Investigation of Specific IgG-Secreting Cells in Congenital Toxoplasmosis: The TOXODIAG Study [0.03%]
先天性弓形虫病特异性IgG分泌细胞的检测：TOXODIAG研究
F Migot-Nabias,N Beldjoudi,K Bailly et al.
F Migot-Nabias et al.
Background: Current neonatal diagnostic tests for congenital toxoplasmosis (CT) have limited performance, which is particularly problematic in resource-limited settings and where monitoring for toxoplasmosis during pregna...
Development and Analytical Validation of a Laboratory-Customized TaqMan-MGB Probe Method for CYP2C19 Genotyping [0.03%]
一种用于CYP2C19基因分型的实验室定制TaqMan-MGB探针方法的建立及分析验证
Yaqun Liu,Lianghui Chen,Xuanyi Zheng et al.
Yaqun Liu et al.
Background: Genetic polymorphisms in CYP2C19 influence the metabolism of multiple clinically important drugs. Although TaqMan-based genotyping of CYP2C19*2 and CYP2C19*17 is well established, open and locally implementabl...
Heavy Metal Mixture Exposure and Insulin Resistance in U.S. Adults: The Mediating Role of Systemic Inflammation [0.03%]
美国成年人的重金属混合暴露与胰岛素抵抗：全身性炎症的介导作用
Cai Zhang,Shidi Lin,Yu Lin
Cai Zhang
Introduction: Exposure to heavy metals has been implicated in insulin resistance (IR), yet the mechanisms remain unclear. Systemic inflammation may link metal exposure to metabolic outcomes. ...
A New Diagnostic Approach Using the NLR/LMR Ratio in the Differential Diagnosis of Neck Masses: Hematologic Evaluation of Patients With Cervical Lymphadenopathy [0.03%]
一种新的诊断方法：利用NLR/LMR比值对颈部肿块进行鉴别诊断及其血液学评估
Servet Erdemes,Gizem Ay Haldız,Müslüm Ayral et al.
Servet Erdemes et al.
Objective: To evaluate the diagnostic utility of hematologic ratios derived from routine complete blood count parameters in differentiating malignant, granulomatous, and reactive cervical lymphadenopathies, with a particu...
Elevated Hemoglobin A2: A Molecular Revisited, and Implications to β-Thalassemia Screening [0.03%]
血红蛋白A2升高：分子机制回顾及其在β-地中海贫血筛查中的意义
Kritsada Singha,Anupong Pansuwan,Hataichanok Srivorakun et al.
Kritsada Singha et al.
Background: In Thailand, the Hb A2 cut-off value for β-thalassemia carrier has been changed from 4.0% to 3.6% since 2015. We examined the molecular basis of β-thalassemia in a large cohort of Thai subjects with this cha...
Soluble B7-H6 as a Novel Diagnostic Biomarker for Post-Hepatitis B Cirrhosis: A Clinical Value Study [0.03%]
可溶性B7-H6作为诊断乙肝肝硬化的新型生物标志物的临床价值研究
Kaiyong Chen,Luxuan Yang,Huaiwu Fu et al.
Kaiyong Chen et al.
Objective: This study aimed to assess the diagnostic value of soluble B7-H6 (sB7-H6) as a biomarker for post-hepatitis B cirrhosis (LC) and to compare its performance with conventional non-invasive biomarkers, including F...
First Report of Co-Inheritance of Hemoglobin British Columbia (HBB:c.304G>A) and β-Thalassemia IVS-I-6 (HBB:c.92+6T>C): Clinical Characterization of an Iranian Case [0.03%]
伯克姆海滩血红蛋白(HBB:c.304G>A)和β-地中海贫血IVS-I-6(HBB:c.92+6T>C)共病的首例报告：一例伊朗病例的临床特征描述
Kimia Fathalizade,Mahsa Kiani Bigdeli,Seyed Sajad Eghbali et al.
Kimia Fathalizade et al.
Background: Hemoglobin British Columbia is a rare high-oxygen-affinity β-globin variant caused by the HBB:c.304G>A substitution. Its detection is exceptionally uncommon, particularly in the Middle East, and may lead to d...
Reference Interval Establishment for Four Coagulation Parameters Using Indirect Methods in a High-Altitude Chinese Population: A Retrospective Real-World Analysis [0.03%]
高海拔地区四种凝血参数参考区间的建立：回顾性真实世界分析
Banjiu Zhaxi,Danni Mu,Shengfang Ye et al.
Banjiu Zhaxi et al.
Objectives: This study utilized two indirect methods to establish reference intervals (RIs) for four coagulation parameters for the adult population in Tibet, a high-altitude region in Western China. ...
Biomarkers of Endothelial Damage in Acute Graft-Versus-Host Disease After Allogenic Hematopoietic Stem Cell Transplantation: Methodological Challenges [0.03%]
异基因造血干细胞移植后急性移植物抗宿主病内皮损伤生物标志物的测定：方法学挑战
Katarina Klinar,Helena Podgornik
Katarina Klinar
Background: Acute graft-versus-host disease (aGVHD) is a major complication following allogeneic hematopoietic stem cell transplantation. The current diagnostic approach relies primarily on clinical manifestations and his...
Serum Apelin-13 and Galectin-3 in COVID-19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case-Control Study [0.03%]
COVID-19患者血清中APN-13和LGALS3的表达及其与生化指标相关性的病例对照研究分析
İsmail Uğurlu
İsmail Uğurlu
Background: Apelin-13 and Galectin-3 (Gal-3) are bioactive mediators linked to inflammation and cardiometabolic pathways. Their clinical utility in COVID-19 alongside routine laboratory tests remains unclear. ...