory Effects and Pleiotropic Mechanism of Theaflavin on B16F10 Melanoma Cells [0.03%]
茶黄素对B16F10黑色素瘤细胞的抗增殖、促凋亡、抗迁移和抑瘤作用及其多效性机制研究
Lei Zhang,Shijie Meng,Bo Yan et al.
Lei Zhang et al.
Purpose: Theaflavin (TF) is a primary pigment of tea, exhibiting anti-proliferative, pro-apoptotic and anti-metastatic activities on cancer cell lines. However, it is unknown whether TF is effective in treating melanoma c...
Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC) [0.03%]
生物信息学分析表明CATHEPSIN G（CTSG）可能是口腔鳞状细胞癌（OSCC）的潜在免疫相关生物标志物
Guang-Zhao Huang,Qing-Qing Wu,Ze-Nan Zheng et al.
Guang-Zhao Huang et al.
Purpose: Plenty of studies showed that the immune system was associated with cancer initiation and progression. This study aimed to explore the prognostic biomarkers from immune-related genes (IRGs) in oral squamous cell ...
Ouabain Exhibited Strong Anticancer Effects in Melanoma Cells via Induction of Apoptosis, G2/M Phase Arrest, and Migration Inhibition [0.03%]
乌头昔通过诱导凋亡、G2 / M期阻滞和迁移抑制在黑色素瘤细胞中表现出强烈的抗癌作用
Lei Wang,Wei Cai,Bing Han et al.
Lei Wang et al.
Background: Malignant melanoma was characterized by insensitive chemotherapy, drug resistance, and high metastatic ability, which resulted in the main reason for the mortality among skin-related cancers. The current agent...
MicroRNA-1249 Targets G Protein Subunit Alpha 11 and Facilitates Gastric Cancer Cell Proliferation, Motility and Represses Cell Apoptosis [0.03%]
微小核糖核酸1249通过靶向G蛋白亚基α11促进胃癌细胞增殖、迁移并抑制细胞凋亡的功能研究
Hongzhu Zhang,Tingting Fu,Cuiping Zhang
Hongzhu Zhang
Aim: The purpose of our study was to investigate the effects of miR-1249 in gastric cancer. Methods: By analyzing the data obtained fro...
Actinidia eriantha Polysaccharide and PD1-Antibody Combination Therapy Enhances Antitumor Efficacy in Colorectal Cancer-Xenograft Mice [0.03%]
毛萼野 actinidia eriantha 多糖与 pd-1 抗体联合治疗增强移植瘤裸鼠结直肠癌的抗肿瘤功效
Jinxia Li,Yiping Wang,Weiyang Jin et al.
Jinxia Li et al.
Objective: To observe the efficacy of Actinidia eriantha polysaccharide (AEPS) combined with PD1 antibody therapy in colorectal cancer-xenograft mice. Met...
TRPM2-AS Promotes Bladder Cancer by Targeting miR-22-3p and Regulating GINS2 mRNA Expression [0.03%]
TRPM2-AS通过靶向miR-22-3p并调控GINS2 mRNA表达促进膀胱癌发展
Yudong Tian,Yanbin Guan,Yang Su et al.
Yudong Tian et al.
Background: Bladder cancer (BLCA) refers to the malignancy growth that spreads from the bladder linings to the bladder muscles. However, the impact of miR-22-3p and lncRNA TRPM2-AS on this tumor has generated divergent vi...