Efficacy and Safety of Endoscopic Retrograde Cholangiopancreatography for the Longevous Population [0.03%]
内镜逆行胰胆管造影在高龄人群中的疗效和安全性分析
Jin-Li He,Liang Zhu,Zhen-Zhen Yang et al.
Jin-Li He et al.
Background: There are presently limited clinical studies of endoscopic retrograde cholangiopancreatography (ERCP) in the longevous (elders aged no less than 90 years old). This study aimed to evaluate the efficacy and saf...
Factors Associated with Frailty Transitions Using the Kihon Checklist: A 6-Year Longitudinal Study Among Japanese Residents [0.03%]
基于基hon清单的虚弱状态转换的影响因素——一项为期六年的纵向研究
Norio Imai,Daisuke Homma,Yoji Horigome et al.
Norio Imai et al.
Background: The Kihon Checklist (KCL) is widely used in Japan to assess robustness, pre-frailty, and frailty. However, the specific KCL items that predict the maintenance of robustness or transitions between frailty state...
Comparison of Remimazolam and Sevoflurane on Perioperative Body Temperature Changes in Older Patients Undergoing Transurethral Resection of Prostate or Bladder Tumors Under General Anesthesia: A Randomized Prospective Clinical Trial [0.03%]
右美托咪定和七氟烷对老年患者全身麻醉下经尿道前列腺或膀胱肿瘤电切术围手术期体温变化的影响：一项随机前瞻性临床试验
Jungju Choi,Chungon Park,Kun Hee Lee et al.
Jungju Choi et al.
Purpose: Perioperative hypothermia is a common complication of general anesthesia, especially in older patients undergoing transurethral resection of the prostate (TURP) or bladder tumors (TURB). Age-related thermoregulat...
Randomized Controlled Trial
Clinical interventions in aging. 2025 Oct 25:20:1811-1820. DOI:10.2147/CIA.S549347 2025
Electroacupuncture Plus Exercise for Sarcopenia in Older Adults: Protocol for a Randomized, Controlled, Assessor-Blinded Trial [0.03%]
电针结合运动治疗老年人肌肉减少症的随机对照盲法试验方案
Wenzhe Wu,Xiaohan Huang,Lianqiang Fang et al.
Wenzhe Wu et al.
Background: The therapeutic effect of conventional therapies (eg, resistance training, nutritional support) for treating sarcopenia show limited efficacy in older individuals with multiple comorbidities. Therefore, this s...
Prevalence of Multiple Chronic Conditions in Older Adults with Undiagnosed Mild Cognitive Impairment and Alzheimer's Disease and Related Dementias in Primary Care [0.03%]
初级保健中老年未诊断的轻度认知障碍和阿尔茨海默病及相关痴呆症合并多种慢性疾病患病率
Diana Summanwar,Arthur H Owora,Zina Ben Miled et al.
Diana Summanwar et al.
Background: Most adults aged ≥65 years live with multiple chronic conditions (MCC), and nearly one in four have recognized or unrecognized Alzheimer's disease and related dementias (ADRD), including an estimated 7.2 mill...
Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Postoperative Delirium in Older Adults Undergoing Total Knee Arthroplasty: A Multicenter Randomized Controlled Trial Protocol [0.03%]
耳迷走神经经皮电刺激预防老年全膝关节置换患者术后谵妄的多中心随机对照试验方案研究
Xincheng Liao,Tongtong Zhang,Jingxuan Zhang et al.
Xincheng Liao et al.
Purpose: Postoperative delirium affects up to 65% of elderly surgical patients, leading to increased mortality and cognitive decline. Current prevention strategies face implementation barriers, necessitating accessible, n...
Multimodal Brain Monitoring-Guided Anesthesia Management Improves Functional Connectivity, Enhances Recovery and Attenuates Postoperative Pain in Elderly Surgical Patients [0.03%]
基于多模态脑监测的麻醉管理改善老年患者术后功能连接、促进苏醒及缓解术后疼痛：一项随机对照试验
Shuyi Yang,Shuai Feng,Hao Wu et al.
Shuyi Yang et al.
Purpose: Perioperative neurocognitive disorder (PND) is common in elderly surgical patients and severely affects postoperative recovery. However, effective prevention is still lacking. Potential perioperative cerebral str...
Multidimensional Analysis of Frailty and Its Influencing Factors in Hospitalized Elderly Stroke Patients [0.03%]
住院老年脑卒中患者脆弱性及其影响因素的多维分析
Huimin Zhou,Yan Han,Dan Xie et al.
Huimin Zhou et al.
Background: Frailty is a common geriatric syndrome, and its occurrence in elderly stroke patients may further worsen clinical outcomes, yet the influencing factors and potential causal relationship remain unclear. ...
Multicenter Study
Clinical interventions in aging. 2025 Oct 11:20:1741-1755. DOI:10.2147/CIA.S546975 2025
The Ambiguous Role of HMGB1 Across the Hallmarks of Aging: A Narrative Review [0.03%]
HMGB1在衰老标志中的作用：叙述性综述
Manru Ning,Yihuai Liang,Liu Zhang et al.
Manru Ning et al.
Aging is a complex, multifactorial process driven by interconnected biological mechanisms collectively known as the hallmarks of aging, which contribute to functional decline and the onset of age-related diseases. High-mobility group box 1 ...