Experimental Validation of an Immune Cell Infiltration Signature in Psoriasis: Translating Computational Modeling to In Vivo Efficacy [0.03%]
银屑病免疫细胞浸润特征的实验验证:从计算模型到体内疗效的转化研究
Tingjin Zheng,Rong Xu,Jianming Zhang et al.
Tingjin Zheng et al.
Objective: The psoriatic immune microenvironment (PIME) is central to psoriasis pathogenesis, yet its mechanistic drivers are incompletely defined. This study aimed to delineate immune cell infiltration patterns and ident...
Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review [0.03%]
轻链不协同的重链病的新实验室方法:病例报告和文献回顾
Eleonora Longhi,Artan Çeka,Fabiola Olivieri et al.
Eleonora Longhi et al.
Background: Heavy chain disease (HCD) is a rare plasma-cell neoplasm frequently linked to lymphoproliferative and autoimmune disorders. Clinical presentation varies widely, with no conventional signs or symptoms. The prog...
The Application Value of Flow Cytometry-Based Peripheral Blood Leukocyte Classification in Screening for Acute Leukemia and Posttreatment Monitoring [0.03%]
基于流式细胞仪的外周血白细胞分类技术在急性 leukemia筛查和疗效监测中的应用价值研究
Penghua Yan,Lianfeng Wu,Xiangyang Lin et al.
Penghua Yan et al.
Objective: Assess the application value of flow cytometry (FCM) for peripheral blood leukocyte (PBL) classification in acute leukemia (AL) screening and monitoring. ...
Indirubin and Retinoic Acid Show Binding Affinity to Monocyte Biomarker CSF3R in Parkinson's Disease [0.03%]
吲哚玉和视黄酸对帕金森病单核细胞生物标志物CSF3R的亲和力结合作用研究
Zhiwei Bao,Shao Zhi,Mao Jie
Zhiwei Bao
Background: This study integrated multi-omics data analysis to elucidate key molecular alterations associated with monocytes in Parkinson's disease (PD) so as to identify novel biomarkers. ...
Antibacterial Activity of Fresh and Autoclaved Platelet-Rich Fibrin on Pseudomonas aeruginosa: An In Vitro Study [0.03%]
新鲜和高压灭菌富血小板纤维蛋白对铜绿假单胞菌抗菌活性的体外研究
Ahmed I Alzahrani,Shaban R M Sayed,Yasser F Alrayyes et al.
Ahmed I Alzahrani et al.
Objective: Platelet-rich fibrin (PRF) is widely used in oral and maxillofacial procedures for its regenerative and antimicrobial properties. Structural modifications, such as autoclaving, may enhance its usability. This s...
The Ability of Serum Amyloid A to Discriminate Coronavirus Disease 2019 (COVID-19) Patients Who Stay Moderately Ill Versus Patients Who Become Severely Ill [0.03%]
血清淀粉样蛋白A鉴别新冠病毒疾病(COVID-19)患者持续中症与恶化重症的能力
Nadine M C Pouw,Tessa Noordermeer,Bianca Boxma-de Klerk et al.
Nadine M C Pouw et al.
Background: As the disease course of coronavirus disease 2019 (COVID-19) can change rapidly, clinically relevant prognostic biomarkers could facilitate clinical-decision making. Prior research has shown that Serum Amyloid...
Impact of COVID-19 Pandemic on Antibiotic Resistance Patterns of Common Bacterial Pathogens to Antibiotics in Northern Ghana [0.03%]
2019冠状病毒病大流行对北加纳常见细菌耐药模式的影响研究
Hisham Alhassan Osumanu,Oliver Nangkuu Deberu,Abass Abdul-Karim et al.
Hisham Alhassan Osumanu et al.
Background: Before the COVID-19 pandemic, Northern Ghana reported high resistance to third-generation cephalosporins, but most bacteria remained susceptible to amikacin and meropenem. Increased antimicrobial use during th...
Prolonged Turnaround Time of the Hematology Laboratory and Related Factors in the South Gondar Zone, North West Ethiopia, Multi-Centered Study [0.03%]
延长的血液学实验室周转时间及其相关因素:尼日利亚西北部高登拉区多中心研究
Birhanemaskal Malkamu,Getaneh Atikilt Yemata,Andargachew Almaw et al.
Birhanemaskal Malkamu et al.
Background: Turnaround time refers to the time it takes from receiving a sample in the lab to delivering test results to clinicians or stakeholders. This study aimed to determine the magnitude of prolonged turnaround time...
Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case-Control Study [0.03%]
孟加拉国乳腺癌易感性的MDM4基因多态性(rs1380576和rs4245739)相关性病例对照研究
J M Aousiful Islam,Sharif Ahamed,Shafiqul Islam et al.
J M Aousiful Islam et al.
Background: Breast cancer (BC) is the most common malignancy among Bangladeshi women. MDM4 gene polymorphisms have been implicated in BC susceptibility, but data from South Asian populations remain limited. ...
A Hybrid Qualitative-Quantitative FMEA Model for Risk Management in Clinical Laboratory Automation: A Case Study Integrating ISO 15189:2022 [0.03%]
临床实验室自动化风险管理的混合定性定量FMEA模型:结合ISO 15189:2022的案例研究
Mengqi Wei,Mingyang Li,Yu Lin et al.
Mengqi Wei et al.
Background: Total laboratory automation (TLA) system greatly enhances testing efficiency and accuracy, yet potential process-related risks may cause inaccurate results or delayed reports. Based on the ISO 15189:2022 stand...