Development and Validation of In-House Conventional and Multiplex PCR Methods for the Detection and Identification of Lophomonas spp.: An Innovative Approach [0.03%]
里菲阿米巴属鞭毛虫检测和鉴定的实验室方法建立及验证：一种创新的方法学研究
Maryam Nakhaei,Mahdi Fakhar,Abouzar Bagheri et al.
Maryam Nakhaei et al.
Background: Pulmonary lophomoniasis is an emerging disease caused by the protozoan pathogen Lophomonas spp. Recently, a conventional polymerase chain reaction (PCR) method has been developed. However, its sensitivity and ...
Fluctuations and Changes in Acute Phase Reactive Proteins in Fasting and Nonfasting States [0.03%]
禁食与非禁食状态下急性时相反应蛋白的波动及变化
Ben Huang,Shuxian Miao,Yan Xu et al.
Ben Huang et al.
Background: In clinical practice, acute-phase reactive proteins (APRPs) are frequently measured at random times. However, it is unclear whether the use of fasting or nonfasting samples affects results. This study aims to ...
Macrophage and Preeclampsia: Macrophage Polarization Imbalance at the Maternal-Fetal Interface [0.03%]
巨噬细胞与子痫前期：母胎界面巨噬细胞极化失衡
Yao Wei,Yang Su,Cheng Liu et al.
Yao Wei et al.
Background: Preeclampsia (PE), as a pathological pregnancy process, is still unclear in its precise pathophysiology. The current consensus on PE pathogenesis is that it is an immune-inflammatory response due to placental ...
Prenatal Diagnosis and Clinical Phenotypic Heterogeneity of 22q11.2 Microdeletion Syndrome Based on a Single Center Retrospective Study [0.03%]
基于单中心回顾性研究的22q11.2微缺失综合征的产前诊断及临床表型异质性分析
Jia-Yan Chen,Mei-Jiao Cai,Yun-Sheng Ge
Jia-Yan Chen
Objective: To retrospectively investigate the incidence of prenatal diagnosis of 22q11.2 microdeletion syndrome (22q11.2DS) in a single center and summarize its clinical manifestations to expand the phenotypic database. ...
Novel Biomarkers for Improving the Diagnosis of Appendicitis in Pediatric Patients [0.03%]
改善儿科患者阑尾炎诊断的新生物标志物
Adir Alper,Yizhak Aronov,Lior Shlomov et al.
Adir Alper et al.
Introduction: Diagnosing appendicitis in pediatric patients remains a clinical challenge, especially in resource-limited settings where imaging tools are less accessible. Inflammatory markers, including the Neutrophil-to-...
Endurance Training Alleviates Metabolic-Associated Fatty-Liver Disease (MAFLD)-Related Testicular Impairments via Endoplasmic Reticulum Stress Regulation [0.03%]
耐力训练通过调节内质网应激缓解与代谢相关脂肪性肝病(MAFLD)相关的睾丸损伤
Nastaran Teimouri,Vahid Kazemizadeh
Nastaran Teimouri
Background: Metabolic-associated fatty liver disease (MAFLD), the most prevalent liver disorder globally, affects 20%-40% of the population and presents significant health challenges. Studies link MAFLD to male reproducti...
Levels of IL-1β, MMP-8, and MMP-9 in the Saliva of Subjects With Periodontitis: A Systematic Review and Meta-Analysis [0.03%]
牙周病患者唾液中IL-1β、MMP-8和MMP-9水平的系统评价和 meta 分析
Mario Alberto Alarcón-Sánchez,Ruth Rodríguez-Montaño,Seyed Ali Mosaddad et al.
Mario Alberto Alarcón-Sánchez et al.
Background and objective: Proinflammatory cytokines and enzymes responsible for tissue destruction are important in the development of periodontitis. This study compared salivary concentrations of interleukin-1 beta (IL-1...
Development of a Multiplexed qPCR Kit for the Detection of Bloodstream Infection [0.03%]
多重定量血液感染检测试剂盒的开发
Kai Niu,Yiping Wang,Zhiyu Pang et al.
Kai Niu et al.
Background: Bloodstream infection (BSI) is associated with high morbidity and mortality worldwide. Currently, BSI diagnosis relies on a time-consuming blood culture method, which usually takes 2 or more days to identify t...
Phenotype Detection and Drug Resistance Analysis of Carbapenem-Resistant Gram-Negative Bacilli [0.03%]
碳青霉烯耐药革兰阴性杆菌的表型检测及耐药分析
Xiao-Min Liu,Ya-Xian Wu,Xiao-Hui Li et al.
Xiao-Min Liu et al.
Background: The increasing prevalence of infections caused by carbapenem-resistant organisms (CRO) represents a global health issue. Therefore, a rapid and accurate method for detecting these microbes in any clinical micr...
Assessment of Healthcare Professionals' Knowledge Regarding Nontuberculosis Mycobacterial Infections at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2024: A Cross-Sectional Study [0.03%]
2024年埃塞俄比亚西北部德布雷塔沃尔综合专科医院医务人员非结核分枝杆菌感染知识评估：一项横断面研究
Teklehaimanot Kiros,Mulat Erkihun,Bekele Sharew et al.
Teklehaimanot Kiros et al.
Background: Nontuberculosis mycobacteria (NTM) are environmental pathogens that can cause pulmonary infections, especially among the immunocompromised population. There is limited research on healthcare professionals' kno...