Clinical study of cetuximab combined with radical radiotherapy in the treatment of locally advanced sinonasal squamous cell carcinoma [0.03%]
吉西他滨联合根治性放疗治疗局部晚期鼻腔鼻窦鳞癌的临床研究
Xianben Qiu,Jie Yang
Xianben Qiu
Purpose: To observe the efficacy and side effects of cetuximab combined with radical radiotherapy in the treatment of sinonasal squamous cell carcinoma (SCC), and to investigate the underlying mechanism of cetuximab. ...
Immunohistochemical expression of proliferative markers in renal cell carcinoma [0.03%]
肾细胞癌增殖标记的免疫组化表达
Jovanka Trifunovic,Mirjana Prvanovic,Aleksandar Jovanovic et al.
Jovanka Trifunovic et al.
Purpose: The purpose of this study was to investigate into the expression of cyclin A and telomerase in renal cell carcinoma (RCC) and to analyze the relationship between expression and the clinicopathological characteris...
Correlation of VEGF and EGFR in peripheral blood with clinical stage and pathological grade of renal cell carcinoma and analysis of prognosis [0.03%]
VEGF和EGFR在肾细胞癌外周血中的表达及其与临床分期、病理分级的关系及预后分析
Chenlong Chu,Caifeng Lu,Zhaohui Zhang et al.
Chenlong Chu et al.
Purpose: To detect the expression of VEGF and EGFR in peripheral blood and cancer tissues of patients with renal cell carcinoma (RCC), and to explore the correlations with clinical stage, pathological grade and prognosis ...
Tanshinone l exhibits anticancer effects in human endometrial carcinoma HEC-1-A cells via mitochondrial mediated apoptosis, cell cycle arrest and inhibition of JAK/STAT signalling pathway [0.03%]
丹参酮L通过线粒体介导的细胞凋亡、周期阻滞和抑制JAK/STAT信号途径对人类子宫内膜癌HEC-1-A细胞具有抗肿瘤作用
Qian Li,Jing Zhang,Ying Liang et al.
Qian Li et al.
Purpose: Tanshinone I is an important plant-derived natural product that has been reported to exert impressive bioactivities, including antiproliferative effects against different types of cancer cells. In this study the ...
Knockdown of mutated ARID1A inhibited endometrial cancer cell proliferation and stimulated cell apoptosis [0.03%]
ARID1A基因敲低抑制子宫内膜癌细胞增殖并促进细胞凋亡
Yang Ye,Bao Wei,Xi Xiaowei
Yang Ye
Purpose: Mutations in the gene encoding the AT-rich interacting domain containing protein 1A (ARID1A) are frequently observed in endometrial cancer, although the molecular mechanisms linking the genetic changes remain poo...
Circulating tumor cells predict prognosis following secondline AZD 9291 treatment in EGFR-T790M mutant non-small cell lung cancer patients [0.03%]
二线应用AZD9291治疗的EGFR T790M突变型非小细胞肺癌患者循环肿瘤细胞与预后相关性研究
Baohong Yang,Dejie Zheng,Υanyan Zeng et al.
Baohong Yang et al.
Purpose: AZD9291 has been developed as third-generation epithermal growth factor receptor (EGFR)- tyrosine kinase inhibitor (TKI) with activities against T790M mutation. This study aimed to isolate and quantify the circul...
Biweekly cisplatin and gemcitabine with two different doses in non small cell lung cancer patients: A retrospective singlecenter experience [0.03%]
两种剂量的每两周一次的顺铂和吉西他滨治疗非小细胞肺癌患者：一项单中心回顾性研究
Ender Dogan,Mahmut Ucar,Teoman Sakalar et al.
Ender Dogan et al.
Purpose: Non-small-cell lung cancer (NSCLC) constitutes 80-85% of all lung cancers. Patients with advanced-stage NSCLC may benefit from chemotherapy. Gemcitabine and cisplatin is a well-established therapy for this malign...
Interobserver agreement in prostate cancer detection using multiparametric MRI [0.03%]
前列腺癌多参数MRI诊断的观察者间一致性分析
Cristian Popita,Anca-Raluca Popita,Adina Andrei et al.
Cristian Popita et al.
Purpose: The purpose of this prospective observational study was to evaluate the diagnostic performance of multiparametric (mp) magnetic resonance imaging (MRI) for prostate cancer detection and to assess the interobserve...
Royleanone diterpenoid exhibits potent anticancer effects in LNCaP human prostate carcinoma cells by inducing mitochondrial mediated apoptosis, cell cycle arrest, suppression of cell migration and downregulation of mTOR/PI3K/AKT signalling pathway [0.03%]
罗伊烷酮二萜通过诱导线粒体介导的细胞凋亡、细胞周期阻滞、抑制细胞迁移和下调mTOR/PI3K/AKT信号通路在人前列腺癌LNCaP细胞中表现出强大的抗癌作用
Xiaoming Wu,Yi He,Gaoyue Zhang et al.
Xiaoming Wu et al.
Purpose: Prostate cancer is a deadly malignancy and is responsible for significant cancer-related mortality in men. The incidence of prostate cancer is continuously increasing across the globe and the existing treatment o...
Multifocality as independent prognostic factor in papillary thyroid cancer - A multivariate analysis [0.03%]
多灶性作为乳头状甲状腺癌独立预后因素的多变量分析
Ivan Markovic,Merima Goran,Nikola Besic et al.
Ivan Markovic et al.
Purpose: The incidence of multifocality of papillary thyroid carcinoma (PTC) ranges from 18 to 87.5% The mechanisms of multifocal spreading, correlation with tumor size, histology variants of PTC, lymph node metastases, a...