The Transcriptional Regulator FOXR1 Is Required for Normal Early Embryogenesis but Dispensable for Male Fertility in Mice [0.03%]
转录调节因子FOXR1在正常早期胚胎发育中是必需的，但在小鼠雄性生育中却是可有可无的
Soazik P Jamin,Fabrice G Petit,Christine Kervarrec et al.
Soazik P Jamin et al.
FOXR1 belongs to the large conserved F-box family of DNA binding transcription factors that are involved in various developmental processes and diseases. The gene is important for embryogenesis in a fish model, brain development in mammals,...
Extracellular Vesicles Derived From Antral Follicles Significantly Change the Transcriptional Profile of Cumulus Cells and Oocytes During Pre-In Vitro Maturation in Cattle [0.03%]
牛卵泡外泌体对体外成熟前卵丘细胞和卵母细胞转录组的影响
Gisele Zoccal Mingoti,Giovana Barros Nunes,Mirela Brochado Souza-Cáceres et al.
Gisele Zoccal Mingoti et al.
Cumulus-oocyte complexes (COCs) used for in vitro production (IVP) of bovine embryos originate from antral follicles of different sizes, leading to variations in developmental competence. To address this, pre-in vitro maturation (pre-IVM) a...
Immunostaining of Gonadotropin Receptors in Ovarian Follicles of Bos Indicus Cows With High and Low Antral Follicle Count [0.03%]
高基础卵泡数和低基础卵泡数婆罗门母牛卵巢卵泡促性腺激素受体的免疫组织化学定位研究
Deborah Nakayama Yokomizo,Mariana Moreira Dos Anjos,Ana Karolyne Alves Miguel et al.
Deborah Nakayama Yokomizo et al.
This study aimed to assess differences in the immunostaining intensity of follicle-stimulating hormone receptor (FSHr) and leutenizing hormone receptor (LHr) receptors in the ovarian follicles of Bos indicus cows with high or low antral fol...
Expression of miRNAs Associated With Embryo Development and DNA Damage Response in Porcine Embryos [0.03%]
与胚胎发育和DNA损伤修复相关的microRNA在猪胚胎中的表达分析
Gabriel Pineda,Fernanda Luiza Facioli,Mariana Priotto de Macedo et al.
Gabriel Pineda et al.
Embryo genome activation (EGA) is a crucial event implicated in proper embryonic development. Similarly, the DNA Damage Response (DDR) is essential for correcting or preventing occasional errors during embryonic cell division that could res...
Extended In Vitro Maturation Enhances Oocyte Developmental Competence but Alters Gene Expression in Bovine Embryos Derived From Oocytes With Slow-Predicted Nuclear Maturation Speed [0.03%]
体外成熟延长提升牛卵母细胞发育潜能，但会改变慢速预测的核成熟卵母细胞衍生胚胎中的基因表达
Thomas Chia-Tang Ho,Takashi Tanida,Takashi Fujii et al.
Thomas Chia-Tang Ho et al.
To identify the optimal in vitro maturation (IVM) duration for bovine oocytes with different nuclear maturation speeds (NMS), this study assessed how varying IVM durations (24, 28, and 32 h) affect developmental competence and embryo qualit...
Uterine Extracellular Vesicles Can Emulate the Long-Term Effects of Post-Partum Negative Energy Balance in Dairy Cows [0.03%]
产后负能量平衡对 dairy cows 的长期影响可以通过子宫细胞外囊泡模拟实现
Juliana Germano Ferst,Matheus Andrade Chaves,Amanda Nespolo Silva et al.
Juliana Germano Ferst et al.
Dairy cows often experience a period of negative energy balance (NEB) during the post-calving period, which can significantly impact economic outcomes due to extended calving-to-conception intervals and overall reduced fertility. This reduc...
Spexin Expression in Porcine Corpus Luteum, Its Regulation and Modulatory Effect on Steroidogenesis [0.03%]
猪黄体中Spexin的表达及其对类固醇生成的调节作用和调制效应研究
Patrycja Kurowska,Ewa Mlyczyńska,Kinga Gaździk et al.
Patrycja Kurowska et al.
Spexin (SPX) is adipokine linked with the regulation of metabolism and reproduction. However, its role in the corpus luteum (CL) is unknown. Our aim was to determine the expression of SPX and galanin receptor 2 and 3 (GALR2/3), in the porci...
Impact of Neutral Sphingomyelinase Inhibition on Small Extracellular Vesicle Production by Mural Granulosa Cells and In Vitro Folliculogenesis in Mice [0.03%]
中性鞘氨醇磷脂酶D抑制对小细胞外囊泡的产生及小鼠体外卵泡发育的影响
Kodai Matsushita,Yuta Matsuno,Kazuma Kita et al.
Kodai Matsushita et al.
Small extracellular vesicles (sEVs) function as critical regulators of ovarian follicular development. Although several pathways, including one involving neutral sphingomyelinase (nSMase), contribute to sEV production, the specific pathway ...
Direct Development of Golf Ball Sponges, Genus Craniella (Demospongiae, Tetractinellida) From the Northeast Atlantic Ocean [0.03%]
来自东北大西洋的高尔夫球海绵（Craniella属，四射海绵总科）的直接发育研究
Paco Cárdenas,Sandrine Chenesseau,Jim Drewery et al.
Paco Cárdenas et al.
Among the eight types of development in sponges, the least common and least studied is direct, non-larval development during viviparity. To supplement our knowledge of this rare type of demosponge development, we present here a description ...
Effects of Aging on Mammalian Spermatogenesis From a Cellular Perspective [0.03%]
从细胞角度分析老化对哺乳动物精子发生的影响
Tao Li,Wenchao Xu,Lisha Yin et al.
Tao Li et al.
Aging refers to the irreversible changes in the structure and function of organisms over time. Under the influence of social and economic factors, the apparent effect of aging on female fertility has been widely recognized; however, its eff...