LncRNA TUG1 functions as a ceRNA for miR-1-3p to promote cell proliferation in hepatic carcinogenesis [0.03%]
长链非编码 RNA TUG1 通过作用于 miR-1-3p 的 ceRNA 促进肝细胞增殖及致癌性
Keke Tang,Di Lv,Lingling Miao et al.
Keke Tang et al.
Background: Hepatocellular carcinoma (HCC) is characterised by high malignancy, metastasis and recurrence, but the specific mechanism that drives these outcomes is unclear. Recent studies have shown that long noncoding RN...
Circulating cell-free circRNA panel predicted tumorigenesis and development of colorectal cancer [0.03%]
循环细胞游离circRNA谱预测结直肠癌的发生及发展过程
Le Qi,Ying Pan,Min Tang et al.
Le Qi et al.
Background: Colorectal cancer (CRC) is reported with high morbidity and mortality. Currently, the sensitivity of diagnostic markers for colorectal cancer is low. Therefore, further exploration of new plasma diagnostic mar...
Blocking PARP activity with the inhibitor veliparib enhances radiotherapy sensitivity in endometrial carcinoma [0.03%]
PARP抑制剂Veliparib能增强子宫内膜癌的放疗敏感性
Jing Wang,Weizhen Xing,Yanling Lin et al.
Jing Wang et al.
Objective: Our study aimed to investigate the potential clinical utility of a poly(ADP-ribose) polymerase (PARP) inhibitor, veliparib (ABT-888), as a radiosensitizer in the medication of endometrial carcinoma (EC). ...
Identification of autophagy-related biomarker and analysis of immune infiltrates in oral carcinoma [0.03%]
口腔癌自噬相关生物标志物的识别及免疫浸润分析
Honghai Fu,Dianguo Zhao,Legang Sun et al.
Honghai Fu et al.
Background: Autophagy plays a vital role in the progression of the tumor. We aimed to investigate the expression, prognostic value, and immune infiltration of autophagy-related genes in oral carcinoma via bioinformatics a...
Identification and construction of a 13-gene risk model for prognosis prediction in hepatocellular carcinoma patients [0.03%]
基于13个基因的肝癌预后风险预测模型的构建与验证
Daming Cheng,Libing Wang,Fengzhi Qu et al.
Daming Cheng et al.
We attempted to screen out the feature genes associated with the prognosis of hepatocellular carcinoma (HCC) patients through bioinformatics methods, to generate a risk model to predict the survival rate of patients. Gene expression informa...
Constructing an immune- and ferroptosis-related lncRNA signature to predict the immune landscape of human bladder cancer [0.03%]
构建与免疫和铁死亡相关的长链非编码RNA标志物以预测人类膀胱癌的免疫图谱
Xing Li,Libin Zhou,Tefei Lu et al.
Xing Li et al.
Background: LncRNAs play a variety of roles in the tumor microenvironment and cancer immune responses. Determining the significance of bladder cancer (BLCA)-related genes to predict the prognostic and therapeutic response...
Saeed Khoshnood,Maniya Arshadi,Sousan Akrami et al.
Saeed Khoshnood et al.
After about 2 years since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first infections were detected in Wuhan city of China in December 2019, which was followed by a worldwide pandemic with a record of 5.41 million deaths....
LINC00240 knockdown inhibits nasopharyngeal carcinoma progress by targeting miR-26a-5p [0.03%]
LINC00240敲低通过靶向miR-26a-5p抑制鼻咽癌的发展
Xing Chen,Guixiang Wu,Jing Qing et al.
Xing Chen et al.
Objective: This study intended to explore the regulatory functions of LINC00240 on nasopharyngeal carcinoma (NPC). Methods: MiR-26a-5p ...
DNA testing for sickle cell anemia in Africa: Implementation choices for the Democratic Republic of Congo [0.03%]
非洲的镰状细胞贫血症DNA检测：刚果民主共和国的实施选择
Mamy Ngole,Valerie Race,Gloire Mbayabo et al.
Mamy Ngole et al.
Background: Hemoglobin-based tests form the reference diagnostic test for SCA. In limited resource countries, these tests face limitations including cost, low sensitivity due to recurrent transfusions in endemic malaria r...
The value of neutrophil-to-lymphocyte ratio combined with the thyroid imaging reporting and data system in the diagnosis of the nature of thyroid nodules [0.03%]
中性粒细胞与淋巴细胞比率联合甲状腺影像报告和数据系统在判断结节性质中的价值
Jie Zhang,Zhaoxia Gong,Shanshan Li et al.
Jie Zhang et al.
Objective: The aim of this study was to investigate the diagnostic value of peripheral blood neutrophil-to-lymphocyte ratio (NLR) combined with the thyroid imaging reporting and data system (TIRADS) for benign and maligna...