Estrogen-Related Receptors Gene Expression and Copy Number Alteration Association With the Clinicopathologic Characteristics of Breast Cancer [0.03%]
雌激素受体基因表达及拷贝数变异与乳腺癌临床病理特征的关系研究
Aymen Shatnawi,Nehad M Ayoub,Amer E Alkhalifa et al.
Aymen Shatnawi et al.
Purpose: It has been suggested that dysregulation of transcription factors expression or activity plays significant roles in breast cancer (BC) severity and poor prognosis. Therefore, our study aims to thoroughly evaluate...
First-Line Treatment of HER2-Positive Metastatic Breast Cancer With Dual Blockade Including Biosimilar Trastuzumab (SB3): Population-Based Real-World Data From the DBCG [0.03%]
基于人群的现实世界数据：HER2阳性转移性乳腺癌一线治疗中包含生物仿制药Trastuzumab（SB3）的双靶治疗(DBCG)
Alan Celik,Tobias Berg,Lise Birk Nielsen et al.
Alan Celik et al.
Purpose: Dual blockade with trastuzumab and pertuzumab in combination with chemotherapy is the recommended first-line therapy for human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (mBC). Th...
Combining Carbon-Ion Irradiation and PARP Inhibitor, Olaparib Efficiently Kills BRCA1-Mutated Triple-Negative Breast Cancer Cells [0.03%]
碳离子照射与PARP抑制剂奥拉帕尼有效杀死BRCA1突变型三阴性乳腺癌细胞
Miki Kawanishi,Mayumi Fujita,Kumiko Karasawa
Miki Kawanishi
Background: Triple-negative breast cancer (TNBC) exhibits poor prognosis due to the lack of targets for hormonal or antibody-based therapies, thereby leading to limited success in the treatment of this cancer subtype. Pol...
Overview of MicroRNA Expression in Predicting Response to Neoadjuvant Therapies in Human Epidermal Growth Receptor-2 Enriched Breast Cancer - A Systematic Review [0.03%]
微小核糖核酸表达对人表皮生长因子受体丰富型乳腺癌新辅助治疗反应预测的影响：系统性回顾
Matthew G Davey,Martin S Davey,Vinitha Richard et al.
Matthew G Davey et al.
Purpose: Increased appreciation of the human epidermal growth factor receptor-2 (HER2/neu) signalling pathway has led to the development of targeted therapeutic agents used in conjunction with chemotherapy to improve outc...
Metabolic Syndrome and Breast Cancer Molecular Subtypes: An Observational Patient Study [0.03%]
代谢综合征与乳腺癌分子亚型：一项观察性患者研究
Dafina Ademi-Islami,Suzana Manxhuka-Kerliu,Dhurata Tarifa-Koroveshi et al.
Dafina Ademi-Islami et al.
Background: Breast cancer molecular subtypes share various prognostic profiles, and luminal A molecular subtypes have a better prognosis compared with other molecular subtypes. However, whether metabolic syndrome or indiv...
Prognostic Significance of Lobular Carcinoma In-Situ (LCIS) Diagnosed Alongside Invasive Breast Cancer [0.03%]
与侵袭性乳腺癌伴发的小叶原位癌(LCIS)的预后意义
Maxwell C Braasch,Amanda L Amin,Christa R Balanoff et al.
Maxwell C Braasch et al.
Purpose: Women with lobular carcinoma in-situ (LCIS) have an increased risk for developing breast cancer (BC) compared with the general population. However, little is known about the clinical implication of diagnosing LCI...
Karanahan: A Potential New Treatment Option for Human Breast Cancer and Its Validation in a Clinical Setting [0.03%]
卡拉那罕：人类乳腺癌的潜在新治疗选择及其临床验证研究
Anastasia S Proskurina,Victoria V Kupina,Yaroslav R Efremov et al.
Anastasia S Proskurina et al.
Introduction: Karanahan, a cancer treatment technology aimed at eradicating tumor-initiating stem cells, has already proven effective in 7 tumor models. Karanahan comprises the following procedures: (1) collecting surgica...
Shiga-Like Toxin Produced by Local Isolates of Escherichia coli O157:H7 Induces Apoptosis of the T47 Breast Cancer Cell Line [0.03%]
志贺毒素样毒素诱导T47乳腺癌细胞系凋亡
Komang Januartha Putra Pinatih,I Wayan Suardana,Dyah Ayu Widiasih et al.
Komang Januartha Putra Pinatih et al.
Purpose: It has been suggested that Shiga-like toxins produced by Escherichia coli O157:H7 could be used as novel therapeutic agents against malignant tumors. In addition, the antitumor potency of local isolates from Indo...
Circulating Tumor Cells and Cancer Stem Cells: Clinical Implications in Nonmetastatic Breast Cancer [0.03%]
循环肿瘤细胞和癌干细胞在非转移性乳腺癌中的临床意义
M Sayed,A M Zahran,M S F Hassan et al.
M Sayed et al.
Purpose: Despite the therapeutic advances, disease recurrence remains an ever-present threat to the health and well-being of breast cancer survivors. Assessment of circulating tumor cells (CTCs) and cancer stem cells (CSC...
Cry1Ac Protoxin Confers Antitumor Adjuvant Effect in a Triple-Negative Breast Cancer Mouse Model by Improving Tumor Immunity [0.03%]
Cry1Ac原毒素通过改善肿瘤免疫提高三阴性乳腺癌小鼠模型的抗肿瘤辅助疗效
Roberto Raúl Servin-Garrido,Damaris Ilhuicatzi-Alvarado,Ángel de Jesús Jiménez-Chávez et al.
Roberto Raúl Servin-Garrido et al.
The Cry1Ac protoxin from Bacillus thuringiensis is a systemic and mucosal adjuvant, able to confer protective immunity in different infection murine models and induce both Th1 and TCD8+ cytotoxic lymphocyte responses, which are required to ...