miR-125a Serves a Diagnostic Biomarker in Patients With Carotid Artery Stenosis and Predicts the Occurrence of Cerebral Ischemic Event [0.03%]
miR-125a可作为颈动脉狭窄患者的诊断标志物并预测脑缺血事件的发生
Qianjin Ding,Lijun Niu,Chenguang Tong
Qianjin Ding
The study was to evaluate the diagnostic significance of serum miR-125a in individuals with carotid artery stenosis (CAS) and its predictive capacity for cerebral ischemic events (CIEs). This study enrolled 116 healthy controls and 122 CAS ...
The Extracellular Matrix Agrin Promotes Epicardial Cells Activation and Proliferation Post Myocardial Infarction in Mice [0.03%]
基底膜糖蛋白Agrin通过促进梗死后心外膜细胞活化和增殖修复心脏损伤
Yue Han,Dinghui Wang,Huiping Yang et al.
Yue Han et al.
The extracellular matrix protein (ECM) Agrin could facilitate cardiac regeneration and repair after myocardial infarction (MI), but its specific impacts on epicardial cells (EpiCs) remains unexplored. To investigate Agrin's influence on the...
Tanshinol: A Potential Antioxidant, Anti-Inflammatory Agent, and a Potent Apoptosis Inducer in Non-Small Cell Lung Cancer Cells [0.03%]
丹参茋：一种潜在的抗氧化剂、抗炎剂和非小细胞肺癌细胞中的强凋亡诱导剂
Ningwei Zhu,Xueying Yao,Lisuhang Guo et al.
Ningwei Zhu et al.
Advances in therapy have yet to substantially improve the 5-year survival metrics for non-small cell lung cancer (NSCLC) patients, underscoring a significant gap that necessitates novel and efficacious treatment solutions. In this study, we...
Comparative Analysis of Two Digital PCR Platforms for Detecting DNA Methylation in Patient Samples [0.03%]
两种数字PCR平台在检测患者样本DNA甲基化方面的比较分析
Marek Samec,Ivana Baranova,Dana Dvorska et al.
Marek Samec et al.
The choice of appropriate analytical methods for determining methylation patterns at specific loci across the genome is essential for identifying novel diagnostic and prognostic markers for subsequent clinical implementation. Various method...
ATP-Citrate Lyase: A Prognostic Marker of Non-Small Cell Lung Cancer Dictates the Progression of Adenocarcinoma in Indian Population [0.03%]
乙酰辅酶A裂解酶：非小细胞肺癌的预后标志物，决定印度人群肺腺癌的发展进程
Kanika Phutela,Navneet Singh,Amanjit Bal et al.
Kanika Phutela et al.
Tissue biopsies are routinely used for identifying driver mutations in tumors but limitations such as tumor heterogeneity have encouraged the use of liquid biopsies for the identification of new biomarkers. ATP-citrate lyase (ACLY) has been...
RETRACTION: Chrysophanol Exhibits Inhibitory Activities Against Colorectal Cancer by Targeting Decorin [0.03%]
撤稿：番 cherry 黄素通过作用于角蛋白抑制结直肠癌
M. Deng, Y. Xue, L. Xu, et al., "Chrysophanol Exhibits Inhibitory Activities Against Colorectal Cancer by Targeting Decorin," Cell Biochemistry & Function 38, no. 1 (2020): 47-57, https://doi.org/10.1002/cbf.3445. The above article, publish...
The Role of Lactate in Mitochondrial Metabolism of DOX-Induced Senescent AC16 Cells [0.03%]
丙酮酸代谢转换诱导乳酸积聚参与心肌细胞衰老的作用及机制研究
Rosamaria Militello,Simone Luti,Tania Gamberi et al.
Rosamaria Militello et al.
Senescent cells accumulate with age in organ and tissue causing the decline of functionality and various pathological conditions including cardiovascular disease. Regular exercise induces continuous exposure to lactate that contribute to ad...
MACC1 Expression in Colorectal Cancer Is Upregulated by Loss of Epigenetic Repression Under Oxidative Stress Condition [0.03%]
氧化应激条件下表观遗传调控丢失诱导结直肠癌中MACC1表达量上升
Suchittra Phoyen,Mathias Dahlmann,Pia Herrmann et al.
Suchittra Phoyen et al.
Reactive oxygen species (ROS) cause oxidative stress and contribute to cancer genesis and progression. Metastasis-associated in colon cancer 1 (MACC1) is a key metastasis-mediating transcription factor in colorectal cancer (CRC). Whether RO...
Osteoking Ameliorates Type 2 Diabetes Osteoporosis by Enhancing Osteoblast Differentiation via PI3K/AKT/GSK-3β Pathway Activation [0.03%]
通过激活PI3K/AKT/GSK-3β信号通路增强成骨细胞分化改善2型糖尿病性 osteoking osteoporosis
Rong Li,Jiangli Lu,Peijin Wang et al.
Rong Li et al.
Osteoking (OK) exerts bone formation-promoting effects on menopausal osteoporosis and osteoporotic fractures. However, it remains to be determined whether OK ameliorates type 2 diabetic osteoporosis (T2DOP) via PI3K/AKT/GSK-3β pathway acti...
Proteomics Profiling of Early Coronary Artery Injury in a Rat Model of Type 1 Diabetes Mellitus [0.03%]
1型糖尿病大鼠冠状动脉早期损伤的蛋白质组学研究
Min Jin,Wenda Wu,Xiaomin Yang et al.
Min Jin et al.
Individuals with type 1 diabetes mellitus (T1DM) experience an increased risk of cardiovascular disease (CVD). To improve early detection and prevention strategies, a better understanding of early vascular changes is needed. Although corona...