The mRNA-binding protein Serbp1 as an auxiliary protein associated with mammalian cytoplasmic ribosomes [0.03%]
与哺乳动物细胞质核糖体相关的mRNA结合蛋白Serbp1作为一个辅助蛋白
Akiko Muto,Yoshihiko Sugihara,Minami Shibakawa et al.
Akiko Muto et al.
While transcription plays an obviously important role in gene expression, translation has recently been emerged as a key step that defines the composition and quality of the proteome in the cell of higher eukaryotes including mammals. Selec...
Insulin-like growth factor binding protein 4 inhibits proliferation of bone marrow mesenchymal stem cells and enhances growth of neurospheres derived from the stem cells [0.03%]
胰岛素样生长因子结合蛋白4可抑制骨髓间充质干细胞的增殖并促进其向神经球分化的潜能
Huiwen Li,Shukui Yu,Fei Hao et al.
Huiwen Li et al.
Insulin-like growth factor binding protein 4 (IGFBP-4) was reported to trigger cellular senescence and reduce cell growth of bone marrow mesenchymal stem cells (BMSCs), but its contribution to neurogenic differentiation of BMSCs remains unk...
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) and liver fibrosis: A review [0.03%]
NADPH氧化酶(NOX)与肝纤维化：综述评论文章
Keywan Mortezaee
Keywan Mortezaee
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are key producer of reactive oxygen species in liver cells. Hepatic stellate cells (HSCs) and Kupffer cells (KCs) are the two key cells for expression of NOX in liver. KCs ...
Long noncoding RNA LINC00261 regulates endometrial carcinoma progression by modulating miRNA/FOXO1 expression [0.03%]
长链非编码RNA LINC00261通过调节miRNA/FOXO1表达调控子宫内膜癌进展
Qianjin Fang,Lin Sang,Shihua Du
Qianjin Fang
Long noncoding RNA LINC00261 was reported to be downregulated in multiple cancers. LINC00261 overexpression inhibits cancer cell proliferation, migration, and invasion. But the expression and function of LIN00261 in endometrial carcinoma ar...
Euxanthone inhibits glycolysis and triggers mitochondria-mediated apoptosis by targeting hexokinase 2 in epithelial ovarian cancer [0.03%]
檀香氧树脂通过作用于己糖激酶2抑制糖酵解并诱导上皮性卵巢癌细胞线粒体介导的凋亡反应
Jun Zou,Yamei Wang,Mingdi Liu et al.
Jun Zou et al.
Epithelial ovarian cancer (EOC) is one of the most prevalent gynaecological cancers. Euxanthone, an active ingredient of the medicinal plant Polygala caudata, exhibits a selective cytotoxic effect in tumour cells. The present study was aime...
Mesenchymal stem cells enhance autophagy of human intrahepatic biliary epithelial cells in vitro [0.03%]
人源肝内胆管上皮细胞的自噬作用在体外由间充质干细胞增强
Yun Zhu,Qian Wang,Xiaojun Tang et al.
Yun Zhu et al.
Dysfunctional autophagy in intrahepatic biliary epithelial cells (IBECs) is the main mechanism underlying the pathogenesis of bile duct lesions in primary biliary cholangitis. Autophagy may be a key pathogenesis for aetiology of primary bil...
NK4 inhibits the proliferation and induces apoptosis of human rheumatoid arthritis synovial cells [0.03%]
NK4对人类类风湿关节炎滑膜细胞增殖的抑制及促凋亡作用
Wenzhong Que,Huili Liu,Qinqin Yang et al.
Wenzhong Que et al.
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by proliferation and insufficient apoptosis of synovial cells. NK4 is a hepatocyte growth factor antagonist and is implicated in cell proliferation, viability, and ap...
Anti-apoptotic effects of adipose-derived adherent stromal cells in mesenchymal stem cells exposed to oxidative stress [0.03%]
氧化应激条件下间充质干细胞中脂肪组织基质细胞的抗凋亡效应
Sunhye Shin,Jung-Won Choi,Soyeon Lim et al.
Sunhye Shin et al.
Adipose-derived stromal vascular fractions (SVFs) are a heterogeneous collection of cells, and their regenerative modality has been applied in various animal experiments and clinical trials. Despite the attractive advantages of SVFs in clin...
Estrogen-related receptor alpha triggers the proliferation and migration of human non-small cell lung cancer via interleukin-6 [0.03%]
雌激素受体α通过白细胞介素-6诱导人类非小细胞肺癌的增殖和迁移
Jing Zhang,Xiangqian Guan,Naixin Liang et al.
Jing Zhang et al.
Human non-small cell lung cancer (NSCLC) is one of the leading causes of cancer deaths worldwide. Estrogenic signals have been suggested to be important for the growth and metastasis of NSCLC cells. Our present data showed that estrogen-rel...
Pristimerin targeting NF-κB pathway inhibits proliferation, migration, and invasion in esophageal squamous cell carcinoma cells [0.03%]
通过靶向NF-κB途径抑制食管鳞状细胞癌的增殖、迁移和侵袭
Yuanqing Tu,Fuxing Tan,Jingfeng Zhou et al.
Yuanqing Tu et al.
Esophageal squamous cell carcinoma (ESCC) is one of the leading causes of cancer-related death with poor prognosis in China. Identifying novel targeted therapies in ESCC is urgently needed. The aberrant activation of NF-κB signalling pathw...