Delivery Routes and Anesthesia Affect Cord Blood NGF, BDNF, and Neonatal Outcomes [0.03%]
分娩方式和麻醉方式影响胎盘血NGF、BDNF含量及新生儿结局
Şükran Doğru,Huriye Ezveci,Fikriye Karanfil Yaman et al.
Şükran Doğru et al.
Objective: This study aimed to investigate the effects of delivery mode and anesthesia type on fetal cord blood levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), which are neurotrophins inv...
Resolving a Complex Neonatal Phenotype by Rapid Trio Whole-Genome Sequencing: A De Novo 11q14.3-q22.3 Deletion and a Splicing-Altering Synonymous ANK1 Variant [0.03%]
通过快速三联体全基因组测序解析复杂的新生儿表型：一种自闭症的11q14.3-q22.3新发缺失和ANK1同义变异剪接改变变异
Hyun-Woo Lee,Ja-Hyun Jang,Beom Hee Lee et al.
Hyun-Woo Lee et al.
Background: Neonates with complex and evolving phenotypes often lack sufficiently specific clinical features to guide targeted genetic testing. Rapid trio whole-genome sequencing (WGS) may provide comprehensive etiologic ...
Plasma Very-Long-Chain Fatty Acids in X-Linked Adrenoleukodystrophy: Diagnostic Insights From a Clinical Laboratory Cohort [0.03%]
X染色体连锁肾上腺脑白质营养不良的血浆极长链脂肪酸：来自临床实验室队列的诊断见解
Sergio Molina Blas,Sergio Pérez Pujalte,Ana Moreno Álvarez et al.
Sergio Molina Blas et al.
Background: X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder caused by pathogenic variants in the ABCD1 gene, leading to accumulation of very long-chain fatty acids (VLCFAs). Plasma VLCFA measurement is cen...
Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants [0.03%]
一种新型抗凝血酶检测法的初步评估结果显示其不受抗凝剂影响
Ayu Hidaka,Risa Kaneshige,Seika Nakamura et al.
Ayu Hidaka et al.
Background: In Japan, clinical laboratories commonly assess lupus anticoagulant (LA) activity using phospholipid-dependent coagulation assays as part of the diagnostic evaluation of antiphospholipid syndrome (APS). Howeve...
Improving Linkage to the HCV Care Cascade in Nonspecialist Settings: Evaluation of the Performance and Triage Utility of the Elecsys HCV Duo Assay in Japan [0.03%]
在日本非专科医疗机构中改进丙肝诊疗流程：Elecsys丙肝二联检测试剂的性能及分诊效用评估
Hiroko Setoyama,Takehisa Watanabe,Shiho Miyase et al.
Hiroko Setoyama et al.
Background: In Japan, the hepatitis C virus (HCV) care cascade is constrained at the transition from anti-HCV antibody screening to confirmatory HCV ribonucleic acid (HCV RNA) testing in nonspecialist departments. As HCV ...
Xintong Xu,Zining Wang,Jiaming Hu et al.
Xintong Xu et al.
Background: Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. The disease is de...
Extreme Heterophilic Antibody Interference in BNP Immunoassay: A Case Report and Systematic Investigation Protocol [0.03%]
极端异磷酯抗体干扰BNP免疫测定的病例报告和系统调查方案
Huicong Yang,Yuanhai Zheng,Zhenhua Zeng et al.
Huicong Yang et al.
Background: Heterophilic antibody (HA) interference remains a persistent challenge in immunoassay diagnostics. Human anti-mouse antibodies (HAMA) can cause spuriously elevated biomarker results, potentially leading to mis...
Pseudohyperphosphatemia in Multiple Myeloma: A Systematic Review of Case Reports and Case Series [0.03%]
浆细胞瘤合并假高磷血症的病例报道和案例系列的系统性回顾
Mahsa Dabir,Maryam Kamrani Mousavi,Mohana Mohamadi et al.
Mahsa Dabir et al.
Background: Pseudohyperphosphatemia (PHP) is a laboratory artifact that may occur in patients with multiple myeloma (MM) due to interference from circulating paraproteins in colorimetric phosphate assays. Misinterpretatio...
Not Missing the Notch: Detection Challenges of Juxtamembrane NOTCH1 Variant Detection in T-Cell Acute Lymphoblastic Leukemia [0.03%]
不要忽视NOTCH1位点突变的检测难度——T细胞急性淋巴细胞白血病中近膜NOTCH1变异体的检测挑战
Francisco Beas,Stephan Hutter,Ferran Balbastre-Úbeda et al.
Francisco Beas et al.
Background: Activating mutations in NOTCH1 are frequent in T-cell acute lymphoblastic leukemia (T-ALL) and, in the absence of alterations in RAS or PTEN, are associated with favorable prognosis. Besides classical heterodi...
Utility of a Combined Diagnostic and Severity Scoring System Based on Complete Blood Count and Derived Immune-Inflammatory Indicators in Children With Mycoplasma pneumoniae Pneumonia [0.03%]
基于血液常规检测指标和衍生免疫炎症标志物的支原体肺炎诊断与病情严重程度评估模型的临床价值研究
Quan Liu,Li Wei,Liang Wang et al.
Quan Liu et al.
Background: This study assessed the diagnostic value of complete blood count (CBC) and derived immune-inflammatory indicators for Mycoplasma pneumoniae pneumonia (MPP) in children and developed a practical scoring system ...