High Rate of Non-detectable HIV-1 RNA Among Antiretroviral Drug Naive HIV Positive Individuals in Nigeria [0.03%]
尼日利亚抗逆转录病毒药物新手的HIV阳性个体中未检出HIV-1 RNA的比例较高
Georgina N Odaibo,Isaac F Adewole,David O Olaleye
Georgina N Odaibo
Plasma HIV-1 RNA concentration, or viral load, is an indication of the magnitude of virus replication and largely correlates with disease progression in an infected person. It is a very useful guide for initiation of therapy and monitoring ...
Antigenic Variation in H5N1 clade 2.1 Viruses in Indonesia From 2005 to 2011 [0.03%]
2005-2011年印度尼西亚H5N1禽流感2.1进化分支的抗原变异分析
Vivi Setiawaty,Eka Pratiwi,Hana A Pawestri et al.
Vivi Setiawaty et al.
Influenza A (H5N1) virus, has spread to several countries in the world and has a high mortality rate. Meanwhile, the virus has evolved into several clades. The human influenza A (H5N1) virus circulating in Indonesia is a member of clade 2.1...
Dendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle? [0.03%]
HIV-1和HCV感染中的树突状细胞：它们能帮助取得胜利吗？
Mohit Sehgal,Zafar K Khan,Andrew H Talal et al.
Mohit Sehgal et al.
Persistent infections with human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) are a major cause of morbidity and mortality worldwide. As sentinels of our immune system, dendritic cells (DCs) play a central role in initi...
Ana L Gervassi,Helen Horton
Ana L Gervassi
Almost 7 million children under the age 5 die each year, and most of these deaths are attributable to vaccine-preventable infections. Young infants respond poorly to infections and vaccines. In particular, dendritic cells secrete less IL-12...
Katarzyna Kaczmarek,Ayana Morales,Andrew J Henderson
Katarzyna Kaczmarek
By targeting CD4+ effector T cells, HIV has a dramatic impact on the depletion, expansion and function of the different polarized T cell subsets. The maturation of T cell lineages is in part driven by intrinsic transcription factors that po...
Identification of Rotavirus VP6-Specific CD4+ T Cell Epitopes in a G1P[8] Human Rotavirus-Infected Rhesus Macaque [0.03%]
用人轮状病毒G1P[8]感染的恒河猴模型鉴定Rotavirus VP6特异性CD4+T细胞表位
Wei Zhao,Bapi Pahar,Karol Sestak
Wei Zhao
A non-human primate model was used to evaluate its potential for identification of rotavirus viral protein 6 (VP6) CD4+ T cell epitopes. Four juvenile rhesus macaques were inoculated with a mixed inoculum (G1P[8] and G9P[8]) of human rotavi...
HIV-1 Transmission, Replication Fitness and Disease Progression [0.03%]
人类免疫缺陷病毒-1的传播、复制适配性和疾病发展进程之间的关系研究
Tasha Biesinger,Jason T Kimata
Tasha Biesinger
Upon transmission, human immunodeficiency virus type 1 (HIV-1) establishes infection of the lymphatic reservoir, leading to profound depletion of the memory CD4(+) T cell population, despite the induction of the adaptive immune response. Th...