Lipid Profile Alterations Across Coronary Heart Disease, Metabolic Syndrome, and Nephrotic Syndrome [0.03%]
冠心病、代谢综合征和肾病综合征的血脂谱改变
Shudong Tan,Tianji Qu,Jing Ai et al.
Shudong Tan et al.
Background: Dyslipidemia was a hallmark of metabolic disturbances in coronary heart disease (CHD), metabolic syndrome (MetS), and nephrotic syndrome (NS), yet the specific lipid profile patterns characteristic of each dis...
An Integrated Genotyping Strategy for α/β-Thalassemia: Based on the Analysis of the Coding Sequences and Expression Levels of HBA2, HBA1, and HBB in Peripheral Blood mRNA [0.03%]
基于外周血mRNA的HBA2、HBA1和HBB表达水平及编码序列分析的α/β地贫整合基因分型策略
Hongjian Chen,Qi Yao,Mianai Fu
Hongjian Chen
Objective: To analyze the clinical diagnostic value for thalassemia genotyping using peripheral blood mRNA. Methods: Total RNA was extr...
Integrated ESR and PLT-H Measurement Using the BC-6800 Plus Hematology Analyzer: A Comprehensive Analytical Evaluation [0.03%]
BC-6800Plus血液细胞分析仪集约化ESR和PLT-H检测临床应用价值评估
Meilin Chen,Jinghai Yan,Manman Ye et al.
Meilin Chen et al.
Background: Complete blood count (CBC) and erythrocyte sedimentation rate (ESR) are essential tests in clinical practice. The Mindray BC-6800 Plus integrates CBC and ESR analysis through its Easy-W ESR module and a hybrid...
Validation of the Primerdesign Quantitative Allele Specific Amplification Kit for the Detection of JAK2V617F Mutation [0.03%]
用于检测JAK2V617F突变的Primerdesign定量等位基因特异性扩增检测试剂盒验证
Deborah Vaz,Tshiphiri Netshidzivhani,Johan Potgieter
Deborah Vaz
Introduction: Janus Kinase 2 (JAK2) is a tyrosine kinase involved in cellular signalling. A point mutation in codon 617 of JAK2 (JAK2V617F) causes a gain-of-function effect that stimulates proliferation of myeloid cells. ...
Resolving Bivalirudin Interference on Fibrinogen Testing by the Use of Activated Carbon [0.03%]
活性炭用于解决拜瑞妥对纤维蛋白原检测的干扰
Jia Du,Haiyan Liu,Xiaohui Liu et al.
Jia Du et al.
Background: Direct thrombin inhibitors may lead to falsely low fibrinogen results. The interference of bivalirudin on fibrinogen assays has not been thoroughly evaluated. This study investigates the interference of bivali...
Genotype-Driven Resolution of Panagglutination Over a Decade of Korean Rare Blood Program Case Archives [0.03%]
基于基因型解析稀有血型档案中泛凝集现象的原因——韩国稀有血型库10年存档病例分析
Hyunji Kim,Dong Woo Shin,Sujin Oh et al.
Hyunji Kim et al.
Background: As populations age and chronic disease burden rises, transfusion demand grows in both volume and immunohematologic complexity. When reagent red blood cells (RBCs) in antibody screening and identification panel...
Exploring Uric Acid to HDL Ratio as a Long-Term Biomarker for Diabetes Mellitus [0.03%]
探究尿酸与HDL比值作为长期糖尿病生物标志物
Rana Kolahi,Reza Khademi,Mahboobeh Ghasemzadeh Rahbardar et al.
Rana Kolahi et al.
Background: Diabetes mellitus (DM) poses a major challenge to public health worldwide. The ratio of serum uric acid to high-density lipoprotein cholesterol (UHR) has recently emerged as a promising indicator of inflammati...
Strategies for Monitoring Serum Protein Degradation With an Antibody Array-Based Technology [0.03%]
基于抗体阵列技术监测血清蛋白降解的策略
Yanlin Wang,Min Lang,Wei Huang et al.
Yanlin Wang et al.
Background: Human serum is an ideal body fluid for discovering and monitoring biomarkers for disease diagnosis and treatment response. However, intrinsic proteolytic degradation during sample handling may compromise bioma...
The Genetic Link Between Primary Immune Thrombocytopenia and Depression/Anxiety Disorders: A Two-Sample Mendelian Randomization Study [0.03%]
原发性免疫性血小板减少症和抑郁症/焦虑症的遗传联系：两样本孟德尔随机化研究
Le Jiang,Ya-Jing Zhao,Shou-Qing Han et al.
Le Jiang et al.
Background: Primary immune thrombocytopenia (ITP) is an autoimmune bleeding disorder with complex immunopathogenesis. Its major symptoms, such as bleeding tendency and fatigue, may predispose patients to depression and an...
Synthesis, Antitumor Activity Evaluation and Mechanistic Study of Novel Bis-Heterocyclic Chalcones Against Liver Cancer [0.03%]
新型双杂环查尔康素的合成、抗肿瘤活性评价及机制研究针对肝癌
Zhifen Li,Jingbo Ma,Xiannian Lv et al.
Zhifen Li et al.
Background: Chalcones and heterocyclic compounds exhibit remarkably high activity in medicinal chemistry. In recent years, bis-chalcones have been reported to possess excellent anticancer activity. We synthesized a series...