Marina de Tommaso,Claudia Serpino,Vittorio Sciruicchio
Marina de Tommaso
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by progressive involuntary movements, neuropsychiatric disturbances, and cognitive impairment. The use of tetrabenazine (TBZ), a specific inhibitor ...
Broadening the use of antiretroviral therapy: the case for feline leukemia virus [0.03%]
抗逆转录病毒疗法应用范围的扩大：猫白血病病毒的例子
Willie M Greggs rd,Christine L Clouser,Steven E Patterson et al.
Willie M Greggs rd et al.
Antiretroviral drugs have saved and extended the lives of millions of individuals infected with HIV. The major classes of anti-HIV drugs include reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors, and entry/fusion i...
A hospital-based cost minimization study of the potential financial impact on the UK health care system of introduction of iron isomaltoside 1000 [0.03%]
基于医院的英国医疗系统的成本最小化研究：引入右旋糖酐铁1000的潜在财务影响
Sunil Bhandari
Sunil Bhandari
Background: The clinical need to be able to administer high doses of intravenous iron conveniently in a single rapid infusion has been addressed by the recent introduction of ferric carboxymaltose and subsequently iron is...
Inferior vena cava filters in cancer patients: to filter or not to filter [0.03%]
肿瘤患者的下腔静脉滤器置入：置入还是不置入？
Hikmat Abdel-Razeq,Asem Mansour,Yousef Ismael et al.
Hikmat Abdel-Razeq et al.
Purpose: Cancer and its treatment are recognized risk factors for venous thromboembolism (VTE); active cancer accounts for almost 20% of all newly diagnosed VTE. Inferior vena cava (IVC) filters are utilized to provide me...
A causative link between periodontal disease and glomerulonephritis: a preliminary study [0.03%]
牙周病与肾小球肾炎因果关系的初步研究
Mohammad Reza Ardalan,Kamyar Ghabili,Reza Pourabbas et al.
Mohammad Reza Ardalan et al.
Background: Periodontal disease has been associated with a number of systemic diseases. A high prevalence of periodontitis among individuals with chronic kidney diseases and end-stage renal disease has been reported. Howe...
Maria Antonietta Catania,Salvatore Cuzzocrea
Maria Antonietta Catania
Cough constitutes an impressive expression of the normal defense mechanisms of the respiratory system. Productive cough associated with catarrh is an important protective system for the lung because it favors the upward movement of secretio...
Enzyme replacement therapy for Fabry disease: some answers but more questions [0.03%]
法布雷病的酶替代治疗：问题与答案
Majid Alfadhel,Sandra Sirrs
Majid Alfadhel
Fabry disease (FD) is a multisystem, X-linked disorder of glycosphingolipid metabolism caused by enzyme deficiency of α-galactosidase A. Affected patients have symptoms including acroparesthesias, angiokeratomas, and hypohidrosis. More ser...
A new Web-based medical tool for assessment and prevention of comprehensive cardiovascular risk [0.03%]
一个新型的基于网络的心血管风险综合评估和预防的医疗工具
Daniele Franchi,Davide Cini,Giorgio Iervasi
Daniele Franchi
Background: Multifactor cardiovascular disease is the leading cause of death; besides well-known cardiovascular risk factors, several emerging factors such as mental stress, diet type, and physical inactivity, have been a...
Anorexia nervosa versus hyperinsulinism: therapeutic effects of neuropharmacological manipulation [0.03%]
神经药理学干预的治疗效果与神经性厌食和高胰岛素血症的关系
Fuad Lechin,Bertha van der Dijs,Betty Pardey-Maldonado et al.
Fuad Lechin et al.
Background: We have demonstrated that anorexia nervosa is underpinned by overwhelming adrenal sympathetic activity which abolishes the neural sympathetic branch of the peripheral autonomic nervous system. This physiologic...
Genitourinary system trauma after 2003 Bam earthquake in Kerman, Iran [0.03%]
伊朗克尔曼2003年巴姆地震后的泌尿系统创伤
Mohammad Hasan,Dehghani Firoozabadi,Mehdi Abedinzadeh et al.
Mohammad Hasan et al.
Background: Natural disasters, especially earthquakes, result in many health problems all over the world, of which urological injuries should not be underestimated. Car accidents and falling from a height are the most com...