The Immunoregulatory and Hematopoietic Effects of Momelotinib in a Murine Bone Marrow Failure Model [0.03%]
莫莫替尼在小鼠骨髓衰竭模型中的免疫调节和造血作用
Yue Zhang,Huiqin Zhang,Naibo Hu et al.
Yue Zhang et al.
Background: Immune-mediated bone marrow failure (AA) is characterized by T cell-mediated destruction of hematopoietic stem and progenitor cells (HSPCs). The JAK-STAT signaling pathway plays a crucial role in regulating im...
Integrating Clinical Features, Laboratory Biomarkers and Computed Tomography for the Discrimination of Non-Small Cell Lung Cancer and Benign Pulmonary Diseases: A Clinical Prediction Model [0.03%]
临床特征、实验室生物标志物和CT影像鉴别肺癌与肺良性病变的列线图模型研究
Jie Zhang,Shui Liu,Mingjian Bai et al.
Jie Zhang et al.
Objective: To develop and validate a clinical prediction model for differentiating non-small cell lung cancer (NSCLC) from benign pulmonary diseases (BPD). ...
Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours [0.03%]
基于RNA融合 panel 的小核酸变异分析（SMURF）：充分利用实体瘤中的 RNA 测序数据
Pranav Dorwal,Julie Robin,Broden Krause et al.
Pranav Dorwal et al.
Background: RNA-based fusion panels using targeted next-generation sequencing of formalin-fixed paraffin-embedded tumour tissue specimens are used for various tumour types to detect rearrangements/fusions. Using bioinform...
Reference Intervals for Lymphocyte Subpopulations in Healthy Chinese Han Adults: A Single-Center Study [0.03%]
中国汉族健康成年人淋巴细胞亚群参考区间的一项单中心研究
An-Na Jiang,Lin-Zi Miao,Yan Gong et al.
An-Na Jiang et al.
Objectives: To establish reference intervals of lymphocyte subpopulations in the healthy Chinese Han adult population and to explore the relationship between the lymphocyte subpopulations and routine health indicators. ...
Remarkable Prolongation of Irreversible APTT and Non-Significant Hemorrhage: A Rare High Titer of FVIII Inhibitor Case Report and Literature Review [0.03%]
凝血酶时间不可逆延长而无明显出血的罕见八因子高滴度抑制物病例报道及文献复习
Ke-Han Zhang,Song-Song Lu,Pei-Liang Gao et al.
Ke-Han Zhang et al.
Background: Acquired hemophilia A (AHA) is a rare hemorrhagic disease characterized by isolated prolongation of activated partial thromboplastin time (aPTT) and existence of autoantibodies against factor VIII (FVIII). ...
Clinical and Genetic Significance of Chromosomal Microarray Screening of Asymptomatic Newborns [0.03%]
无症状新生儿染色体微阵列检测的临床和基因意义
Naye Choi,Hwa Young Kim,Jung Min Ko
Naye Choi
Introduction: In South Korea, low-resolution chromosomal microarray analysis (LR-CMA) is frequently used as a screening tool to identify chromosomal anomalies in asymptomatic newborns. However, its clinical utility remain...
Veronica Buia,Martina Bonacini,Cecilia Catellani et al.
Veronica Buia et al.
Background: Soluble immune checkpoints (sICs) are emerging as possible serum and plasma biomarkers in cancer and immune-mediated diseases, but little is known about the impact of the matrix type in sIC detection. This stu...
The Application Value of Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing in Moderate-to-Severe Bronchiectasis [0.03%]
支扩症患者肺泡灌洗液宏基因组测序的临床应用价值研究
Jiachun Li,Qiuping Quan,Junshan Chen et al.
Jiachun Li et al.
Background: Bronchiectasis, a leading chronic airway disease, often worsens due to infections, making rapid pathogen detection crucial. This study aims to evaluate the diagnostic value of bronchoalveolar lavage fluid (BAL...
Analytical Comparison of Three Commercial Lysing Reagents for Full-Spectrum Flow Cytometric Immunophenotyping [0.03%]
三种商品化裂解试剂的分析比较及全光谱流式免疫分型检测方法评价研究
Elizabeth Huamanyalli-Villar,Julia Moya-Naranjo,Billy Sanchez-Jacinto et al.
Elizabeth Huamanyalli-Villar et al.
Introduction: Flow cytometry (FC) enables rapid identification of cell lineages based on their fluorescent and light-scattering properties, playing a critical role in diagnosing and monitoring oncohematological diseases. ...