Eric Dumonteil
Eric Dumonteil
Over the past 15 years, DNA vaccines have gone from a scientific curiosity to one of the most dynamic research field and may offer new alternatives for the control of parasitic diseases such as leishmaniasis and Chagas disease. We review he...
Immune response regulation by leishmania secreted and nonsecreted antigens [0.03%]
利什曼原虫分泌和非分泌型抗原对免疫反应的调节作用
Nuno Santarém,Ricardo Silvestre,Joana Tavares et al.
Nuno Santarém et al.
Leishmania infection consists in two sequential events, the host cell colonization followed by the proliferation/dissemination of the parasite. In this review, we discuss the importance of two distinct sets of molecules, the secreted and/or...
Expression of VE-Cadherin in Peritubular Endothelial Cells during Acute Rejection after Human Renal Transplantation [0.03%]
人肾移植后急性排斥反应中管周内皮细胞VE-钙黏蛋白的表达
Ana Roussoulières,Brigitte McGregor,Lara Chalabreysse et al.
Ana Roussoulières et al.
Genes involved in acute rejection (AR) after organ transplantation remain to be further elucidated. In a previous work we have demonstrated the under-expression of VE-Cadherin by endothelial cells (EC) in AR following murine and human heart...
Targeted Gene Disruption of the Cyclo (L-Phe, L-Pro) Biosynthetic Pathway in Streptomyces sp. US24 Strain [0.03%]
放线菌US24品系中环(L-苯丙氨酰-L-脯氨酸)生物合成途径的靶基因失活研究
Samiha Sioud,Ines Karray-Rebai,Hedi Aouissaoui et al.
Samiha Sioud et al.
We have previously isolated a new actinomycete strain from Tunisian soil called Streptomyces sp. US24, and have shown that it produces two bioactive molecules including a Cyclo (L-Phe, L-Pro) diketopiperazine (DKP). To identify the structur...
Eisenia fetida protease-III-1 functions in both fibrinolysis and fibrogenesis [0.03%]
>Eisenia fetida蛋白酶-III-1在纤维蛋白溶解和纤维蛋白生成中的作用
Jing Zhao,Rong Pan,Jian He et al.
Jing Zhao et al.
The fibrinolytic function of earthworm protease-III-1 (Ef P-III-1) has been studied in recent years. Here, we found that Ef P-III-1 acted not only in fibrinogenolysis, but also in fibrogenesis. We have used Ef P-III-1 to hydrolyze fibrinoge...
Enhancement of a TH1 immune response in amphotericin B-treated mucocutaneous leishmaniasis [0.03%]
两性霉素B治疗的黏膜皮肤利什曼病TH1免疫反应的增强
Washington R Cuna,Rianed Velasquez,Janeth Riva et al.
Washington R Cuna et al.
In an attempt to investigate the effects of treatment of human leishmaniasis, the cytokines produced by peripheral blood mononuclear cells (PBMCs) of patients with cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL) under tre...
Molecular aspects of Plasmodium falciparum Infection during pregnancy [0.03%]
恶性疟原虫感染的分子机制及其对孕妇的影响研究进展
Nicaise Tuikue Ndam,Philippe Deloron
Nicaise Tuikue Ndam
Cytoadherence of Plasmodium-falciparum-parasitized red blood cells (PRBCs) to host receptors is the key phenomenon in the pathological process of the malaria disease. Some of these interactions can originate poor outcomes responsible for 1 ...
Regulatory cells and immunosuppressive cytokines: parasite-derived factors induce immune polarization [0.03%]
调控细胞和免疫抑制性细胞因子：寄生虫衍生因素诱发的免疫偏向
Ali Ouaissi
Ali Ouaissi
Parasitic infections are prevalent in both tropical and subtropical areas. Most of the affected and/or exposed populations are living in developing countries where control measures are lacking or inadequately applied. Although significant p...
Taghrid B El-Abaseri,Laura A Hansen
Taghrid B El-Abaseri
The epidermal growth factor receptor (EGFR) regulates the proliferation of keratinocytes through multiple mechanisms that differ depending on the localization of the cell within the skin. Ultraviolet (UV) irradiation, the main etiologic fac...
Stem cell fate analysis revisited: interpretation of individual clone dynamics in the light of a new paradigm of stem cell organization [0.03%]
再论干细胞命运分析：以新的干细胞组织理念重新审视单克隆的动态特性
Ingo Roeder,Katrin Braesel,Ronny Lorenz et al.
Ingo Roeder et al.
Many experimental findings on heterogeneity, flexibility, and plasticity of tissue stem cells are currently challenging stem cell concepts that assume a cell intrinsically predefined, unidirectional differentiation program. In contrast to t...