hsa_circ_0058122 knockdown prevents steroid-induced osteonecrosis of the femoral head by inhibiting human umbilical vein endothelial cells apoptosis via the miR-7974/IGFBP5 axis [0.03%]
hsa_circ_0058122敲低通过miR-7974/IGFBP5轴抑制人脐静脉内皮细胞凋亡防治糖皮质激素所致股骨头坏死
Tao Yao,Lei Wang,Zhen-Fei Ding et al.
Tao Yao et al.
Background: Steroid-induced osteonecrosis of femoral head (SONFH) is a serious complication of glucocorticoid overused. Recent evidence has demonstrated that circRNAs exert key pathophysiological roles in a variety of dis...
Multicenter performance evaluation and reference range determination of a new one-stage factor VIII assay [0.03%]
一种新的FXI因子一期测定方法的多中心评估及参考区间确定研究
Anna E Lowe,Robert Jones,Steve Kitchen et al.
Anna E Lowe et al.
Introduction: We conducted a multicenter evaluation of a new one-stage factor VIII (FVIII) assay (Roche Diagnostics), intended for the quantitative assessment of FVIII activity. We evaluated the analytical performance of ...
Multicenter Study
Journal of clinical laboratory analysis. 2022 Apr;36(4):e24294. DOI:10.1002/jcla.24294 2022
Aberrant expression of long non-coding RNA PVT1 in allergic rhinitis children: Correlation with disease risk, symptoms, and Th1/Th2 imbalance [0.03%]
过敏性鼻炎儿童长链非编码RNA PVT1异常表达及其与疾病风险、症状和T淋巴细胞1型/2型失衡的相关性研究
Yujun Sun,Jingjing Han,Haifeng Ma et al.
Yujun Sun et al.
Background: Long non-coding RNA plasmacytoma variant translocation 1 (lnc-PVT1) exacerbates inflammation and induces T helper (Th) 1/Th2 imbalance in allergic diseases, but its clinical role in allergic rhinitis (AR) rema...
The application of certified reference materials for clinical mass spectrometry [0.03%]
临床质谱分析中认证参考物质的应用
Shen Lingxiao,Ma Jinfei,Yang Qingqing et al.
Shen Lingxiao et al.
Background: In the application process of clinical mass spectrometry, there are difficulties such as standardization, low degree of automation, complex instruments, and high requirements for operations, which will affect ...
Alinity hq platelet count is not impacted by severe microcytosis [0.03%]
Alinity hq血小板计数不受严重小细胞低色素性贫血的影响
Gabriella Lakos,Zainab Mukhtar,Loredana Masi et al.
Gabriella Lakos et al.
Background: Impedance technology has been shown to overestimate platelet (PLT) count in samples with microcytes, while the optical-fluorescence PLT count (PLT-F) by Sysmex has been suggested to be unaffected by microcytos...
Possible effects of Treponema pallidum infection on human vascular endothelial cells [0.03%]
苍白密螺旋体感染对人血管内皮细胞的可能影响
Bibo Xie,Tie Zhao,Sisi Zhao et al.
Bibo Xie et al.
Pathogens can affect host cells in various ways, and the same effect can be found in the Treponema pallidum acting on the endothelium of host vessels, and the mechanism is often complex and multiple. Based on the existing T. pallidum of a c...
Jianli Zhang,Jing Yang,Jingchun Hu et al.
Jianli Zhang et al.
Background: Jun N-terminal kinase pathway-associated phosphatase (JKAP) regulates neuronal function, T helper (Th) 1/2/17 cell differentiation, and inflammatory process, but its clinical role in acute ischemic stroke (AIS...
Evaluation of a cardiac troponin process flow at the chest pain center with the shortest turnaround time [0.03%]
于胸痛中心采用周转时间最短的流程检测心肌损伤标志物高敏感性心脏型肌钙蛋白指标评价研究
Hao Wang,Xinyue Wang,Kouqiong Wang et al.
Hao Wang et al.
Background: Early diagnosis of myocardial infarction is crucial in chest pain management and cardiac troponin (cTn) test is an important step in it. Process improvement to shorten the test turnaround time (TAT) may improv...
Aberrant blood MALT1 and its relevance with multiple organic dysfunctions, T helper cells, inflammation, and mortality risk of sepsis patients [0.03%]
异常血MALT1及其与多器官功能障碍、T辅助细胞、炎症和脓毒症患者死亡风险的相关性
Yibin Wang,Qinghe Huang,Fuyun He
Yibin Wang
Background: MALT1 is linked with multiple organic dysfunctions, inflammatory storm, and T helper (Th) cell differentiation. Herein, the current study aimed to investigate the correlation of peripheral blood mononuclear ce...
E2F4 may be a core transcription factor in the lncRNA-TF regulatory network in cervical cancer [0.03%]
E2F4可能是宫颈癌长链非编码RNA-转录因子调控网络的核心转录因子
Haiyan Yang,Xiaoli Qu,Jiangang Huang et al.
Haiyan Yang et al.
Background: Cervical cancer is the most common gynecological cancer worldwide and is associated with high morbidity and mortality. Despite improvements in therapeutic strategies, the network regulation mechanism remains u...