Postoperative Serum NLRP1 as a Biochemical Predictor of Delirium and Cognitive Decline After Hip Fracture Surgery in Elderly Patients: A Single Center Observational Study [0.03%]
术后血清NLRP1作为预测老年患者髋部骨折手术后谵妄和认知衰退的生化标志物:一项单中心观察性研究
Liuqing Wu,Yu Li,Li Li et al.
Liuqing Wu et al.
Objective: Postoperative delirium (POD) and cognitive decline (POCD) are linked to inflammatory brain injury, and nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 1 (NLRP1) participat...
Observational Study
Clinical interventions in aging. 2025 Nov 13:20:2005-2017. DOI:10.2147/CIA.S556318 2025
Contezolid for the Super-Elderly: Balancing Efficacy and Safety Through Pharmacokinetic Insights [0.03%]
康扎替南治疗超高龄患者:通过药代动力学洞察平衡疗效和安全性的研究
Tingting Liu,Beibei Liang,Bing Liu et al.
Tingting Liu et al.
Background: Contezolid is a new oxazolidinone antibacterial agent, and its pharmacokinetic (PK) characteristics and safety in super-elderly patients remain poorly understood. ...
Effects of Multicomponent Otago Exercise Program with Added Resistance Training on Sarcopenia in Pre-Frailty Older Adults in Nursing Homes: A Randomized Controlled Trial [0.03%]
多成分奥塔哥锻炼方案联合阻抗训练对护理院前虚弱老年人肌少症的影响:一项随机对照试验
Neng Pan,Yan Chen,Zhaojian Wang et al.
Neng Pan et al.
Background: The Otago Exercise Program (OEP) is suitable for frail older adults but has limited effect on sarcopenia. Resistance training (RT) is commonly used for sarcopenia. This study evaluated the effects of 12 weeks ...
Balance and Gait Disorders in the Aged Population. Causes, Assessment and Management: A Literature Review [0.03%]
老年人平衡及步态障碍的原因、评估与治疗:文献回顾
Patrick Manckoundia,France Mourey,Fabrice Larosa et al.
Patrick Manckoundia et al.
With aging, compensatory mechanisms and physiological reserve may become insufficient to maintain balance and gait (BG), particularly when associated with stroke, Alzheimer's disease, diabetes, osteoarticular diease, vestibular disorders, o...
Prognostic Value of Glucose-to-Potassium Ratio in Acute Ischemic Stroke Patients Undergoing Thrombolysis and Its Interaction with Inflammation [0.03%]
急性缺血性卒中溶栓患者葡萄糖-钾比值的预后价值及其与炎症的交互作用
Lingling Lin,Rui Zhang,Jianing Wang et al.
Lingling Lin et al.
Objective: The glucose-to-potassium ratio (GPR) has been proven to be an early predictor of central nervous system injury. Meanwhile, it has a potential interaction with the inflammatory response. Therefore, we aimed to c...
Evaluation of Potential Drug-Drug Interactions, Polypharmacy, and Prescribing Patterns of NSAIDs Among the Older Adults in a Secondary Care Setting [0.03%]
社区老年患者用药评估及非甾体抗炎药的处方模式分析
Javedh Shareef,Sathvik Belagodu Sridhar,Zainab Mohammed Saeed et al.
Javedh Shareef et al.
Purpose: In clinical practice, non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed to older adults patients for pain and inflammation. However, drug therapy in this population carries risks of polypharmac...
Observational Study
Clinical interventions in aging. 2025 Nov 5:20:1875-1894. DOI:10.2147/CIA.S545906 2025
Risk Factors for Acute Heart Failure in Older Adults with Hip Fractures After Surgery and Construction of a Nomogram Predictive Model [0.03%]
老年髋部骨折术后急性心力衰竭的风险因素分析及预测模型的建立
Siyu Zhang,Dong Sun,Lingxiao Wang et al.
Siyu Zhang et al.
Purpose: The frequency of acute heart failure (AHF) is relatively high in older adults undergoing hip fracture surgery. This study aims to explore the possible risk factors and create a nomogram predictive model for quant...
Current Status and Determinants of Fatigue in Chinese Older Adults Receiving Maintenance Hemodialysis: A Multicentre Cross-Sectional Study [0.03%]
中国维持性血液透析老年患者疲劳状况及其影响因素的多中心横断面研究
Na Zhang,Peng Jiang,Siyu Fan et al.
Na Zhang et al.
Background: Fatigue is highly prevalent in older adults receiving maintenance hemodialysis and seriously affects quality of life. However, evidence on the current status of fatigue and its determinants in this population ...
Effect of Different Neuromuscular Electrical Stimulation Modalities on Clinical and Functional Outcomes in Older Adults with Knee Osteoarthritis: A Randomized Controlled Trial [0.03%]
不同神经肌肉电刺激对膝关节骨关节炎老年人临床和功能结局影响的随机对照试验
Camila Cadena De Almeida,Klaus Porto Azevedo,José Roberto De Souza Júnior et al.
Camila Cadena De Almeida et al.
Introduction: Osteoarthritis (OA) is a chronic degenerative disease characterized by progressive cartilage degeneration, most commonly affecting the knee. Clinical symptoms such as pain, stiffness, and functional limitati...