T E Hardingham,V Rayan,J C Lewthwaite
T E Hardingham
Articular cartilage has important load bearing properties. These depend on the integrity of its matrix which is formed by a dense network of collagen fibres (mainly type II) and a high concentration of proteglycan (mainly aggrecan). The mat...
R D Altman
R D Altman
B Delcambre,A Taccoen
B Delcambre
M Lequesne
M Lequesne
A number of compounds have "chondroprotective" effects in animals or chondrocyte cultures. However, in humans, these drugs have not been convincingly shown to prevent, delay, arrest, or repair structural cartilage lesions due to osteoarthri...
M Dougados,X Ayral,V Listrat et al.
M Dougados et al.
Arthroscopy allows direct visual examination of joint cavity components and is useful for the diagnosis, treatment and evaluation of lesions. We investigated the contribution of arthroscopy to the evaluation of joint cartilage. The severity...
A M Tron,T Conrozier,P Mathieu et al.
A M Tron et al.
Accurate measures of cartilage destruction are needed to evaluate the effects of chondroprotective agents in human osteoarthritis. Use of a digitalized image analyzer (HOLOGIC, ICMS software) to measure mean joint space width on roentgenogr...
S Laoussadi,C J Menkès
S Laoussadi
Although osteoarthritis is characterized by a uniform pattern of clinical and radiological manifestations, it is a syndrome that can be produced by a variety of causative factors. Rare causes of osteoarthritis can be categorized as follows:...
J Martel-Pelletier,J P Pelletier
J Martel-Pelletier
Osteoarthritis (OA) is a degenerative disease of the articular cartilage associated with a variable degree of synovial inflammation which appears to play an important role in the pathophysiological process by interacting with and thereby ac...
[Role of synovial inflammation, cytokines and IGF-1 in the physiopathology of osteoarthritis] [0.03%]
滑膜炎症、细胞因子和IGF-1在骨关节炎生理病理中的作用
J P Pelletier,J Martel-Pelletier
J P Pelletier
The role of cytokines in the progression of arthritic diseases such as osteoarthritis (OA) has received particular attention because of the important interaction between articular cartilage and synovium in the pathology of the diseased stat...
E Toussirot,P Darmon,P C Acquaviva
E Toussirot
Case Reports
Revue du rhumatisme (Ed. francaise : 1993). 1994 Oct;61(9):655. DOI: 1994