Relation between sirtuin-1 activity and graft-versus-host disease (GVHD) status post allogeneic haematopoietic stem-cell transplantation (HSCT): Prospective study [0.03%]
供体基质细胞来源的外泌体治疗移植物抗宿主病小鼠模型的疗效及其机制研究
Rana G Abdelfatah,Mohamed M Mousa,Nermen A Nabeeh et al.
Rana G Abdelfatah et al.
Graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem-cell transplantation (HSCT). This prospective study investigated the role of sirtuin-1 (Sirt-1) activity in GVHD pathogenesis. Thirty patients post...
The value of interleukin-1 beta (IL-1β) measurement in the detection of bacterial urinary tract infection in symptomatic and asymptomatic bacteriuria patients [0.03%]
检测尿源性细菌感染需不需要测量细胞因子白介素-1β(IL-1β)病毒感染指标?——有症状和无症状患者之间的比较研究
Mariam E E Sarhan,Raafat A Abd Eltwab,Safia A Elgamal et al.
Mariam E E Sarhan et al.
Urinary tract infections (UTIs) are common bacterial infections, while asymptomatic bacteriuria involves bacterial presence without symptoms. Diagnosing UTIs can be challenging, leading to complications or antibiotic misuse. Interleukin-1 b...
Inflammatory markers in end-stage renal disease patients on maintenance hemodialysis, hemodiafiltration (HDF), early post-renal transplant patients, and their relation to quality of life (SGA Score) [0.03%]
维持性血液透析、血液透析滤过(HDF)患者、肾移植术后早期患者的终末期肾病患者炎症标志物及其与生活质量(SGA评分)的关系
Hesham ElSayed,Aber Halim,Abdelrahman Elbraky et al.
Hesham ElSayed et al.
Chronic kidney disease (CKD) is associated with malnutrition-inflammation-atherosclerosis (MIA) syndrome, persistent inflammation, and protein-energy wasting, which adversely affect nutritional status and quality of life. High-sensitivity C...
Peripheral blood inflammatory cell ratios derived from complete blood count as predictors of multiple sclerosis disease activity and severity [0.03%]
基于外周血常规的炎症细胞比值作为预测多发性硬化病活动度和严重性的标志物研究
Nouran M Moustafa,Hasan Alahmed,Omar Mahgoub et al.
Nouran M Moustafa et al.
Multiple sclerosis (MS) is an autoimmune disorder affecting the central nervous system. This retrospective cohort study analyzed medical records of 98 MS patients to evaluate the predictive role of neutrophil-to-lymphocyte ratio (NLR), mono...
Investigating correlation between microRNA-146a gene expression and TNF-α levels among rheumatoid arthritis patients in Babylon province [0.03%]
巴比伦省类风湿关节炎患者中微小核糖核酸-146a基因表达与肿瘤坏死因子-α水平相关性的研究
Zainab N Nabat,Mahdi H Alammar
Zainab N Nabat
Rheumatoid arthritis (RA) is a progressive autoimmune disorder driven by immune cell and cytokine interactions. This case-control study investigated microRNA-146a (miRNA-146a) and tumor necrosis factor-alpha (TNF-α) as prognostic markers i...
Evaluation of CD19+ CD24+CD27 B cell and serum level of interleukin 10 and interleukin 35 in patients with systemic lupus erythematosus [0.03%]
系统性红斑狼疮患者CD19+CD24+CD27B细胞及血清IL-10、IL-35水平检测及其临床意义分析
Nashwa S M Abdeen,Reham M A Abdalla,Heba M A Abdalla et al.
Nashwa S M Abdeen et al.
Regulatory B cells (Bregs) maintain immune homeostasis through anti-inflammatory cytokine production, yet their role in systemic lupus erythematosus (SLE) remains poorly understood. This study evaluated CD19+CD24highCD27+ B cell frequencies...
Immune cytokine imbalance and hematological disturbances in systemic lupus erythematosus patients [0.03%]
系统性红斑狼疮患者的免疫细胞因子失衡及血液学异常
Safa S Fayez,Rana T Mohsen,Al-Moghira K Al-Qaysi
Safa S Fayez
Lupus nephritis is a severe condition that develops due to immune complex deposition on renal tissues, contributing to disease progression and long-term complications. This study assessed 40 systemic lupus erythematosus (SLE) patients and 4...
Trichinella spiralis - induced modulation of IFN-γ and TGF-β shapes host immunity to support chronic infection [0.03%]
旋毛虫诱导的IFN-γ和TGF-β的变化形塑宿主免疫系统以支持慢性感染
Alaa F A Elsaid,Ibrahim R Shalash,Mona M El-Derbawy et al.
Alaa F A Elsaid et al.
Trichinella spiralis is a widely prevalent foodborne helminth that establishes chronic infection through modulation of host immunity. This study investigated the temporal dynamics of interferon-γ (IFN-γ), transforming growth factor-β (TG...
Post-covid-19 immune signatures: Antibody and Th1 cytokine profiles among healthcare workers in Côte d'Ivoire [0.03%]
新冠后免疫特征:科特迪瓦医护人员的抗体和Th1细胞因子谱型
Amah P V Goran-Kouacou,Séry R Dassé,Adjoumanvoulé H Adou et al.
Amah P V Goran-Kouacou et al.
The post-SARS-CoV-2 immune response involves both neutralizing antibodies (NAbs) and T-cell cooperation. Healthcare workers, highly exposed in daily practice, represent a relevant population for study. This study aimed to describe the post-...
Diagnostic value of serum lipocalin-2 in Egyptian patients with inflammatory bowel disease: A case-control study [0.03%]
埃及炎症性肠病患者血清脂运蛋白-2的诊断价值:一项病例对照研究
Mina W N Abd El Malak,Noha A El Nakeeb,Mohamed A Abo Daif et al.
Mina W N Abd El Malak et al.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), often presents diagnostic challenges. Lipocalin-2 (LCN-2) has emerged as a potential biomarker for intestinal inflammation. This study aimed to...