A Review of FUN14 Domain-Containing 1 Involvement in Mitochondrial Biological Processes and Mechanisms Across Various Systems [0.03%]
FUN14结构域包含蛋白1在多系统中参与线粒体生物学过程及机制的评述
Hailun He,Xin Zhang,Lidan Xiong et al.
Hailun He et al.
FUN14 domain-containing 1 (FUNDC1), an outer mitochondrial membrane protein, has emerged as a critical regulator of mitochondrial quality control and cellular homeostasis. Initially identified as a mitophagy receptor, FUNDC1 orchestrates hy...
Gu Xiufeng,Hu Zhiping,Wang Jingzhi
Gu Xiufeng
The forkhead frame O protein (forkhead box class O proteins, FOXOs) is a highly conserved family of transcription factors, consisting of four members: FOXO 1, FOXO 3, FOXO 4, and FOXO 6. The FOXOs protein family is a ubiquitously expressed ...
DNA Methylation Alteration in Early-Stage of PSEN1/PSEN2 Gene Double Knockout Mouse Models: Integrated Bioinformatics Analysis of Hippocampal Changes Underlying Age-Related Neurodegeneration [0.03%]
PSEN1/PSEN2基因双敲除小鼠模型早期DNA甲基化改变：整合生物信息学分析海马变化以探究年龄相关神经退行性变机制
Mingxi Tang,Sibei Ruan
Mingxi Tang
Age-related neuronal loss is a critical feature of neurodegenerative disorders, including Alzheimer's disease (AD), but its underlying molecular mechanisms, particularly those involving epigenetic regulation, remain incompletely understood....
Oleuropein Ameliorates Isoproterenol-Induced Cardiac Hypertrophy Through Sirtuin-1 Activation via Endoplasmic Reticulum Stress Inhibition [0.03%]
通过内质网应激抑制激活Sirtuin-1改善橄榄苦素诱导的心肌肥厚
Hao Wang,Yang Ran,Jialin Zhong et al.
Hao Wang et al.
Cardiac hypertrophy is a major risk factor for cardiovascular disease worldwide, and Mediterranean diet has shown great benefits in reducing cardiovascular disease-related mortality and morbidity. Numerous studies have ascertained that the ...
Green Synthesis of ZnO and Mg-doped ZnO Nanoparticles Using Ferulago angulata Plant Extract and Its Effect on Second-Degree Burn Wound Healing [0.03%]
采用Ferulago angulata植物提取物绿色合成ZnO和Mg掺杂的ZnO纳米粒子及其对二度烧伤创面愈合的影响
Hori Ghaneialvar,Leila Soltani,Sajad Mami et al.
Hori Ghaneialvar et al.
In the present study, the synthesis, characterization, and therapeutic effects in treating second-degree burn wounds of the green synthesis ZnO NPs using Ferulago angulata extract and its doping with magnesium were evaluated. The prepared m...
Protection of Adipose Tissue by Pioglitazone in a Mouse Model of Doxorubicin Treatment [0.03%]
pioglitazone对DOX所致小鼠脂肪组织保护作用
Loreana Sanches Silveira,Alexandre Abilio de Souza Teixeira,Luana Amorim Biondo et al.
Loreana Sanches Silveira et al.
Cancer is a global epidemic with increasing incidence, which needs continuous efforts to enhance treatment efficacy and reduce side effects. Our study focuses on the impact of doxorubicin, a widely used chemotherapeutic agent, on white adip...
Advances in the Potential Role and Mechanism of Fibroblasts in Spinal Muscular Atrophy [0.03%]
脊髓性肌萎缩症中成纤维细胞的潜在作用和机制研究进展
Chen Chen,Jing Zhang,Chunhong Xue et al.
Chen Chen et al.
Spinal muscular atrophy (SMA) is the most common genetic disease leading to infant mortality, primarily characterized by the deficiency of survival motor neuron (SMN) protein. The effects of SMA are not limited to the nervous system but als...
Forogh Jafari,Kamalpreet Kaur,Jawairia Umar Khan et al.
Forogh Jafari et al.
The fate of mRNA in human cells is a critical aspect of gene regulation, encompassing both post-translation degradation and subcellular localization. This review explores the critical role of mRNA fate in human cells, focusing on post-trans...
Nanoparticles for Polycystic Ovary Syndrome (PCOS) Therapy: Exosomes and Synthetic Nanoparticles, Challenges and Opportunities [0.03%]
用于多囊卵巢综合征（PCOS）治疗的纳米颗粒：外泌体和合成纳米粒子，挑战与机遇
Razieh Momen Mesgin,Vahid Nejati,Shabnam Pirnezhad Talatapeh et al.
Razieh Momen Mesgin et al.
Polycystic ovary syndrome (PCOS), the most common endocrine syndrome in females, remains a human health problem worldwide. Nano-based drug delivery system has emerged as a novel therapy against PCOS. Recent developments in nanotechnology ha...
Protective Effects of Hydrothermal Extract of Crassula "Buddha's Temple" on Oxidative Stress and Lipid Metabolism in 2D and 3D Adipocyte Models [0.03%]
瓦松“瓦寺锦”热压提取物对二维和三维脂肪细胞模型中氧化应激和脂质代谢的保护作用
Eun Hye Park,Sung-Jo Kim
Eun Hye Park
Crassula "Buddha's Temple" aqueous extract (BTAE), prepared via an optimized, reproducible hydrothermal extraction, exhibits protective antioxidant and lipid regulatory effects in adipocyte models subjected to oxidative stress. The phytoche...