Plasma Proteomic Profiling Identifies Candidate Biomarkers for Pancreatic Ductal Adenocarcinoma [0.03%]
血浆蛋白质组分析鉴定出胰腺导管腺癌的候选生物标志物
Lelang Xiang,Yi Jin,Ran Hu et al.
Lelang Xiang et al.
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy that is often diagnosed after curative treatment is no longer feasible. Existing biomarkers, particularly CA19-9, have limited sensitivity ...
Diagnostic Performance of Direct PCR Assay for Candida auris Detection: A Comparison of Liquid Amies Transport Medium and Fungal Enrichment Broth [0.03%]
采用直接PCR检测耳念珠菌的方法学性能评估：爱德华氏采集管和真菌增菌液的对比研究
Jung-Ah Kim,Yu Kyung Jeon,Eun Jeong Won et al.
Jung-Ah Kim et al.
Background: Candida auris has rapidly spread worldwide, representing a significant global health threat. Rapid diagnostic testing is essential for C. auris infection control. This study aimed to assess the diagnostic perf...
A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies [0.03%]
人肠道微生物组与血液系统恶性肿瘤和非恶性疾病之间双向互作的全面研究：聚焦新型治疗策略
Alireza Molajafari,Hadi Sedigh Ebrahim-Saraie,Majid Taati Moghadam et al.
Alireza Molajafari et al.
Background: The human microbiota plays a key role in maintaining host homeostasis by regulating immune responses, metabolism, and hematopoiesis. Microbial dysbiosis has been increasingly associated with immune dysfunction...
Organ-Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies [0.03%]
器官特异性的人类微生物组与菌群失调：与疾病及新兴治疗策略的机制联系
Awadh Alanazi
Awadh Alanazi
Background: The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness. Dysbiosis, or disruption of this delicately regulated microbial ecology, ...
Measurement of Plasma Free Hemoglobin Using the Hemolysis Index of the Mindray BS-800 [0.03%]
迈瑞BS-800溶血指数测定血浆游离血红蛋白水平的方法学评估
Punchisa Viruttanachai,Nuttiruetai Chanpo,Anchalee Thedsawad et al.
Punchisa Viruttanachai et al.
Background: The Mindray BS-800 chemistry analyzer (Mindray Bio-Medical Electronics) has a hemolysis index (HI) function and is a candidate method for detecting free hemoglobin (fHb). This study aimed to validate the HI on...
IGFBP3 As a Potential Biomarker and Therapeutic Target in Hepatocellular Carcinoma: A Multi-Cohort Analysis [0.03%]
肝细胞癌中IGFBP3的潜在生物标志物和治疗靶点作用：多队列分析
Yin Tao,Yunji Xu,Xupeng Chen et al.
Yin Tao et al.
Objective: This study aimed to investigate the expression patterns and prognostic significance of insulin-like growth factor-binding protein 3 (IGFBP3) in hepatocellular carcinoma (HCC) and other cancer types. ...
Optimization of Reflex Testing Rules on the Sysmex XN-9100 Automated Hematology Line Improves Efficiency and Reduces Repeat Testing in Different Work Areas [0.03%]
优化Sysmex XN-9100全自动血液细胞分析流水线的复查规则提高效率及降低复检率
Lianhui Yu,Min Zhang,Jianying Li et al.
Lianhui Yu et al.
Introduction: With the widespread implementation of automated hematology systems, Reflex testing plays a critical role in result verification. However, overly sensitive Reflex rules may lead to excessive repeat testing, i...
sFlt-1/PlGF Ratio in the Diagnosis of Preeclampsia on the MAGLUMI X3 Analyzer [0.03%]
MAGLUMI X3化学发光免疫分析仪检测胎盘生长因子/placenta growth factor检测诊断子痫前期的价值研究
Pavel Broz,Simona Kukralova,Zdenek Sebesta et al.
Pavel Broz et al.
We compared the analytical and clinical performance of MAGLUMI X3 (Snibe) and Elecsys (Roche) for measuring sFlt-1, PlGF, and their ratio in women hospitalized at the Department of Gynecology and Obstetrics, University Hospital in Pilsen. I...
Application of Cell-Free DNA Barcode-Enabled Single-Molecule Test for Non-Invasive Prenatal Testing of α-Thalassemia and β-Thalassemia [0.03%]
基于游离DNA条形码的单分子检测技术在无创产前检查地中海贫血中的应用研究
Qin Liu,Na Ma,Wanglan Tang et al.
Qin Liu et al.
Purpose: To assess the feasibility of using the cell-free DNA barcode-enabled single-molecule test (cfBEST) for non-invasive prenatal testing (NIPT) of α-thalassemia and β-thalassemia. ...
Changes of CEA Diagnostic Performance Under the New Reference Interval Stratified by Age and Sex [0.03%]
基于性别和年龄分层的新参考区间下CEA诊断性能的变化
Ke Zhang,Xiarui Ye
Ke Zhang
Background: CEA is one of the most frequently used biomarkers for cancer, but its inappropriate reference interval, low sensitivity, and specificity limit its clinical application. ...